BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells.

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults

1993 • 872 citations

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation.

1995 • 258 citations

APO2 ligand: a novel lethal weapon against malignant glioma?

1998 • 193 citations

Survival of Patients with Glioblastoma Multiforme is not Influenced by Altered Expression of P16, P53, EGFR, MDM2 or Bcl‐2 Genes

1998 • 180 citations

Predicting chemoresistance in human malignant glioma cells: The role of molecular genetic analyses

1998 • 171 citations

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

1996 • 170 citations

BCL-2 Family protein expression in initial and recurrent glioblastomas: modulation by radiochemotherapy

1999 • 127 citations

Tumor radiosensitivity and apoptosis

2000 • 119 citations

The Molecular and Cellular Basis of Radiosensitivity: Implications for Understanding How Normal Tissues and Tumors Respond to Therapeutic Radiation

1999 • 113 citations

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis

1999 • 112 citations

The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21 ^BAX expression

1998 • 103 citations

BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study

1998 • 78 citations

Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax

1999 • 75 citations

Overexpression of bax in human glioma cell lines

1999 • 35 citations

Accumulation of Mutant p53V143A Modulates the Growth, Clonogenicity, and Radiochemosensitivity of Malignant Glioma Cells Independent of Endogenous p53 Status

1999 • 32 citations

Irradiation induced clonogenic cell death of human malignant glioma cells does not require CD95/CD95L interactions.

2000 • 7 citations