UV activation of mammalian stress protiens

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

Oxidative Stress: Oxidants and Antioxidants.

1992 • 1,193 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells.

1984 • 874 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

The ornithine decarboxylase gene is a transcriptional target of c-Myc.

1993 • 759 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

1992 • 647 citations

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal

1993 • 646 citations

Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells.

1991 • 635 citations

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

1995 • 603 citations

Activation of ternary complex factor Elk-1 by MAP kinases.

1993 • 561 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts.

1994 • 520 citations

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases.

1994 • 463 citations

Involvement of growth factor receptors in the mammalian UVC response

1994 • 456 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin

1993 • 394 citations

UVA irradiation induces collagenase in human dermal fibroblasts in vitro and in vivo

1991 • 392 citations

New trends in photobiology

1992 • 388 citations

Activation of NF-kappa B in vivo is regulated by multiple phosphorylations.

1994 • 362 citations

Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element.

1988 • 271 citations

UVA‐INDUCED AUTOCRINE STIMULATION OF FIBROBLAST‐DERIVED COLLAGENASE/MMP‐1 BY INTERRELATED LOOPS OFINTERLEUKIN–1 andINTERLEUKIN–6

1994 • 271 citations

UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

1993 • 262 citations

An emerging family of dual specificity MAP kinase phosphatases

1995 • 256 citations

Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer

1995 • 219 citations

Ultraviolet A Irradiation Stimulates Collagenase Production in Cultured Human Fibroblasts

1992 • 213 citations

Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene

1992 • 212 citations

Singlet oxygen: a primary effector in the ultraviolet A/near-visible light induction of the human heme oxygenase gene.

1993 • 204 citations

Interleukin-10 Production by Cultured Human Keratinocytes: Regulation by Ultraviolet B and Ultraviolet A1 Radiation

1995 • 196 citations

ACTION SPECTRA FOR THE INDUCTION OF PYRIMIDINE(6‐4)PYRIMIDONE PHOTOPRODUCTS AND CYCLOBUTANE PYRIMIDINE DIMERS IN NORMAL HUMAN SKIN FIBROBLASTS

1987 • 195 citations

Wavelength specific patterns of p53 induction in human skin following exposure to UV radiation.

1993 • 195 citations

UVA irradiation stimulates the synthesis of various matrix‐metalloproteinases (MMPs) in cultured human fibroblasts

1993 • 170 citations

Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes.

1988 • 169 citations

ACTIVATION OF NF‐KB IN HUMAN SKIN FIBROBLASTS BY THE OXIDATIVE STRESS GENERATED BY UVA RADIATION

1995 • 155 citations

New trends in photobiology

1993 • 152 citations

Singlet oxygen induces collagenase expression in human skin fibroblasts

1993 • 151 citations

Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation.

1994 • 145 citations

Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase

1995 • 139 citations

THE ROLE OF EPIDERMAL CYTOKINES IN THE GENERATION OF CUTANEOUS IMMUNE REACTIONS and ULTRAVIOLET RADIATION‐INDUCED IMMUNE SUPPRESSION

1995 • 137 citations

UVA-Induced Autocrine Stimulation of Fibroblast-Derived-Collagenase by IL-6: A Possible Mechanism in Dermal Photodamage?

1993 • 136 citations

Regulation of human ornithine decarboxylase expression by the c-Myc.Max protein complex.

1993 • 126 citations

UV irradiation-induced interleukin-1 and basic fibroblast growth factor synthesis and release mediate part of the UV response.

1993 • 126 citations

TWO GENES CONTRIBUTE TO DIFFERENT EXTENTS TO THE HEME OXYGENASE ENZYME ACTIVITY MEASURED IN CULTURED HUMAN SKIN FIBROBLASTS AND KERATINOCYTES: IMPLICATIONS FOR PROTECTION AGAINST OXIDANT STRESS

1995 • 115 citations

Analysis of the Mechanism of Ultraviolet (UV) B Radiation – Induced Prostaglandin E2 Synthesis by Human Epidermoid Carcinoma Cells

1993 • 107 citations

Induction of plasminogen activator by UV light in normal and xeroderma pigmentosum fibroblasts.

1981 • 96 citations

The mammalian UV response: Mechanism of DNA damage induced gene expression

1994 • 94 citations

Ultraviolet Light Induces Epidermal ornithine Decarboxylase Activity

1978 • 90 citations

Reactive oxygen species are involved in the activation of cellular phospholipase A₂

1992 • 89 citations

Novel protein in human epidermal keratinocytes: regulation of expression during differentiation.

