Molecular Structure and Function of Microtubule-Associated Proteins

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

1986 • 3,430 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

1986 • 1,709 citations

The distribution of tau in the mammalian central nervous system.

1985 • 1,518 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

1989 • 989 citations

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

1988 • 920 citations

Movement of microtubules by single kinesin molecules

1989 • 878 citations

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

1977 • 878 citations

Phosphorylation affects the ability of tau protein to promote microtubule assembly.

1984 • 852 citations

Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

1977 • 834 citations

Tracking kinesin-driven movements with nanometre-scale precision

1988 • 816 citations

Tau protein function in living cells.

1986 • 727 citations

DEFECTIVE BRAIN MICROTUBULE ASSEMBLY IN ALZHEIMER'S DISEASE

1986 • 704 citations

The Primary Structure and Heterogeneity of Tau Protein from Mouse Brain

1988 • 671 citations

A novel brain ATPase with properties expected for the fast axonal transport motor

1985 • 604 citations

Microtubule-Associated Proteins: Their Potential Role in Determining Neuronal Morphology

1988 • 599 citations

Developmentally regulated expression of specific tau sequences

1989 • 589 citations

Dynein: A Protein with Adenosine Triphosphatase Activity from Cilia

1965 • 579 citations

Structural characterization of the core of the paired helical filament of Alzheimer disease.

1988 • 566 citations

MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties.

1987 • 563 citations

Microtubule-Associated Proteins

1986 • 559 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

Selective localization of messenger RNA for cytoskeletal protein MAP2 in dendrites

1988 • 546 citations

Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2

1986 • 535 citations

The periodic association of MAP2 with brain microtubules in vitro.

1979 • 510 citations

Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors.

1985 • 506 citations

Phosphorylated Tau Protein Is Integrated into Paired Helical Filaments in Alzheimer's Disease1

1986 • 504 citations

The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

1989 • 500 citations

Epitopes that span the tau molecule are shared with paired helical filaments

1988 • 494 citations

Myosin subfragment-1 is sufficient to move actin filaments in vitro

1987 • 484 citations

Tau Consists of a Set of Proteins with Repeated C-Terminal Microtubule-Binding Domains and Variable N-Terminal Domains

1989 • 478 citations

Microtubule-Associated Protein MAP2 Shares a Microtubule Binding Motif with Tau Protein

1988 • 476 citations

The microtubule binding domain of tau protein

1989 • 472 citations

Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro

1985 • 463 citations

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

1989 • 460 citations

Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.

1985 • 440 citations

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules

1989 • 436 citations

Video‐enhanced contrast, differential interference contrast (AVEC‐DIC) microscopy: A new method capable of analyzing microtubule‐related motility in the reticulopodial network of allogromia laticollaris

1981 • 419 citations

Identification of the major multiphosphorylation site in mammalian neurofilaments.

1988 • 394 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

MAP2 and tau segregate into dendritic and axonal domains after the elaboration of morphologically distinct neurites: an immunocytochemical study of cultured rat cerebrum

1987 • 363 citations

Tau proteins: the molecular structure and mode of binding on microtubules.

1988 • 363 citations

Single microtubules from squid axoplasm support bidirectional movement of organelles

1985 • 363 citations

The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts

1988 • 359 citations

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

1989 • 354 citations

Fast Axonal Transport in Squid Giant Axon

1982 • 347 citations

Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon

1985 • 346 citations

The car☐yl third of tau is tightly bound to paired helical filaments

1988 • 342 citations

A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end.

1987 • 338 citations

Dynein is the motor for retrograde axonal transport of organelles.

1989 • 334 citations

Fast Axonal Transport in Extruded Axoplasm from Squid Giant Axon

1982 • 333 citations

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains.

1989 • 321 citations

Cytoplasmic dynein is a minus end-directed motor for membranous organelles

1989 • 313 citations

Fractionation of Brain Microtubule‐Associated Proteins

1978 • 310 citations

Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family.

1989 • 306 citations

Video image processing greatly enhances contrast, quality, and speed in polarization-based microscopy.

1981 • 303 citations

Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle

1985 • 301 citations

Multiple sites of alternative splicing of the rat fibronectin gene transcript.

1987 • 299 citations

The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau.

1989 • 294 citations

Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon

1985 • 289 citations

Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide

1988 • 284 citations

Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau

1989 • 281 citations

Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin-dependent kinase and modulated by phospholipids.

1987 • 264 citations

Microtubule-associated protein 1C from brain is a two-headed cytosolic dynein

1988 • 263 citations

Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

1989 • 261 citations

Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease.

