The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ m coupling efficiency to adenylate cyclase and in agonist‐induced receptor desensitization

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

1992 • 766 citations

Regulatory Peptides of the Hypothalamus

1977 • 395 citations

Adrenergic Receptors as Models for G Protein-Coupled Receptors

1992 • 340 citations

Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase.

1992 • 313 citations

Molecular cloning and functional expression of a brain-specific somatostatin receptor.

1992 • 299 citations

Cloning and expression of a novel mouse somatostatin receptor (SSTR2B)

1992 • 270 citations

Cloning and characterization of a fourth human somatostatin receptor.

1993 • 218 citations

Somatostatin hyperpolarizes hippocampal pyramidal cells in vitro

1981 • 209 citations

Expression cloning of a rat brain somatostatin receptor cDNA.

1992 • 201 citations

Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates Function

1992 • 192 citations

Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.

1985 • 190 citations

Multiple Gene Transcripts of the Somatostatin Receptor SSTR2: Tissue-Selective Distribution and cAMP Regulation

1993 • 165 citations

Molecular cloning of a somatostatin-28 receptor and comparison of its expression pattern with that of a somatostatin-14 receptor in rat brain.

1992 • 160 citations

Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2

1993 • 156 citations

Somatostatin-14 and somatostatin-28 induce opposite effects on potassium currents in rat neocortical neurons.

1989 • 145 citations

Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells.

1987 • 103 citations

Cloning and expression of a rat somatostatin receptor enriched in brain.

1992 • 101 citations

Somatostatin Mediation of Adenohypophysial Secretion

1986 • 101 citations

Somatostatin-14 and somatostatin-28 inhibit calcium currents in rat neocortical neurons

1990 • 77 citations

Multiple Gi protein subtypes regulate a single effector mechanism.

1991 • 67 citations

Actions of growth hormone-releasing factor and somatostatin on adenylate cyclase and growth hormone release in rat anterior pituitary

1984 • 45 citations

The Rat SSTR2 Somatostatin Receptor Subtype Is Coupled to Inhibition of Cyclic AMP Accumulation

1993 • 40 citations

Analogues of Somatostatin Bind Selectively to Brain Somatostatin Receptor Subtypes

1992 • 35 citations

Characteristics of somatostatin desensitization in the pituitary tumor cell line AtT-20.

1988 • 30 citations

The effect of baclofen and somatostatin on neuronal activity in the rat ventromedial hypothalamic nucleus in vitro

1992 • 17 citations

Excitatory amino acid receptors: NMDA modulatory sites, kainate cloned and a new role in AIDS

1990 • 14 citations