Rox1 mediated repression. Oxygen dependent repression in yeast.

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1999 • 4,973 citations

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.

1993 • 1,441 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium

1953 • 551 citations

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1990 • 507 citations

Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex

1995 • 469 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

1991 • 452 citations

Anaerobic nutrition of saccharomyces cerevisiae. II. Unsaturated fatty and requirement for growth in a defined medium

1954 • 391 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters.

1995 • 258 citations

DNA damage and cell cycle regulation of ribonucleotide reductase

1993 • 241 citations

Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix.

1992 • 218 citations

Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.

1991 • 203 citations

Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae.

1987 • 192 citations

The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

1994 • 190 citations

Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4.

1992 • 160 citations

The Groucho/Transducin-like Enhancer of split Transcriptional Repressors Interact with the Genetically Defined Amino-terminal Silencing Domain of Histone H3

1997 • 149 citations

The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif.

1993 • 142 citations

The Cyc8 (Ssn6)-Tup1 Corepressor Complex Is Composed of One Cyc8 and Four Tup1 Subunits

1996 • 132 citations

ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae.

1988 • 121 citations

Transcriptional repression directed by the yeast α2 protein in vitro

1994 • 118 citations

A Complex Composed of Tup1 and Ssn6 Represses Transcription in Vitro

1997 • 103 citations

Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae.

1995 • 100 citations

HAP1 and ROX1 Form a Regulatory Pathway in the Repression of HEM13 Transcription in Saccharomyces cerevisiae

1992 • 100 citations

Chromatin-mediated transcription repression in yeast

1995 • 94 citations

The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation.

1994 • 93 citations

Residues in the WD Repeats of Tup1 Required for Interaction with α2

1997 • 90 citations

Isolation and characterization of the Saccharomyces cerevisiae SUT1 gene involved in sterol uptake

1995 • 77 citations

Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor

1993 • 74 citations

A hypoxic consensus operator and a constitutive activation region regulate the ANB1 gene of Saccharomyces cerevisiae.

1990 • 71 citations

Mutational Analysis of Rox1, a DNA-Bending Repressor of Hypoxic Genes in Saccharomyces cerevisiae

1995 • 69 citations

Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae.

1993 • 67 citations

HAP1 is nuclear but is bound to a cellular factor in the absence of heme.

1994 • 61 citations

Mot3, a Zn Finger Transcription Factor That Modulates Gene Expression and Attenuates Mating Pheromone Signaling in Saccharomyces cerevisiae

1998 • 58 citations

Groucho/transducin-like Enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms

1998 • 57 citations

The DAN1 gene of S. cerevisiae is regulated in parallel with the hypoxic genes, but by a different mechanism

1997 • 55 citations

Cloning of the yeast SFL2 gene: its disruption results in pleiotropic phenotypes characteristic for tup1 mutants

1990 • 49 citations

Mutational Analysis of the Tup1 General Repressor of Yeast

1998 • 43 citations

Approaches to the Study of Rox1 Repression of the Hypoxic Genes in the YeastSaccharomyces cerevisiae

1997 • 37 citations

Characterization of the DNA binding and bending HMG domain of the yeast hypoxic repressor Rox1

1999 • 36 citations

The Anatomy of a Hypoxic Operator in Saccharomyces cerevisiae

1998 • 35 citations

Identification and Analysis of Mot3, a Zinc Finger Protein That Binds to the Retrotransposon Ty Long Terminal Repeat (δ) in Saccharomyces cerevisiae

1998 • 29 citations

Identification of an Upstream Repressor Site Controlling the Expression of an Anaerobic Gene (ANB1) in Saccharomyces cerevisiae

1989 • 25 citations