1989 • 255 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2)

1981 • 243 citations

MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS

1989 • 241 citations

Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system.

1984 • 238 citations

Kinesin ATPase: rate-limiting ADP release.

1988 • 238 citations

Heterogeneity of microtubule-associated protein 2 during rat brain development.

1984 • 236 citations

Structure and phosphorylation of microtubule-associated protein 2 (MAP 2).

1980 • 235 citations

A microtubule-binding protein associated with membranes of the Golgi apparatus.

1986 • 234 citations

Identification of globular mechanochemical heads of kinesin

1989 • 231 citations

Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans

1987 • 218 citations

Common and distinct tubulin binding sites for microtubule-associated proteins.

1986 • 216 citations

Bovine brain kinesin is a microtubule-activated ATPase.

1986 • 215 citations

A Novel 58-kDa Protein Associates with the Golgi Apparatus and Microtubules

1989 • 214 citations

Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase.

1984 • 213 citations

MAP5: A novel brain microtubule-associated protein under strong developmental regulation

1986 • 210 citations

A latent adenosine triphosphatase form of dynein 1 from sea urchin sperm flagella.

1979 • 208 citations

Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor.

1983 • 207 citations

Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton.

1985 • 197 citations

Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation.

1989 • 191 citations

High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins.

1984 • 191 citations

The purification of tau protein and the occurrence of two phosphorylation states of tau in brain.

1984 • 189 citations

Interactions between the microtubule-associated tau proteins and S100b regulate tau phosphorylation by the Ca2+/calmodulin-dependent protein kinase II.

1988 • 189 citations

Interactions of synapsin I with small synaptic vesicles: distinct sites in synapsin I bind to vesicle phospholipids and vesicle proteins.

1989 • 187 citations

Microtubule-associated protein 1B: Molecular structure, localization, and phosphorylation-dependent expression in developing neurons

1989 • 185 citations

Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP

1985 • 184 citations

MAP2 is a component of crossbridges between microtubules and neurofilaments in the neuronal cytoskeleton: quick-freeze, deep-etch immunoelectron microscopy and reconstitution studies

1988 • 182 citations

Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains.

1988 • 180 citations

The distribution, abundance and subcellular localization of kinesin.

1989 • 179 citations

The role of kinesin and other soluble factors in organelle movement along microtubules.

1988 • 179 citations

The quaternary structure of bovine brain kinesin.

1988 • 178 citations

Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin

1989 • 174 citations

Two Separate 18-Amino Acid Domains of Tau Promote the Polymerization of Tubulin

1989 • 167 citations

In situ localization of microtubule-associated protein mRNA in the developing and adult rat brain

1989 • 165 citations

Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.

1984 • 164 citations

Formation of membrane networks in vitro by kinesin-driven microtubule movement.

1988 • 163 citations

Microtubule assembly using the microtubule‐associated protein MAP‐2 prepared in defined states of phosphorylation with protein kinase and phosphatase

1983 • 163 citations

Cytoskeletal architecture and immunocytochemical localization of microtubule-associated proteins in regions of axons associated with rapid axonal transport: the beta,beta'-iminodipropionitrile-intoxicated axon as a model system.

1985 • 163 citations

Modification of microtubule steady-state dynamics by phosphorylation of the microtubule-associated proteins.

1981 • 160 citations

Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells.

1988 • 160 citations

Bidirectional pigment granule movements of melanophores are regulated by protein phosphorylation and dephosphorylation

1986 • 157 citations

Different forms of microtubule-associated protein 2 are encoded by separate mRNA transcripts.

1988 • 157 citations

A dynein‐like protein associated with neurotubules

1974 • 154 citations

Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells.

1982 • 153 citations

A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation.

1988 • 153 citations

Characterization of the microtubule movement produced by sea urchin egg kinesin.

1987 • 153 citations

Ontogeny of microtubule-associated protein 2 in rat cerebellum: Differential expression of the doublet polypeptides

1984 • 144 citations

Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.

1987 • 144 citations

Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C).

1988 • 142 citations

Sequence of the sites phosphorylated by protein kinase C in the smooth muscle myosin light chain.

1987 • 142 citations

Nerve growth factor regulates both the phosphorylation and steady-state levels of microtubule-associated protein 1.2 (MAP1.2).

1988 • 139 citations

Synapsin I is a microtubule-bundling protein

1986 • 137 citations

Electron microscopy of map 2 (microtubule-associated protein 2)

1982 • 135 citations

A dynein‐like protein from brain

1974 • 130 citations

Structure of the dynein-1 outer arm in sea urchin sperm flagella. I. Analysis by separation of subunits.

