The effects of SB 204070, a highly potent and selective 5‐HT4 receptor antagonist, on guinea‐pig distal colon
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References (34)
Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
1973 • 12,522 citations
SOME QUANTITATIVE USES OF DRUG ANTAGONISTS
1959 • 3,948 citations
Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.
1978 • 2,400 citations
Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine
1986 • 1,255 citations
Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs
1985 • 845 citations
The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site
1984 • 598 citations
A proposed new nomenclature for 5-HT receptors
1993 • 551 citations
A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system.
1988 • 435 citations
Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids
1988 • 296 citations
Characterization of adenosine receptors in rat brain by (?)[3H]N6-phenylisopropyladenosine
1980 • 296 citations
Development of a radioligand binding assay for 5‐HT4 receptors in guinea‐pig and rat brain
1993 • 285 citations
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
1991 • 225 citations
Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron)
1989 • 216 citations
Pharmacological analysis of drug-receptor interaction
1994 • 212 citations
A 5‐hydroxytryptamine receptor in human atrium
1990 • 193 citations
The 5-HT4 receptor: naughty, but nice
1989 • 157 citations
The 5‐HT4 Receptor
1993 • 145 citations
[3H]-BRL 43694 (granisetron), a specific ligand for 5-HT3 binding sites in rat brain cortical membranes
1989 • 138 citations
A 5-HT receptor in the central nervous system, positively coupled with adenylate cyclase, is antagonized by ICS 205 930
1988 • 137 citations
The kinetics of action of acetylcholine antagonists in smooth muscle
1966 • 122 citations
Identification of putative 5-HT4 receptors in guinea-pig ascending colon
1991 • 119 citations
The pharmacological characterization of 5‐HT3 receptors in three isolated preparations derived from guinea‐pig tissues
1990 • 110 citations
5-HT1D receptors in guinea-pig and pigeon brain
1989 • 79 citations
SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea pig ileum
1992 • 78 citations
Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080
1993 • 74 citations
The guinea‐pig distal colon ‐ a sensitive preparation for the investigation of 5‐HT4 receptor‐mediated contractions
1993 • 74 citations
Azabicycloalkyl benzimidazolones: Interaction with serotonergic 5-HT3 and 5-HT4 receptors and potential therapeutic implications
1991 • 66 citations
The classification of 5‐hydroxytryptamine receptors
1988 • 52 citations
Evidence for inhibition by ICS 205-930 and stimulation by BRL 34915 of K+ conductance in cardiac muscle
1987 • 50 citations
Endothelium‐dependent and ‐independent effects of exogenous ATP, adenosine, GTP and guanosine on vascular tone and cyclic nucleotide accumulation of rat mesenteric artery
1992 • 39 citations
(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide
1993 • 38 citations
Unsurmountable antagonism to 5-hydroxytryptamine in rat kidney results from pseudoirreversible inhibition rather than multiple receptors or allosteric receptor modulation.
1989 • 35 citations
Current problems and future requirements for 5-hydroxytryptamine receptor classification.
1990 • 7 citations
Current problems and future requirements for 5-hydroxytryptamine receptor classification.
1990 • 3 citations