Gelatinases of metastatic cell lines of murine colonic carcinoma as detected by substrate-gel electrophoresis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.

1975 • 573 citations

Cancer metastasis

1982 • 567 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials.

1987 • 315 citations

Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules.

1980 • 279 citations

An endopeptidase from rheumatoid synovial tissue culture

1972 • 252 citations

Detergent-activation of latent collagenase and resolution of its component molecules

1982 • 202 citations

Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen

1985 • 195 citations

Secretion of basement membrane collagen degrading enzyme and plasminogen activator by transformed cells – role in metastasis

1982 • 195 citations

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans

1978 • 149 citations

Characterization of metastatic clones derived from a metastatic variant of mouse colon adenocarcinoma 26.

1983 • 130 citations

Presence of a gelatin-specific proteinase and its latent form in human leucocytes

1974 • 127 citations

Purification of a Type V Collagen Degrading Metalloproteinase from Rabbit Alveolar Macrophages

1984 • 98 citations

Enrichment of collagen and gelatin degrading activities in the plasma membranes of human cancer cells.

1987 • 60 citations

Human Leucocyte Neutral Proteases, with Special Reference to Collagen Metabolism1

1978 • 55 citations

Metastatic mouse melanoma cells release collagen-gelatin degrading metalloproteinases as components of shed membrane vesicles

1987 • 51 citations

Purification and characterization of a connective-tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells

1987 • 25 citations

Collagen-fibronectin interactions in normal and rous sarcoma virus-transformed avian tendon cells: Possible mechanisms for increased extracellular matrix turnover after transformation

1987 • 4 citations