Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

1992 • 1,089 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

Transcriptional regulation

1991 • 893 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Reporter genes: Application to the study of mammalian gene transcription

1990 • 466 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

Transcriptional control of rat heme oxygenase by heat shock.

1987 • 415 citations

Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene.

1994 • 401 citations

Regulation of the transcription factors NF-κB and AP-1 by redox changes

1994 • 310 citations

Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro

1988 • 300 citations

Heme Oxygenase: Clinical Applications and Functions

1992 • 264 citations

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.

1994 • 207 citations

Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene.

1992 • 194 citations

Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5' sequences are required for induction by heme or heavy metals.

1994 • 153 citations

Identification of a cis-acting element that is responsible for cadmium-mediated induction of the human heme oxygenase gene.

1994 • 130 citations

Multiple elements within the 5' distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals.

1994 • 130 citations

Heme oxygenase induction by CoCl2, Co-protoporphyrin IX, phenylhydrazine, and diamide: Evidence for oxidative stress involvement

1991 • 87 citations

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.

1994 • 82 citations

Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells

1992 • 80 citations

Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro.

1992 • 80 citations

Identification of a cis-regulatory element and putative trans-acting factors responsible for 12-O-tetradecanoylphorbol-13-acetate (TPA)-mediated induction of heme oxygenase expression in myelomonocytic cell lines.

1993 • 57 citations

Ultraviolet A (320–380 nm) radiation causes an alteration in the binding of a specific protein/protein complex to a short region of the promoter of the human heme oxygenase 1 gene

1993 • 50 citations

Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter

1989 • 42 citations