Induction of matrix metalloproteinase 9 expression in breast carcinoma cells by a soluble factor from fibroblasts

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Growth Factors and Cancer

1991 • 2,044 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.

1993 • 704 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.

1992 • 502 citations

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro.

1989 • 477 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.

1993 • 428 citations

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.

1990 • 398 citations

Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells.

1994 • 395 citations

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

1992 • 331 citations

Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes

1991 • 307 citations

M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.

1993 • 298 citations

v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

1993 • 291 citations

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

1993 • 283 citations

Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.

1993 • 260 citations

Galectin-3 Is a Novel Substrate for Human Matrix Metalloproteinases-2 and -9

1994 • 259 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase

1989 • 233 citations

Metalloproteinases in tumor progression: the contribution of MMP-9.

1994 • 209 citations

Ras oncogene mediated induction of a 92kDa metalloproteinase; strong correlation with the malignant phenotype

1988 • 209 citations

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.

1990 • 202 citations

Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines.

1991 • 194 citations

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia.

1993 • 182 citations

Neutral proteinases of human mononuclear phagocytes. Cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases.

1991 • 179 citations

Enhanced expression of tissue inhibitor of metalloproteinase‐2 (TIMP‐2) in the stroma of breast carcinomas correlates with tumor recurrence

1994 • 173 citations

CYCLIN B EXPRESSION IN HELA CELLS DURING THE G2 BLOCK INDUCED BY IONIZING RADIATION

1991 • 165 citations

Transforming growth factor-beta and interleukin-1 modulate metalloproteinase expression by corneal stromal cells.

1991 • 163 citations

Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas

1992 • 143 citations

Matrix metalloproteinase 9 expression in primary human prostatic adenocarcinoma and benign prostatic hyperplasia

1994 • 130 citations

Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M(r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes.

1993 • 126 citations

Induction and stimulation of 92-kDa gelatinase / type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor α

1990 • 124 citations

Gelatinases of metastatic cell lines of murine colonic carcinoma as detected by substrate-gel electrophoresis

1988 • 117 citations

92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.

1993 • 110 citations

Demonstration of 72-kDa and 92-kDa Forms of Type IV Collagenase in Human Skin: Variable Expression in Various Blistering Diseases, Induction During Re-Epithelialization, and Decrease by Topical Glucocorticoids

1993 • 106 citations

72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.

1994 • 103 citations

Induction of fibroblast 92 kDa gelatinase/type iv collagenase expression by direct contact with metastatic tumor cells

1994 • 84 citations

Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.

1995 • 79 citations

Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor

1993 • 73 citations

Inhibition of Matrix Metalloproteinase 9 Activation by a Specific Monoclonal Antibody

1993 • 70 citations

Expression of 92-kDa Type IV Collagenase mRNA by Eosinophils Associated with Basal Cell Carcinoma

1992 • 67 citations

MMP-9 (gelatinase B) mRNA is expressed during mouse neurogenesis and may be associated with vascularization

1995 • 67 citations

Developmental expression of MMP‐9 (gelatinase B) mRNA in mouse embryos

1995 • 65 citations

Coordinate enhancement of gelatinase a mRNA and activity levels in human fibroblasts in response to breast‐adenocarcinoma cells

1994 • 58 citations

Relationship between the clinical aggressiveness of large cell immunoblastic lymphomas and expression of 92 kDa gelatinase (type IV collagenase) and tissue inhibitor of metalloproteinases-1 (TIMP-1) RNAs.

1992 • 56 citations

Gelatinolytic metalloproteinase secretion patterns in ocular melanoma.

1992 • 45 citations

The effect of E1A transfection on MMP‐9 expression and metastatic potential

1995 • 29 citations

Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.

1993 • 15 citations

Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues

1991 • 14 citations