The avian beta-adrenergic receptor: primary structure and membrane topology.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

1984 • 507 citations

Isolation and structure of a rhodopsin gene from D. melanogaster

1985 • 481 citations

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

1986 • 471 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

The yeast α-factor receptor: structural properties deduced from the sequence of theSTE2gene

1985 • 318 citations

Catecholamine-stimulated GTPase cycle. Multiple sites of regulation by beta-adrenergic receptor and Mg2+ studied in reconstituted receptor-Gs vesicles.

1986 • 225 citations

Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase

1985 • 209 citations

Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.

1984 • 158 citations

Use of o-phthalaldehyde to reduce background during automated Edman degradation

1984 • 138 citations

Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase

1984 • 136 citations

A novel catecholamine-activated adenosine cyclic 3',5'-phosphate independent pathway for .beta.-adrenergic receptor phosphorylation in wild-type and mutant S49 lymphoma cells: mechanism of homologous desensitization of adenylate cyclase

1986 • 125 citations

Rhodopsin's protein and carbohydrate structure: Selected aspects

1984 • 124 citations

Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.

1984 • 115 citations

Synthesis of oligonucleotides on cellulose by a phosphotriester method

1980 • 113 citations

Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists.

1985 • 88 citations

Fat cell .beta.1-adrenergic receptor: structural evidence for existence of disulfide bridges essential for ligand binding

1985 • 74 citations

A comparison of the beta-adrenergic receptor of the turkey erythrocyte with mammalian beta1 and beta2 receptors.

1980 • 57 citations

Design and operation of a completely automated Beckman microsequencer

1984 • 47 citations