1982 • 129 citations

A microtubule-associated protein (MAP1) which is expressed at elevated levels during development of the rat cerebellum.

1985 • 125 citations

Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated .tau. proteins and inhibition of phosphorylation of .tau. proteins by protein kinase C

1987 • 122 citations

A Common Amino Acid Sequence in 190-kDa Microtubule-associated Protein and Tau for the Promotion of Microtubule Assembly

1989 • 121 citations

Drosophila kinesin: characterization of microtubule motility and ATPase.

1988 • 120 citations

Differential interaction of synthetic peptides from the carboxyl-terminal regulatory domain of tubulin with microtubule-associated proteins.

1988 • 120 citations

Interaction of microtubule-associated protein 2 with actin filaments

1986 • 119 citations

Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2

1989 • 118 citations

Characterization of brain microtubule proteins prepared by selective removal of mitochondrial and synaptosomal components.

1979 • 116 citations

Characterization of synapsin I fragments produced by cysteine-specific cleavage: a study of their interactions with F-actin.

1989 • 115 citations

The calmodulin‐binding protein in microtubules is tau factor

1981 • 112 citations

Brain dynein crossbridges microtubules into bundles

1989 • 112 citations

The multiple phosphorylation of the microtubule-associated protein MAP2 controls the MAP2: tubulin interaction

1984 • 112 citations

Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1).

1983 • 112 citations

Specific cleavage of dynein heavy chains by ultraviolet irradiation in the presence of ATP and vanadate.

1986 • 111 citations

Quantitative analysis of sea urchin egg kinesin-driven microtubule motility

1989 • 111 citations

Correlation between the ATPase and microtubule translocating activities of sea urchin egg kinesin

1987 • 110 citations

High-Mr microtubule-associated proteins: properties and functions

1989 • 107 citations

Localization of kinesin in cultured cells.

1988 • 107 citations

Dynein-like Mg2+-ATPase in mitotic spindles isolated from sea urchin embryos (Strongylocentrotus droebachiensis).

1980 • 105 citations

A 70‐Kilodalton Microtubule‐Associated Protein (MAP2c), Related to MAP2

1988 • 104 citations

Nucleotide requirements for anaphase chromosome movements in permeabilized mitotic cells: Anaphase B but not anaphase a requires ATP

1982 • 103 citations

Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo.

1980 • 102 citations

An ATPase with properties expected for the organelle motor of the giant amoeba, Reticulomyxa

1988 • 99 citations

The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptide.

1989 • 98 citations

Isolation of a 45-kDa Fragment from the Kinesin Heavy Chain with Enhanced ATPase and Microtubule-binding Activities

1989 • 96 citations

Physicochemical characterization of the heat-stable microtubule-associated protein MAP2

1986 • 96 citations

Kinesin from pig brain studied by electron microscopy

1987 • 96 citations

Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1.

1988 • 94 citations

Binding of gizzard smooth muscle myosin subfragment-1 to actin in the presence and absence of adenosine 5'-triphosphate

1983 • 94 citations

Preparation of microtubules from rat liver and testis: Cytoplasmic dynein is a major microtubule associated protein

1989 • 93 citations

Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin.

1988 • 92 citations

Binding of microtubule-associated protein 2 and tau to the intermediate filament reassembled from neurofilament 70-kDa subunit protein. Its regulation by calmodulin.

1986 • 91 citations

The identification of a dynein ATPase in unfertilized sea urchin eggs

1980 • 91 citations

Calmodulin inhibits interaction of actin with MAP2 and Tau, two major microtubule-associated proteins.

1985 • 91 citations

Copurification of kinesin polypeptides with microtubule‐stimulated Mg‐ATPase activity and kinetic analysis of enzymatic properties

1989 • 90 citations

Studies on ATPase activity of sea urchin eggs and the isolated mitotic apparatus

1968 • 90 citations

Translocation of vesicles from squid axoplasm on flagellar microtubules

1985 • 90 citations

MAP 4: a microtubule-associated protein specific for a subset of tissue microtubules.

1984 • 90 citations

The mechanism and regulation of fast axonal transport

1989 • 90 citations

Separation of the different microtubule-associated tau protein species from bovine brain and their mode II phosphorylation by Ca2+/phospholipid-dependent protein kinase C.

1987 • 87 citations

Numerous phosphates of microtubule-associated protein 2 in living rat brain.

