Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals

1995 • 481 citations

Specific human cellular immunity to bcr-abl oncogene-derived peptides

1996 • 300 citations

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

1985 • 266 citations

Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: role of polymerase chain reaction in predicting relapse

1991 • 265 citations

BCR/ABL P210 and P190 cause distinct leukemia in transgenic mice

1995 • 224 citations

Specific binding of leukemia oncogene fusion protein peptides to HLA class I molecules

1995 • 193 citations

The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript

1986 • 192 citations

Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies

1983 • 190 citations

Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.

1993 • 190 citations

T-cell immunity to the joining region of p210BCR-ABL protein.

1992 • 184 citations

The ABL-BCR fusion gene is expressed in chronic myeloid leukemia

1993 • 183 citations

The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia.

1987 • 179 citations

Human dendritic cell differentiation pathway from CD34+ hematopoietic precursor cells

1996 • 175 citations

Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia

1992 • 145 citations

Detection of two alternative bcr/abl mRNA junctions and minimal residual disease in Philadelphia chromosome positive chronic myelogenous leukemia by polymerase chain reaction

1989 • 117 citations

Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a study of 64 patients

1993 • 115 citations

Automated multiple peptide synthesis.

1992 • 108 citations

Consistent amounts of acute leukemia-associated P190BCR/ABL transcripts are expressed by chronic myelogenous leukemia patients at diagnosis

1996 • 106 citations

Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones. A novel potentially immunoregulatory T-T cell interaction in man.

1990 • 95 citations

Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice

1995 • 88 citations

Detection by enzymatic amplification of bcr-abl mRNA in peripheral blood and bone marrow cells of patients with chronic myelogenous leukemia

1989 • 72 citations

AMycobacterium leprae-Specific Human T Cell Epitope Cross-Reactive with an HLA-DR2 Peptide

1988 • 67 citations

T cell immunity to the joining region of p210^ protein.

1992 • 67 citations

Clonal development and karyotype evolution during leukemogenesis of BCR/ABL transgenic mice

1992 • 65 citations

Potential immunogenicity of oncogene and tumor suppressor gene products

1993 • 48 citations

PCR-Based Rapid Detection of the Philadelphia-Chromosome in Chronic Myelogenous and Acute Lymphoblastic Leukemia

1991 • 4 citations