Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

A protein factor essential for microtubule assembly.

1975 • 2,863 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

1977 • 878 citations

Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

1977 • 834 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro.

1975 • 535 citations

AXON GROWTH: ROLES OF MICROFILAMENTS AND MICROTUBULES

1970 • 522 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

Regulation of Axon Formation by Clonal Lines of a Neural Tumor

1970 • 480 citations

Unpolymerized tubulin modulates the level of tubulin mRNAs

1981 • 392 citations

10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin.

1984 • 388 citations

Single microtubules from squid axoplasm support bidirectional movement of organelles

1985 • 363 citations

Mechanisms of regulating tubulin synthesis in cultured mammalian cells

1979 • 359 citations

Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B.

1984 • 352 citations

Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon

1985 • 346 citations

Fractionation of Brain Microtubule‐Associated Proteins

1978 • 310 citations

MICROTUBULES AND FILAMENTS IN THE AXONS AND ASTROCYTES OF EARLY POSTNATAL RAT OPTIC NERVES

1967 • 284 citations

Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells.

1981 • 239 citations

A polymer-dependent increase in phosphorylation of beta-tubulin accompanies differentiation of a mouse neuroblastoma cell line.

1985 • 237 citations

Heterogeneity of microtubule-associated protein 2 during rat brain development.

1984 • 236 citations

Interconversion of metaphase and interphase microtubule arrays, as studied by the injection of centrosomes and nuclei into Xenopus eggs.

1984 • 225 citations

Cholinergic metabolism and synapse formation by a rat nerve cell line.

1977 • 217 citations

Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor.

1983 • 207 citations

Multiple forms of the nerve growth factor protein and its subunits

1968 • 179 citations

Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.

1984 • 164 citations

Changes in composition and activity of microtubule-associated proteins during brain development

1980 • 159 citations

Arrangement of high molecular weight associated proteins on purified mammalian brain microtubules.

1977 • 155 citations

Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells.

1982 • 153 citations

Identification with cellular microtubules of one of the co-assembling microtubule-associated proteins

1979 • 148 citations

Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells.

1985 • 140 citations

The role of transcription-dependent priming in nerve growth factor promoted neurite outgrowth

1982 • 130 citations

Identification of three coated vesicle components as alpha- and beta-tubulin linked to a phosphorylated 50,000-dalton polypeptide.

1983 • 128 citations

Role of the centrosome in organizing the interphase microtubule array: properties of cytoplasts containing or lacking centrosomes.

1984 • 121 citations

Physical and chemical

1966 • 113 citations

Tubulin requires an accessory protein for self assembly into microtubules

1975 • 110 citations

Cytochalasin separates microtubule disassembly from loss of asymmetric morphology.

1981 • 105 citations

Modulation of protein synthesis by nerve growth factor.

1979 • 102 citations

Fine structure of initial outgrowth of processes induced in a pheochromocytoma cell line (PC12) by nerve growth factor

1979 • 92 citations

Association of Tau Protein with Microtubules in Living Cells

1986 • 90 citations

THE ROLE OF MICROTUBULES IN THE GROWTH AND STABILIZATION OF NERVE FIBERS

1975 • 87 citations

Tubulin pools in differentiating neuroblastoma cells.

1981 • 66 citations

Microtubule‐associated protein MAP1 promotes microtubule assembly in vitro

1981 • 60 citations

Proteins from morphologically differentiated neuroblastoma cells promote tubulin polymerization.

1978 • 34 citations