1987 • 87 citations

Molecular cloning and expression of flagellar radial spoke and dynein genes of Chlamydomonas.

1986 • 87 citations

A microtubule-associated protein in Drosophila melanogaster: identification, characterization, and isolation of coding sequences.

1986 • 87 citations

Brain-specific expression of MAP2 detected using a cloned cDNA probe.

1986 • 84 citations

Colocalization of microtubule-associated protein 1A and microtubule-associated protein 2 on neuronal microtubules in situ revealed with double-label immunoelectron microscopy.

1987 • 84 citations

Sertoli cell processes have axoplasmic features: an ordered microtubule distribution and an abundant high molecular weight microtubule-associated protein (cytoplasmic dynein).

1988 • 83 citations

Purified protein kinase C phosphorylates microtubule-associated protein 2.

1986 • 82 citations

Immunological characterization of microtubule‐associated proteins specific for the immature brain

1985 • 81 citations

Conservation of microtubule associated proteins. Isolation and characterization of tau and the high molecular weight microtubule associated protein from chicken brain and from mouse fibroblasts and comparison to the corresponding mammalian brain proteins.

1979 • 81 citations

The molecular structure of microtubule-associated protein 1A (MAP1A) in vivo and in vitro. An immunoelectron microscopy and quick-freeze, deep- etch study

1987 • 78 citations

Protein‐kinase‐C‐catalyzed phosphorylation of the microtubule‐binding domain of microtubule‐associated protein 2 inhibits its ability to induce tubulin polymerization

1988 • 78 citations

MAP3: characterization of a novel microtubule-associated protein.

1985 • 75 citations

Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles.

1987 • 73 citations

Structure and elasticity of microtubule-associated protein tau

1988 • 72 citations

Purification and characterization of a 190-kD microtubule-associated protein from bovine adrenal cortex.

1986 • 70 citations

Cloning of a cDNA Encoding MAP1B in Rat Brain: Regulation of mRNA Levels During Development

1989 • 69 citations

Abnormal tau species are produced during Alzheimer's disease neurodegenerating process

1989 • 67 citations

A monoclonal antibody that cross-reacts with phosphorylated epitopes on two microtubule-associated proteins and two neurofilament polypeptides.

1986 • 66 citations

Microtubule-binding domain of tau proteins.

1988 • 66 citations

Identification of a MAP 2-like ATP-binding protein associated with axoplasmic vesicles that translocate on isolated microtubules.

1986 • 65 citations

Interaction between kinesin, microtubules, and microtubule‐associated protein 2

1989 • 63 citations

Regulation of pigment organelle translocation. I. Phosphorylation of the organelle-associated protein p57.

1986 • 63 citations

Regulation of pigment organelle translocation. II. Participation of a cAMP-dependent protein kinase.

1986 • 62 citations

Monoclonal antibodies to dynein subunits reveal the existence of cytoplasmic antigens in sea urchin egg.

1984 • 61 citations

270K microtubule-associated protein cross-reacting with anti-MAP2 IgG in the crayfish peripheral nerve axon.

1986 • 61 citations

Cytoplasmic Dynein of the Sea Urchin Egg.1 II. Purification, Characterization and Interactions with Microtubules and Ca-Calmodulin

1983 • 61 citations

Interactions of dynein arms with b subfibers of Tetrahymena cilia: quantitation of the effects of magnesium and adenosine triphosphate.

1980 • 60 citations

Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules.

1982 • 60 citations

The molecular structure of adrenal medulla kinesin

1989 • 59 citations

Inhibition of proteolysis blocks anterograde-retrograde conversion of axonally transported vesicles

1988 • 58 citations

Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain.

1988 • 58 citations

Microtubule Gelation-Contraction: Essential Components and Relation to Slow Axonal Transport

1987 • 57 citations

Tyrosine phosphorylation by the epidermal growth factor receptor kinase induces functional alterations in microtubule-associated protein 2.

1987 • 57 citations

18 kDa microtubule‐associated protein: identification as a new light chain (LC‐3) of microtubule‐associated protein 1 (MAP‐1)

1987 • 57 citations

Microtubule‐Associated Proteins in the Developing Brain

1986 • 55 citations

Cytoplasmic dynein-like ATPase cross-links microtubules in an ATP-sensitive manner.

1984 • 54 citations

Taxol-induced bundling of brain-derived microtubules.

1984 • 54 citations

A cloned cDNA encoding MAP1 detects a single copy gene in mouse and a brain-abundant RNA whose level decreases during development.

