Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Acute leukaemia in bcr/abl transgenic mice

1990 • 701 citations

Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

1983 • 699 citations

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1990 • 535 citations

A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia

1987 • 448 citations

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1987 • 405 citations

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1990 • 371 citations

Unique Forms of the abl Tyrosine Kinase Distinguish Ph ¹ -Positive CML from Ph ¹ -Positive ALL

1987 • 344 citations

A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia

1987 • 278 citations

Chronic myelogenous leukemia: recent advances

1985 • 247 citations

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1992 • 234 citations

Platelet-Derived Growth Factor (PDGF)-Dependent Association of Phospholipase C-γ with the PDGF Receptor Signaling Complex

1990 • 204 citations

The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript

1986 • 192 citations

Chronic myelogenous leukemia: recent advances

1985 • 190 citations

Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.

1993 • 158 citations

Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.

1991 • 126 citations

A bcr-v-abl oncogene induces lymphomas in transgenic mice.

1989 • 125 citations

Blast crisis in a murine model of chronic myelogenous leukemia.

1991 • 119 citations

Mutations of the p53 gene in lymphoid leukemia

1991 • 104 citations

Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia

1987 • 102 citations

Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

1991 • 89 citations

Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex.

1990 • 86 citations

Activation of the abl oncogene in murine and human leukemias

1985 • 66 citations

Clonal development and karyotype evolution during leukemogenesis of BCR/ABL transgenic mice

1992 • 65 citations

Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.

1992 • 63 citations

Restricted oncogenicity of BCR/ABL p190 in transgenic mice.

1992 • 58 citations

Molecular Pathogenesis of Ph-Positive Leukemias

1989 • 48 citations

CML-T1: a cell line derived from T-lymphocyte acute phase of chronic myelogenous leukemia

1989 • 27 citations

BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets

1993 • 23 citations

Mutations of the p53 gene in lymphoid leukemia

1991 • 8 citations

Molecular Pathogenesis Of Ph-Positive Leukemias

1989 • 7 citations