Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

NUCLEOSIDE PHOSPHOROTHIOATES

1985 • 830 citations

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

1987 • 472 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Phosphatidylethanol Formation via Transphosphatidylation by Rat Brain Synaptosomal Phospholipase D

1987 • 342 citations

Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes.

1988 • 307 citations

Gaining access to the cytosol: the technique and some applications of electropermeabilization

1986 • 275 citations

Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.

1987 • 253 citations

Regulation of Phospholipase D in HL-60 Granulocytes

1989 • 250 citations

Choline-linked Phosphoglycerides

1989 • 234 citations

Activation of human neutrophil phospholipase D by three separable mechanisms

1990 • 220 citations

Cyclic Nucleotide-induced Maturation of Human Promyelocytic Leukemia Cells

1982 • 213 citations

Coomassie brilliant blue staining of lipids on thin-layer plates

1984 • 211 citations

Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil

1989 • 204 citations

Thyrotropin-releasing hormone activates a Ca2+-dependent polyphosphoinositide phosphodiesterase in permeable GH3 cells. GTP gamma S potentiation by a cholera and pertussis toxin-insensitive mechanism.

1986 • 197 citations

Phospholipase D

1978 • 190 citations

P2-Purinergic Agonists Stimulate Phosphodiesteratic Cleavage of Phosphatidylcholine in Endothelial Cells

1989 • 180 citations

Receptor regulation of choline phospholipid hydrolysis

1989 • 167 citations

Ca2+-dependent conversion of phosphatidylinositol to phosphatidate in neutrophils stimulated with fMet-Leu-Phe or ionophore A23187

1984 • 152 citations

Phosphatidylethanol Biosynthesis in Ethanol-exposed NG108-15 Neuroblastoma X Glioma Hybrid Cells

1989 • 151 citations

Phorbol Ester Stimulates the Hydrolysis of Phosphatidylethanolamine in Leukemic HL-60, NIH 3T3, and Baby Hamster Kidney Cells

1989 • 140 citations

Activation of phospholipase D by sphingoid bases in NG108-15 neural-derived cells.

1990 • 134 citations

Ca^{2 +}‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation

1987 • 130 citations

The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils

1989 • 123 citations

Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O

1988 • 121 citations

Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells.

1989 • 118 citations

ATP stimulates the hydrolysis of phosphatidylethanolamine in NIH 3T3 cells. Potentiating effects of guanosine triphosphates and sphingosine.

1990 • 110 citations

Phosphoinositide hydrolysis by guanosine 5′-[γ-thio]triphosphate-activated phospholipase C of turkey erythrocyte membranes

1988 • 106 citations

ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin‐sensitive guanine nucleotide‐binding protein coupled to phospholipase C

1989 • 102 citations

Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides.

1990 • 101 citations

Guanine nucleotides induce tyrosine phosphorylation and activation of the respiratory burst in neutrophils

1989 • 101 citations

A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization.

1990 • 100 citations

Muscarinic acetylcholine receptor regulates phosphatidylcholine phospholipase D in canine brain

1989 • 96 citations

Phospholipase D in homogenates from HL-60 granulocytes: Implications of calcium and G protein control

1989 • 91 citations

Phorbol ester treatment of intact rabbit platelets greatly enhances both the basal and guanosine 5′-[γ-thio]triphosphate-stimulated phospholipase D activities of isolated platelet membranes. Physiological activation of phospholipase D may be secondary to activation of phospholipase C

1990 • 90 citations

Phosphatidylethanol formation in human platelets: Evidence for thrombin-induced activation of phospholipase D

1988 • 88 citations

The fatty acid composition of phosphatidylinositol, phosphatidate and 1,2-diacylglycerol in stimulated human neutrophils

1984 • 80 citations

12-O-tetradecanoylphorbol-13-acetate activates phosphatidylethanol and phosphatidylglycerol synthesis by phospholipase D in cell lysates

1988 • 78 citations

Evidence for a protein kinase C‐directed mechanism in the phorbol diester‐induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine

1989 • 74 citations

Activation of Phospholipase D by the Fucose-Sulfate Glycoconjugate That Induces An Acrosome Reaction in Spermatozoa

1989 • 74 citations

On the mechanism of muscarinic hydrolysis of choline phospholipids in the heart

1988 • 59 citations

Biochemical characterization of phospholipase D activity from human neutrophils

1989 • 55 citations

Pertussis toxin produces differential inhibitory effects on basal, P2-purinergic, and chemotactic peptide-stimulated inositol phospholipid breakdown in HL-60 cells and HL-60 cell membranes.

1990 • 45 citations

ATP and guanine nucleotide dependence of neutrophil activation. Evidence for the involvement of two distinct GTP-binding proteins.

1990 • 43 citations

P2-Purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells

1990 • 43 citations

Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways

1990 • 37 citations

Long-term phorbol ester treatment dissociates phospholipase D activation from phosphoinositide hydrolysis and prostacyclin synthesis in endothelial cells stimulated with bradykinin

1989 • 35 citations

Chemotactic peptide, calcium and guanine nucleotide regulation of phospholipase C activity in membranes from DMSO-differentiated HL60 cells

1987 • 33 citations

Ca2+-induced secretion by electropermeabilized human neutrophils. The roles of Ca2+, nucleotides and protein kinase C

1990 • 30 citations

Activation of electropermeabilized neutrophils by adenosine 5′-[γ-thio]triphosphate (ATP[S]). Role of phosphatases in stimulus-response coupling

1989 • 27 citations

Hormone-regulated phosphoinositide turnover in permeabilized cells and membranes

1987 • 12 citations