Indirect immunofluorescence localization of β-adrenergic receptors and G-proteins in human A431 cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Immunogenic structure of the influenza virus hemagglutinin

1982 • 759 citations

Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

1985 • 732 citations

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

1987 • 687 citations

Beta-adrenergic receptors: biochemical mechanisms of physiological regulation

1984 • 672 citations

New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates

1979 • 463 citations

CGP-12177. A hydrophilic beta-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells.

1983 • 289 citations

Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.

1988 • 268 citations

G protein multiplicity in eukaryotic signal transduction systems

1988 • 267 citations

From Epinephrine to Cyclic AMP

1988 • 255 citations

The avian beta-adrenergic receptor: primary structure and membrane topology.

1986 • 252 citations

The opsin family of proteins

1986 • 245 citations

Mammalian .beta.2-adrenergic receptor: purification and characterization

1984 • 207 citations

Quantitative electrophoretic transfer of polypeptides from SDS polyacrylamide gels to nitrocellulose sheets: A method for their re-use in immunoautoradiographic detection of antigens

1982 • 190 citations

Relationships within the family of GTP-binding proteins isolated from bovine central nervous system.

1985 • 160 citations

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

1986 • 159 citations

Primary structure of the β‐subunit of bovine transducin deduced from the cDNA sequence

1985 • 155 citations

[1] Production of antibodies by inoculation into lymph nodes

1983 • 148 citations

The carboxyl terminus of the hamster β-adrenergic receptor expressed in mouse L cells is not required for receptor sequestration

1987 • 142 citations

Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells.

1986 • 133 citations

The regulatory subunit of adenylate cyclase interacts with cytoskeletal components

1981 • 129 citations

Recycling of transferrin receptors in A431 cells is inhibited during mitosis.

1984 • 128 citations

Biosynthesis and interconversion of Drosophila nuclear lamin isoforms during normal growth and in response to heat shock.

1987 • 103 citations

Permissive hormone regulation of hormone-sensitive effector systems

1988 • 101 citations

Regulation of G-proteins in differentiation. Altered ratio of alpha- to beta-subunits in 3T3-L1 cells.

1987 • 97 citations

Molecular mechanisms of olfaction.

1988 • 84 citations

Steady-state levels of G-proteins and beta-adrenergic receptors in rat fat cells. Permissive effects of thyroid hormones.

1988 • 83 citations

Purification of a beta 35 form of the beta gamma complex common to G-proteins from human placental membranes.

1987 • 81 citations

(-)-[125I]-iodopindolol, a new highly selective radioiodinated beta-adrenergic receptor antagonist: measurement of beta-receptors on intact rat astrocytoma cells.

1980 • 76 citations

Fat cell .beta.1-adrenergic receptor: structural evidence for existence of disulfide bridges essential for ligand binding

1985 • 74 citations

Fractionation of the beta subunit common to guanine nucleotide-binding regulatory proteins with the cytoskeleton.

1986 • 64 citations

G-proteins of fat-cells Role in hormonal regulation of intracellular inositol 1,4,5-trisphosphate

1986 • 62 citations

Colchicine potentiates β-adrenoreceptor-stimulated cyclic AMP in lymphoma cells by an action distal to the receptor

1978 • 60 citations

The fat cell beta-adrenergic receptor. Purification and characterization of a mammalian beta 1-adrenergic receptor.

1984 • 59 citations

Mammalian beta 1- and beta 2-adrenergic receptors. Immunological and structural comparisons.

1986 • 56 citations

Receptor density and cAMP accumulation: Analysis in CHO cells exhibiting stable expression of a cDNA that encodes the beta2-adrenergic receptor

1988 • 55 citations

The human carcinoma cell line A431 possesses large numbers of functional β‐adrenergic receptors

1984 • 54 citations

beta-Adrenergic agonist activity of a monoclonal anti-idiotypic antibody.

1985 • 53 citations

Heart contains two substrates (Mr = 40,000 and 41,000) for pertussis toxin-catalyzed ADP-ribosylation that co-purify with Ns

1985 • 50 citations

Molecular mechanisms of olfaction

1989 • 47 citations

Localization of β-adrenergic receptors in A431 cells in situ. Effect of chronic exposure to agonist

1989 • 47 citations

Cytoskeletal constraint of the beta-adrenergic receptor in frog erythrocyte membranes.

1980 • 42 citations

Molecular complexes involved in the regulation of adenylate cyclase.

1981 • 39 citations

Purified rat hepatic beta 2-adrenergic receptor. Structural similarities to the rat fat cell beta 1-adrenergic receptor.

1985 • 37 citations

Localization of beta-adrenergic receptors on differentiated cells of the central nervous system in culture.

1987 • 33 citations

Monoclonal antibodies directed against the human A431 β‐adrenergic receptor recognize two major polypeptide chains

1987 • 29 citations

Beta-adrenergic receptors display intramolecular disulfide bridges in situ: analysis by immunoblotting and functional reconstitution.

1988 • 28 citations

Antipeptide antibodies directed against cytoplasmic rhodopsin sequences recognize the beta-adrenergic receptor.

1987 • 26 citations

Altered intracellular adrenoceptor distribution in myocardium of spontaneously hypertensive rats

1987 • 24 citations

Tissue expression and phylogenetic appearance of the β and γ subunits of GTP binding proteins

1985 • 23 citations

Human β-adrenergic receptors. Simultaneous purification of β1- and β2-adrenergic-receptor peptides

1987 • 23 citations

Large-Scale Purification of Beta-Adrenergic Receptors from Mammalian Cells in Culture

1985 • 14 citations

Characterization of the β2-adrenoceptor-dependent adenylate cyclase of A431 epidermoid carcinoma cells

1987 • 12 citations

Changes in immunohistochemical properties of beta-adrenergic receptors in frog erythrocytes by isoproterenol-induced desensitization

1988 • 3 citations