Expression of CD27 and its ligand, CD70, on chronic lymphocytic leukemia B cells

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

IL-4 directs the development of Th2-like helper effectors.

1990 • 1,261 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

Molecular and biological characterization of a murine ligand for CD40

1992 • 1,029 citations

Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones

1991 • 1,027 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

B70 antigen is a second ligand for CTLA-4 and CD28

1993 • 907 citations

Signals and signs for lymphocyte responses

1994 • 868 citations

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

1992 • 818 citations

How B and T cells talk to each other

1994 • 659 citations

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

1991 • 554 citations

The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones.

1989 • 304 citations

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

1993 • 280 citations

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation.

1993 • 261 citations

Regulation of CD27 expression on subsets of mature T-lymphocytes.

1993 • 247 citations

The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.

1991 • 245 citations

Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells.

1992 • 183 citations

Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia cells: a possible regulatory role of TNF in the progression of the disease

1990 • 174 citations

The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activation.

1993 • 168 citations

B cells regulate expression of CD40 ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40

1994 • 157 citations

Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.

1990 • 154 citations

Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cells

1993 • 147 citations

IgM and IgG but not cytokine secretion is restricted to the CD27+ B lymphocyte subset.

1992 • 142 citations

The cloning of CD70 and its identification as the ligand for CD27.

1994 • 139 citations

CD27 expression by a distinct subpopulation of human B lymphocytes

1990 • 138 citations

Regulation of T helper cell cytokine expression: functional dichotomy of antigen‐presenting cells

1993 • 136 citations

A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells.

1990 • 133 citations

Expression and release of CD27 in human B-cell malignancies

1993 • 130 citations

CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation.

1994 • 120 citations

Elevated levels of a soluble form of the T cell activation antigen CD27 in cerebrospinal fluid of multiple sclerosis patients

1991 • 96 citations

Regulation of expression of CD27, a T cell-specific member of a novel family of membrane receptors.

1991 • 94 citations

The CD27 membrane receptor, a lymphocyte‐specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosis

1992 • 92 citations

Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders.

1990 • 76 citations

IL4 dictates T-cell differentiation

1993 • 70 citations

Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation.

1993 • 61 citations

Soluble and Cellular Markers of T Cell Activation in Patients with Pulmonary Sarcoidosis

1993 • 59 citations

Detection of a soluble form of the CD30 antigen in sera of patients with lymphoma, adult T‐cell leukemia and infectious mononucleosis

1990 • 53 citations

Interleukin-4 inhibits both paracrine and autocrine tumor necrosis factor-alpha-induced proliferation of B chronic lymphocytic leukemia cells

1992 • 52 citations

Elevated levels of T cell activation antigen CD27 and increased interleukin‐4 production in human lymphatic filariasis

1993 • 47 citations

The 1A4 molecule (CD27) is involved in T cell activation.

1991 • 45 citations

Expression of the T1 (CD5, p67) surface antigen in B‐CLL and B‐NHL and its correlation with other B‐cell differentiation markers

1986 • 23 citations

Serum levels of soluble CD27 in renal transplant recipients.

1992 • 18 citations

New Developments in Flow Cytometric Analyses of Lymphocyte Markers

1992 • 17 citations