The CD27 membrane receptor, a lymphocyte‐specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

1985 • 1,143 citations

Mechanism of antigen-driven selection in germinal centres

1989 • 1,097 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

Why are proteins O-glycosylated?

1990 • 708 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

Leukocyte Typing II

1986 • 688 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

1990 • 614 citations

Glycolipid Anchoring of Plasma Membrane Proteins

1990 • 539 citations

A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

1989 • 527 citations

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1990 • 445 citations

Shedding of tumor necrosis factor receptors by activated human neutrophils.

1990 • 443 citations

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity

1989 • 442 citations

Soluble cytokine receptors are present in normal human urine.

1989 • 441 citations

A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact

1990 • 409 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor.

1990 • 375 citations

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

1990 • 335 citations

A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.

1990 • 292 citations

Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition.

1988 • 274 citations

Inhibition of mucin glycosylation by aryl-N-acetyl-α-galactosaminides in human colon cancer cells

1989 • 260 citations

Isolation and characterization of a tumor necrosis factor binding protein from urine

1989 • 249 citations

The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.

1991 • 245 citations

Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen.

1987 • 231 citations

A new superfamily of cell surface proteins related to the nerve growth factor receptor

1991 • 172 citations

The T cell triggering molecule Tp103 is associated with dipeptidyl aminopeptidase IV activity.

1990 • 171 citations

Rapid modulation of homing receptors (gp90MEL-14) induced by activators of protein kinase C. Receptor shedding due to accelerated proteolytic cleavage at the cell surface.

1990 • 168 citations

Structure-function relationships for the IL 2-receptor system. IV. Analysis of the sequence and ligand-binding properties of soluble Tac protein.

1987 • 165 citations

Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.

1990 • 154 citations

Identification of a truncated form of the nerve growth factor receptor.

1988 • 145 citations

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor.

1990 • 139 citations

CD27 expression by a distinct subpopulation of human B lymphocytes

1990 • 138 citations

Characterization of a tumor necrosis factor alpha (TNF-alpha) inhibitor: evidence of immunological cross-reactivity with the TNF receptor.

1990 • 130 citations

A soluble form of the human T cell differentiation antigen CD27 is released after triggering of the TCR/CD3 complex.

1991 • 125 citations

Elevated levels of a soluble form of the T cell activation antigen CD27 in cerebrospinal fluid of multiple sclerosis patients

1991 • 96 citations

Regulation of expression of CD27, a T cell-specific member of a novel family of membrane receptors.

1991 • 94 citations

Identification, purification, and characterization of truncated forms of the human nerve growth factor receptor

1989 • 63 citations

Nerve growth factor binding domain of the nerve growth factor receptor.

1991 • 59 citations

Serial levels of soluble interleukin 2 receptor in the peripheral blood of patients with rheumatoid arthritis: correlations with disease activity.

1990 • 54 citations

S152 (CD27). A modulating disulfide-linked T cell activation antigen.

1988 • 50 citations

CD27 induction on thymocytes.

1990 • 35 citations

Alternative molecular form of human T cell‐specific antigen CD27 expressed upon T cell activation

1989 • 34 citations

Biological Signal Transduction

1991 • 15 citations

T14, A Non-modulating 150-Kd T Cell Surface Antigen

1986 • 12 citations

A Novel Disulfide-Linked Cell Surface Molecule Present on Resting and Activated Human T Lymphocytes

1986 • 6 citations

The T Cell Activation Molecule CD27 Is a Member of the Nerve Growth Factor Receptor Gene Family

1991 • 5 citations