Approaches to the Study of Rox1 Repression of the Hypoxic Genes in the YeastSaccharomyces cerevisiae

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1990 • 85,659 citations

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New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Methods in Yeast Genetics: A Laboratory Course Manual

1990 • 1,922 citations

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1987 • 1,449 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium

1953 • 551 citations

Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex

1995 • 469 citations

Biosynthesis of heme and chlorophylls

1990 • 465 citations

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 462 citations

The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene

1990 • 409 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

Anaerobic nutrition of saccharomyces cerevisiae. II. Unsaturated fatty and requirement for growth in a defined medium

1954 • 391 citations

Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.

1991 • 359 citations

Functional dissection and sequence of yeast HAP1 activator

1989 • 309 citations

Heme binds to a short sequence that serves a regulatory function in diverse proteins.

1995 • 285 citations

Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase

1991 • 243 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

A third ADP/ATP translocator gene in yeast.

1990 • 205 citations

The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

1994 • 190 citations

Biochemical and Clinical Aspects of Oxygen

1979 • 186 citations

The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif.

1993 • 142 citations

CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast

1988 • 128 citations

ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae.

1988 • 121 citations

Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase.

1988 • 119 citations

Transcriptional repression directed by the yeast α2 protein in vitro

1994 • 118 citations

Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11).

1992 • 115 citations

Biochemical and clinical aspects of oxygen

1981 • 103 citations

Regulation of Synthesis of Catalases and Iso-1-cytochrome c in Saccharomyces cerevisiae by Glucose, Oxygen and Heme

2005 • 103 citations

Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae.

1995 • 100 citations

HAP1 and ROX1 Form a Regulatory Pathway in the Repression of HEM13 Transcription in Saccharomyces cerevisiae

1992 • 100 citations

Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes.

1988 • 99 citations

Inverse regulation of the yeast COX5 genes by oxygen and heme.

1989 • 92 citations

Positive and negative transcriptional control by heme of genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae.

1989 • 90 citations

Constitutive expression of the yeast HEM1 gene is actually a composite of activation and repression.

1987 • 85 citations

HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae.

1992 • 79 citations

The expression in yeast of the Escherichia coli galK gene on CYCI :: galK fusion plasmids

1983 • 74 citations

Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor

1993 • 74 citations

Mutational Analysis of Rox1, a DNA-Bending Repressor of Hypoxic Genes in Saccharomyces cerevisiae

1995 • 69 citations

Negative control of yeast coproporphyrinogen oxidase synthesis by heme and oxygen.

1986 • 67 citations

Elements Involved in Oxygen Regulation of the Saccharomyces Cerevisiae CYC7 Gene

1987 • 66 citations

A yeast protein with homology to the β-subunit of G proteins is involved in control of heme-regulated and catabolite-repressed genes

1991 • 65 citations

The ANB1 locus of Saccharomyces cerevisiae encodes the protein synthesis initiation factor eIF-4D.

1990 • 61 citations

Negative Regulation of the Saccharomyces cerevisiae ANB1 Gene by Heme, as Mediated by the ROX1 Gene Product

1986 • 56 citations

Elements involved in oxygen regulation of the Saccharomyces cerevisiae CYC7 gene.

1987 • 44 citations

Toxicity of 2-Deoxygalactose to Saccharomyces cerevisiae Cells Constitutively Synthesizing Galactose-Metabolizing Enzymes

1984 • 44 citations

CYP1 (HAP1) is a determinant effector of alternative expression of heme-dependent transcription in yeast

1991 • 38 citations

Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesizing galactose-metabolizing enzymes.

1984 • 31 citations

Negative regulation of the Saccharomyces cerevisiae ANB1 gene by heme, as mediated by the ROX1 gene product.

1986 • 31 citations

Functional analysis of the zinc cluster domain of the CYP1 (HAP1) complex regulator in heme-sufficient and heme-deficient yeast cells

1994 • 24 citations

Methods in yeast genetics: A laboratory course manual

1991 • 17 citations

A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.

1994 • 16 citations