1986 • 54 citations

Inhibition of spindle elongation in permeabilized mitotic cells by erythro-9-[3-(2-hydroxynonyl)] adenine

1982 • 53 citations

Isolation of rat liver microtubule-associated proteins. Evidence for a family of microtubule-associated proteins with molecular mass of around 200,000 which distribute widely among mammalian cells.

1988 • 53 citations

Epidermal growth factor induces rapid centrosomal separation in HeLa and 3T3 cells.

1982 • 52 citations

Microheterogeneity of microtubule-associated proteins, MAP-1 and MAP-2, and differential phosphorylation of individual subcomponents.

1985 • 52 citations

High-molecular-weight microtubule associated proteins (MAPS): a ubiquitous family of cytoskeletal connecting links

1985 • 52 citations

A distinct form of tau is selectively incorporated into Alzheimer's paired helical filaments

1989 • 50 citations

Partial Sequence of MAP2 in the Region of a Shared Epitope with Alzheimer Neuronbrillary Tangles

1988 • 50 citations

Active sliding between cytoplasmic microtubules

1987 • 49 citations

Reinvestigation of the sulfhydryl reactivity in bovine brain S100b (.beta..beta.) protein and the microtubule-associated .tau. proteins. Calcium stimulates disulfide cross-linking between S100b .beta.-subunit and the microtubule-associated .tau.(2) protein

1988 • 49 citations

Anti-idiotypic antibodies that react with microtubule-associated proteins are present in the sera of rabbits immunized with synthetic peptides from tubulin's regulatory domain.

1988 • 49 citations

Cultured neurons contain a variety of microtubule-associated proteins

1985 • 45 citations

Identification of high molecular weight microtubule-associated proteins in anterior pituitary tissue and cells using taxol-dependent purification combined with microtubule-associated protein specific antibodies

1985 • 44 citations

Purification of high‐M_r microtubule proteins MAP1 and MAP2

1981 • 44 citations

Identification of a kinesin-like microtubule-based motor protein in Dictyostelium discoideum.

1989 • 43 citations

Cytoskeletal architecture of isolated mitotic spindle with special reference to microtubule-associated proteins and cytoplasmic dynein.

1985 • 43 citations

Stable complexes of axoplasmic vesicles and microtubules: protein composition and ATPase activity.

1986 • 43 citations

Binding of dynein 21 S ATPase to microtubules. Effects of ionic conditions and substrate analogs.

1981 • 43 citations

Modulation of mRNA for microtubule-associated proteins during brain development.

1982 • 43 citations

Fast axonal transport of foreign synaptic vesicles in squid axoplasm.

1985 • 42 citations

A latent activity dynein-like cytoplasmic magnesium adenosine triphosphatase.

1985 • 42 citations

Erythrocyte microtubule assembly in vitro. Determination of the effects of erythrocyte tau, tubulin isoforms, and tubulin oligomers on erythrocyte tubulin assembly, and comparison with brain microtubule assembly.

1985 • 42 citations

Characterization of microtubule-associated proteins isolated from bovine adrenal gland

1986 • 41 citations

Analysis of the microtubule-binding domain of MAP-2.

1985 • 41 citations

Interactions of cytoplasmic granules with microtubules in human neutrophils.

1989 • 40 citations

Identification of a lysosome membrane protein which could mediate ATP-dependent stable association of lysosomes to microtubules

1989 • 40 citations

Purification and characterization of kinesin from bovine adrenal medulla.

1988 • 40 citations

Dynein isoforms in sea urchin eggs.

1988 • 38 citations

A novel microtubule-associated protein from mammalian nerve shows ATP-sensitive binding to microtubules.

1986 • 37 citations

A microtubule-activated ATPase from sea urchin eggs, distinct from cytoplasmic dynein and kinesin.

1986 • 37 citations

Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport

1989 • 35 citations

Limited chymotryptic digestion of bovine adrenal 190,000-Mr microtubule-associated protein and preparation of a 27,000-Mr fragment which stimulates microtubule assembly.

1987 • 34 citations

Antibodies to synthetic peptides from the tubulin regulatory domain interact with tubulin and microtubules.

1988 • 33 citations

Identification of a 34-kD polypeptide as a light chain of microtubule-associated protein-1 (MAP-1) and its association with a MAP-1 peptide that binds to microtubules.

1986 • 32 citations

Evidence that the 116 kDa component of kinesin binds and hydrolyses ATP

1987 • 32 citations

Extensive purification from Acanthamoeba castellanii of a microtubule-dependent translocator with microtubule-activated Mg2+-ATPase activity.

