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Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

Data up to Jan 2025

Published1997
Citations269
References56

Total Citations Per Year

Abstract

References (56)

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

The Pathogenesis of Insulin-Dependent Diabetes Mellitus

1994 • 1,077 citations

Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system

1991 • 1,071 citations

Epithelial Mucin Genes

1995 • 982 citations

Strategies for epitope analysis using peptide synthesis

1987 • 887 citations

Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer.

1989 • 510 citations

Cell membrane-associated mucins and their adhesion-modulating property

1992 • 472 citations

Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer.

1994 • 467 citations

Th1 And Th2 Cells: Different Patterns Of Lymphokine Secretion Lead To Different Functional Properties

1989 • 460 citations

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells.

1989 • 453 citations

Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells.

1991 • 353 citations

Tolerance, Danger and the Extended Family

1994 • 337 citations

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen.

1988 • 310 citations

Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients.

1994 • 307 citations

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium.

1987 • 288 citations

A Phase I Trial of a Synthetic Mucin Peptide Vaccine

1996 • 268 citations

In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild‐type p53

1993 • 267 citations

A Phase I Evaluation of the Safety and Immunogenicity of Vaccination with Recombinant gp160 in Patients with Early Human Immunodeficiency Virus Infection

1991 • 248 citations

Human epithelial tumor antigen cDNA sequences

1990 • 242 citations

A short sequence, within the amino acid tandem repeat of a cancer‐associated mucin, contains immunodominant epitopes

1989 • 236 citations

Cytotoxic T cells from ovarian malignant tumors can recognize polymorphic epithelial mucin core peptides.

1993 • 213 citations

Oxidative/reductive conjugation of mannan to antigen selects for T1 or T2 immune responses.

1995 • 192 citations

Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A).

1995 • 188 citations

Antibodies Against Mucin-Associated Sialyl-Tn Epitopes Correlate with Survival of Metastatic Adenocarcinoma Patients Undergoing Active Specific Immunotherapy with Synthetic STn Vaccine

1996 • 184 citations

Immunization of breast cancer patients using a synthetic sialyl-Tn glycoconjugate plus Detox adjuvant

1993 • 183 citations

Expression of MUC1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient.

1994 • 180 citations

Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.

1996 • 180 citations

Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA.

1993 • 180 citations

Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method

1975 • 141 citations

Cell-mediated immune responses to MUC1 fusion protein coupled to mannan

1996 • 138 citations

Humoral immune response to polymorphic epithelial mucin (MUC-1) in patients with benign and malignant breast tumours

1996 • 135 citations

Cellular Mucins: Targets for Immunotherapy

2017 • 130 citations

Active Immunization of Human Ovarian Cancer Patients Against a Common Carcinoma (Thomsen-Friedenreich) Determinant Using a Synthetic Carbohydrate Antigen

1992 • 121 citations

Monoclonal antibodies reactive with mucin expressed in breast cancer

1989 • 114 citations

Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients

1995 • 113 citations

Human B-cell immune response to the polymorphic epithelial mucin.

1993 • 109 citations

Cellular Mucins: Targets for Immunotherapy

1994 • 102 citations

Epithelial Mucin Genes

1995 • 84 citations

Immune Responses of Mice and Human Breast Cancer Patients following Immunization with Synthetic Sialyl‐Tn Conjugated to KLH Plus Detox Adjuvant

1993 • 83 citations

Immunization of colorectal cancer patients with modified ovine submaxillary gland mucin and adjuvants induces IgM and IgG antibodies to sialylated Tn.

1992 • 79 citations

Murine immune response to cells transfected with human MUC1: immunization with cellular and synthetic antigens.

1994 • 79 citations

Lowering the tone: mechanisms of immunodominance among epitopes with low affinity for MHC

1996 • 74 citations

HLA A2601-restricted CTLs recognize a peptide antigen expressed on squamous cell carcinoma.

1995 • 72 citations

T Cell Anergy

1993 • 66 citations

CTL in mice immunized with human mucin 1 are MHC-restricted.

1995 • 65 citations

Natural human anti-Gal alpha(1,3)Gal antibodies react with human mucin peptides.

1997 • 59 citations

Breast cancer immunotherapy: Current status and future prospects

1996 • 48 citations

Epitope mapping of anti-breast and anti-ovarian mucin monoclonal antibodies

1992 • 41 citations

Production of anti-breast cancer monoclonal antibodies using a glutathione-S-transferase-MUC1 bacterial fusion protein

1993 • 41 citations

Recognition of an octapeptide sequence by multiple Galα(1,3)Gal‐binding proteins

1996 • 35 citations

Molecular aspects of mucins

1988 • 33 citations

Human tumor-specific cytotoxic T cell lines generated from tumor-draining lymph node infiltrate.

1988 • 23 citations

Human antibodies against the polymorphic epithelial mucin in ovarian cancer patients recognise a novel sequence in the tandem repeat region

1996 • 22 citations

Enhanced expression of HLA-A,B,C and inducibility of TAP-1, TAP-2, and HLA-A,B,C by interferon-gamma in a multidrug-resistant small cell lung cancer line.

1994 • 16 citations

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Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1… (1997) – Journal of Clinical Investigation | Metascience Observatory Explorer