Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1994 • 983 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells

1969 • 821 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

The neurotrophic factor concept: a reexamination

1993 • 745 citations

Ligands for EPH-Related Receptor Tyrosine Kinases that Require Membrane Attachment or Clustering for Activity

1994 • 720 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3

1991 • 530 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1994 • 332 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

B61 is a ligand for the ECK receptor protein-tyrosine kinase

1994 • 239 citations

Nerve growth factor: a tale of two receptors.

1993 • 215 citations

trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities.

1993 • 178 citations

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis.

1994 • 174 citations

The bride of sevenless and sevenless interaction: Internalization of a transmembrane ligand

1992 • 172 citations

A Novel Immediate-Early Response Gene of Endothelium Is Induced by Cytokines and Encodes a Secreted Protein

1990 • 159 citations

A specific combination of substrates is involved in signal transduction by the kit-encoded receptor.

1991 • 155 citations

HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor.

1989 • 144 citations

EGF Receptor anderbB-2 Tyrosine Kinase Domains Confer Cell Specificity for Mitogenic Signaling

1990 • 142 citations

Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.

1994 • 141 citations

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain

1994 • 135 citations

Molecular and Biochemical Characterization of the Human trk Proto-Oncogene

1989 • 124 citations

Five novel avian Eph-related tyrosine kinases are differentially expressed.

1993 • 112 citations

eph, the largest known family of putative growth factor receptors

1994 • 112 citations

A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein.

1990 • 109 citations

Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors.

1989 • 90 citations

Overexpression confers an oncogenic potential upon the eph gene.

1990 • 88 citations

A chimeric EGF-R-neu proto-oncogene allows EGF to regulate neu tyrosine kinase and cell transformation.

1989 • 87 citations

Characterization of elk, a brain-specific receptor tyrosine kinase.

1991 • 84 citations

Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family.

1991 • 76 citations

A subdomain in the transmembrane domain is necessary for p185neu* activation.

1992 • 73 citations

Identification of a new eph-related receptor tyrosine kinase gene from mouse and chicken that is developmentally regulated and encodes at least two forms of the receptor.

1991 • 66 citations

cDNA cloning and characterization of a ligand for the Cek5 receptor protein-tyrosine kinase.

1994 • 62 citations

Cek5, a membrane receptor-type tyrosine kinase, is in neurons of the embryonic and postnatal avian brain

1992 • 57 citations

Biological and biochemical activities of a chimeric epidermal growth factor-Elk receptor tyrosine kinase.

1993 • 55 citations

Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells.

1987 • 46 citations

PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2.

1993 • 46 citations

cDNA Cloning and Characterization of a Cek7 Receptor Protein-tyrosine Kinase Ligand That Is Identical to the Ligand (ELF-1) for the Mek-4 and Sek Receptor Protein-tyrosine Kinases

1995 • 37 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1995 • 35 citations

Cek5, a Tyrosine Kinase of the Eph Subclass, Is Activated during Neural Retina Differentiation

1994 • 30 citations

Characterization of Elk, a Brain-Specific Receptor Tyrosine Kinase

1991 • 16 citations

The bride of sevenless and sevenless interaction: internalization of a transmembrane ligand

1992 • 5 citations

Biological and Biochemical Activities of a Chimeric Epidermal Growth Factor-Elk Receptor Tyrosine Kinase

1993 • 4 citations