1988 • 83 citations

Induction of apoptosis by tumor suppressor genes and oncogenes

1995 • 81 citations

ACTIVATION OF HUMAN IMMUNODEFICIENCY VIRUS BY ULTRAVIOLET RADIATION

1990 • 75 citations

c-Fos is involved in the cellular defence against the genotoxic effect of UV radiation

1995 • 74 citations

Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells.

1988 • 73 citations

Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes

1990 • 72 citations

Induction of urokinase-type plasminogen activator by UV light in human fetal fibroblasts is mediated through a UV-induced secreted protein.

1987 • 69 citations

Effect of Aging and Habitual Sun Exposure on the Genetic Response of Cultured Human Keratinocytes to Solar-Simulated Irradiation

1992 • 67 citations

Differential regulation of c-fos, fosB, c-jun, junB, bcl-2 and bax expression in rat skin following single or chronic ultraviolet irradiation and in vivo modulation by antisense oligodeoxynucleotide superfusion.

1994 • 63 citations

Long-Wave Ultraviolet Light Induces Phospholipase Activation in Cultured Human Epidermal Keratinocytes

1990 • 63 citations

Immediate and delayed molecular response of human keratinocytes to solar-simulated irradiation.

1991 • 62 citations

Interaction of upstream stimulatory factor with the human heme oxygenase gene promoter

1990 • 62 citations

PROTECTIVE ROLE OF BUTYLATED HYDROXYTOLUENE AND CERTAIN CAROTENOIDS IN PHOTOCARCINOGENESIS*

1991 • 56 citations

STUDY OF THE EFFECTS OF ULTRAVIOLET LIGHT ON BIOMEMBRANES—IV. THE EFFECT OF OXYGEN ON UV‐INDUCED HEMOLYSIS AND LIPID PHOTOPEROXIDATION IN RAT ERYTHROCYTES AND LIPOSOMES

1975 • 52 citations

ULTRAVIOLET RADIATION STIMULATES THE RELEASE OF ARACHIDONIC ACID FROM MAMMALIAN CELLS IN CULTURE*

1985 • 52 citations

Ultraviolet A (320–380 nm) radiation causes an alteration in the binding of a specific protein/protein complex to a short region of the promoter of the human heme oxygenase 1 gene

1993 • 50 citations

Evidence that DNA Damage Is a Mediate in Ultraviolet B Radiation-Induced Inhibition of Human Gene Expression: Ultraviolet B Radiation Effects on Intercellular Adhesion Molecule-1 (ICAM-1) Expression

1994 • 45 citations

Ultraviolet radiation induction of ornithine decarboxylase in rat keratinocytes.

1990 • 45 citations

UVB-induced DNA breaks interfere with transcriptional induction of c-fos.

1993 • 42 citations

Distinct structural specificities for functional coupling of the epidermal growth factor receptor to calcium-signalling versus phospholipase A2 responses

1991 • 34 citations

UVB radiation induces phosphorylation of the epidermal growth factor receptor, decreases EGF binding and blocks EGF induction of ornithine decarboxylase gene expression in SV40‐transformed human keratinocytes

1993 • 32 citations

Acute and chronic ultraviolet radiation induction of epidermal ornithine decarboxylase activity in hairless mice.

1990 • 30 citations

Ultraviolet Irradiation Induces c-fos but Not c-Ha-ras Proto-Oncogene Expression in Human Epidermis

1994 • 27 citations

Involvement of fos in spontaneous and ultraviolet light‐induced genetic changes

1991 • 23 citations

Modulation of the expression of intercellular adhesion molecule-1 (ICAM-1) in human keratinocytes by ultraviolet (UV) radiation

1992 • 15 citations

Specific mRNAs accumulate in long-wavelength UV-irradiated mouse epidermis

1990 • 11 citations

U.v. wavelength dependence for the induction of ornithine decarboxylase activity in hairless mouse epidermis

1986 • 11 citations

Ultraviolet B radiation induction of ornithine decarboxylase gene expression in mouse epidermis

1990 • 9 citations

The acute effects of ultraviolet-B radiation on c-myc and c-Ha ras expression in normal human epidermis

1993 • 8 citations

Effects of Butylated Hydroxyanisole on Ornithine Decarboxylase Activity Induced by Ultraviolet-B and PUVA in Mouse Skin

1992 • 4 citations