Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase D.

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Phosphatidylinositol 3-Kinase Encoded by Yeast VPS 34 Gene Essential for Protein Sorting

1993 • 909 citations

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

1993 • 900 citations

Regulation of inositol phospholipid-specific phospholipase C isozymes.

1992 • 740 citations

Phospholipase D: a Downstream Effector of ARF in Granulocytes

1994 • 636 citations

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate

1993 • 449 citations

Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid

1994 • 410 citations

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

1992 • 368 citations

Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca2+-activated secretion

1993 • 346 citations

Purification of polyphosphoinositides by chromatography on immobilized neomycin.

1978 • 323 citations

Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.

1993 • 278 citations

Binding of neomycin to phosphatidylinositol 4,5-biphosphate (PIP2)

1989 • 261 citations

Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol

1993 • 218 citations

Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.

1987 • 197 citations

GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipids.

1994 • 192 citations

ARF signaling: A potential role for phospholipase D in membrane traffic

1993 • 161 citations

Phospholipase D and cell signaling

1993 • 161 citations

Phospholipid transfer proteins: a biological debut

1991 • 159 citations

Signal-activated phospholipases

1994 • 134 citations

Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product.

1993 • 113 citations

ATP stimulates the hydrolysis of phosphatidylethanolamine in NIH 3T3 cells. Potentiating effects of guanosine triphosphates and sphingosine.

1990 • 110 citations

Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells

1992 • 104 citations

Phosphatidylinositol kinase. A component of the chromaffin-granule membrane

1973 • 91 citations

Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles

1991 • 83 citations

Phospholipase D activity in phagocytic leucocytes is synergistically regulated by G-protein- and tyrosine kinase-based mechanisms

1993 • 78 citations

Requirement for phosphatidylinositol 4,5-bisphosphate in the Ca(2+)-induced phospholipid redistribution in the human erythrocyte membrane.

1994 • 75 citations

Characterization of aminoglycoside-lipid interactions and development of a refined model for ototoxicity testing

1984 • 64 citations

Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes

1991 • 62 citations

Inhibition of neural phospholipase D activity by aminoglycoside antibiotics

1991 • 52 citations

ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes.

1993 • 50 citations

Ca2+ inhibits guanine nucleotide-activated phospholipase D in neural-derived NG108-15 cells.

1991 • 43 citations

Coated vesicles contain a phosphatidylinositol kinase.

1985 • 39 citations

Phosphatidylinositol kinase of bovine adrenal chromaffin granules: Kinetic properties and inhibition by low concentrations of Ca2+

1988 • 34 citations

Protein-mediated intermembrane contact specifically enhances Ca2+-induced fusion of phosphatidate-containing membranes

1983 • 32 citations

A synthetic peptide of the N‐terminus of ADP‐ribosylation factor (ARF) inhibits regulated exocytosis in adrenal chromaffin cells

1993 • 25 citations

Phosphoinositides in vesicular traffic

1994 • 24 citations

Binding of neomycin and calcium to phospholipids and other anionic compounds.

1986 • 22 citations

Lipid Metabolism in Signaling Systems

1993 • 18 citations

Requirement of adenosine 5′-triphosphate and Ca2+ for guanosine 5′-triphosphate-binding protein-mediated phospholipase D activation in rat pheochromocytoma PC12 cells

1993 • 10 citations