1987 • 31 citations

Microtubule-associated proteins MAP5 and MAP1x: closely related components of the neuronal cytoskeleton with different cytoplasmic distributions in the developing brain

1989 • 31 citations

ATP-induced gelation--contraction of microtubules assembled in vitro.

1984 • 31 citations

The calmodulin-binding domain on microtubule-associated protein 2.

1984 • 30 citations

Melanoma dynein: evidence that dynein is a general "motor" for microtubule-associated cell motilities.

1987 • 30 citations

Neuraxin, a novel putative structural protein of the rat central nervous system that is immunologically related to microtubule-associated protein 5.

1989 • 30 citations

A squid dynein isoform promotes axoplasmic vesicle translocation.

1989 • 29 citations

Comparison of the effects of microtubule-associated protein 2 and tau on the packing density of in vitro assembled microtubules.

1987 • 28 citations

Identity and origin of the ATPase activity associated with neuronal microtubules. II. Identification of a 50,000-dalton polypeptide with ATPase activity similar to F-1 ATPase from mitochondria.

1983 • 28 citations

Homology of egg and flagellar dynein. Comparison of ATP-binding sites and primary structure.

1986 • 27 citations

The 28,000 Mr microtubule-binding domain of microtubule-associated protein-2 also contains a neurofilament-binding site

1987 • 25 citations

More efficient solar cells

1990 • 24 citations

Differential Structure and Distribution of the High Molecular Weight Brain Microtubule‐Associated Proteins, MAP‐1 and MAP‐2

1986 • 22 citations

Analysis of the spatial organization of microtubule-associated proteins.

1986 • 22 citations

Characterization of mitotic motors by their relative sensitivity to amp-pnp

1989 • 22 citations

Complete sequence of a cDNA encoding moinc MAP2

1988 • 21 citations

"Buttonin," a unique button-shaped microtubule-associated protein (75 kD) that decorates spindle microtubule surface hexagonally.

1987 • 18 citations

Molecular Aspects of MAP‐1 and MAP‐2: Microheterogeneity, in Vitro Localization and Distribution in Neuronal and Nonneuronal Cellsa

1986 • 17 citations

Isolation of dynein heavy chain cDNAs from trout testis which predict an extensive carboxyl-terminal alpha-helical coiled-coil domain.

1989 • 16 citations

Molecular analysis of the alpha and beta dynein genes of Chlamydomonas reinhardtii

1989 • 16 citations

Binding of kinesin to stress fibers in fibroblasts under condition of microtubule depolymerization

1989 • 14 citations

Binding specificities of purified porcine brain alpha- and beta-tubulin subunits and of microtubule-associated proteins 1 and 2 examined by electron microscopy and solid-phase binding assays.

1987 • 13 citations

An antiserum to the sea urchin 20 S egg dynein reacts with embryonic ciliary dynein but it does not react with the mitotic apparatus

1986 • 12 citations

Ionic strength-dependent isoforms of sea urchin egg dynein.

1988 • 12 citations

Microtubule‐associated protein tau Identification of a novel peptide from bovine brain

1989 • 12 citations

Microtubule‐associated proteins present in different developmental stages ofDrosophila melanogaster

1987 • 12 citations

Single-shot cloning of multiple cDNAs coding for a set of related microtubule-associated proteins

1988 • 11 citations

Substructure of sea urchin egg cytoplasmic dynein

1987 • 10 citations

Microtubule gelation‐contraction in vitro and its relationship to component a of slow axonal transport

1988 • 9 citations

Vesikin, a vesicle associated ATPase from squid axoplasm and optic lobe, has characteristics in common with vertebrate brain MAP 1 and MAP 2

1988 • 8 citations

‘Corkscrewing’, as evidence for force generation within a detergent-extracted microtubule translocation system from insect ovaries

1989 • 6 citations

Characterization of a microtubule-stimulated adenosine triphosphatase activity associated with microtubule gelation-contraction

1988 • 5 citations

Structural Differences of Microtubule Associated Proteins from Brain Probed by Tryptic Peptide Mapping1

1986 • 3 citations

Bull sperm 19S dynein polymerizes brain tubulin into microtubules

1987 • 3 citations

Isolation of a Ca2+-protease resistant high Mr microtubule binding protein from mammalian brain: Characterization of properties partially expected for a dynein-like molecule

1987 • 2 citations

Deleted Work

1955 • 0 citations