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Gut hormone PYY3-36 physiologically inhibits food intake

2002 • 2,263 citations

The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans

2002 • 1,331 citations

Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion

2002 • 1,246 citations

The Need to Feed

2002 • 1,089 citations

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

2002 • 1,055 citations

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

2000 • 983 citations

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

2002 • 887 citations

Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol

2002 • 776 citations

Central Administration of Oleic Acid Inhibits Glucose Production and Food Intake

2002 • 640 citations

Elevated plasma ghrelin levels in Prader–Willi syndrome

2002 • 604 citations

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

2002 • 547 citations

Food Fails to Suppress Ghrelin Levels in Obese Humans

2002 • 517 citations

Opioid modulation of taste hedonics within the ventral striatum

2002 • 514 citations

Insulin Regulates Plasma Ghrelin Concentration

2002 • 500 citations

Weight loss increases circulating levels of ghrelin in human obesity

2002 • 498 citations

A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding

2002 • 489 citations

Activation of Central Melanocortin Pathways by Fenfluramine

2002 • 481 citations

Neither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice

2002 • 421 citations

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

2002 • 408 citations

The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins

2002 • 406 citations

Genetic approaches to studying energy balance: perception and integration

2002 • 401 citations

The Neuroanatomical Axis for Control of Energy Balance

2002 • 390 citations

Genetics and Pathophysiology of Human Obesity

2003 • 381 citations

Evidence That the Caudal Brainstem Is a Target for the Inhibitory Effect of Leptin on Food Intake

2002 • 374 citations

Peripheral ghrelin selectively increases Fos expression in neuropeptide Y – synthesizing neurons in mouse hypothalamic arcuate nucleus

2002 • 330 citations

Nicotinic receptor‐mediated effects on appetite and food intake

2002 • 300 citations

The Diverse Roles of Specific GLP-1 Receptors in the Control of Food Intake and the Response to Visceral Illness

2002 • 285 citations

Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice

2002 • 245 citations

Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity

2002 • 221 citations

Insulin, Unlike Food Intake, Does Not Suppress Ghrelin in Human Subjects

2002 • 210 citations

Plasma Ghrelin Concentrations Are Not Regulated by Glucose or Insulin

2003 • 209 citations

Brain Stem Is a Direct Target for Leptin’s Action in the Central Nervous System

2002 • 202 citations

Restricted distribution of galanin receptor 3 (GalR3) mRNA in the adult rat central nervous system

2002 • 196 citations

Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity

2002 • 171 citations

Eating Elicited by Orexin-A, But Not Melanin-Concentrating Hormone, Is Opioid Mediated

2002 • 154 citations

Ghrelin Stimulates GH But Not Food Intake in Arcuate Nucleus Ablated Rats

2002 • 153 citations

A Variation in the Ghrelin Gene Increases Weight and Decreases Insulin Secretion in Tall, Obese Children

2002 • 152 citations

GH-Releasing Peptide-2 Increases Fat Mass in Mice Lacking NPY: Indication for a Crucial Mediating Role of Hypothalamic Agouti-Related Protein

2002 • 151 citations

Diverse functions of neuropeptide Y revealed using genetically modified animals

2002 • 150 citations

Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats

2002 • 147 citations

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake.

2002 • 146 citations

Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype

2002 • 146 citations

Hypothalamic regulation of energy homeostasis

2002 • 135 citations

Insulin and Leptin Combine Additively to Reduce Food Intake and Body Weight in Rats

2002 • 130 citations

Ghrelin Gene: Identification of Missense Variants and a Frameshift Mutation in Extremely Obese Children and Adolescents and Healthy Normal Weight Students

2002 • 123 citations

Melanocortin 4 Receptor Sequence Variations Are Seldom a Cause of Human Obesity: The Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis Cohort

2002 • 123 citations

The Rat Arcuate Nucleus Integrates Peripheral Signals Provided by Leptin, Insulin, and a Ghrelin Mimetic

2002 • 123 citations

Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats and food intake

2002 • 119 citations

Leptin and Neuropeptide Y Have Opposing Modulatory Effects on Nucleus of the Solitary Tract Neurophysiological Responses to Gastric Loads: Implications for the Control of Food Intake

2002 • 118 citations

Effects of ghrelin and amylin on dopamine, norepinephrine and serotonin release in the hypothalamus

2002 • 116 citations

Centrally Administered Galanin‐Like Peptide Modifies Food Intake in the Rat: A Comparison with Galanin

2002 • 105 citations

Evidence for the Existence of Distinct Central Appetite, Energy Expenditure, and Ghrelin Stimulation Pathways as Revealed by Hypothalamic Site-Specific Leptin Gene Therapy

2002 • 104 citations

Dietary Peptides Induce Satiety via Cholecystokinin-A and Peripheral Opioid Receptors in Rats

2002 • 104 citations

Resistance to the Satiety Action of Leptin Following Chronic Central Leptin Infusion is Associated with the Development of Leptin Resistance in Neuropeptide Y Neurones

2002 • 100 citations

Role of Ghrelin in Streptozotocin-Induced Diabetic Hyperphagia

2002 • 93 citations

Comparison of Central and Peripheral Administration of C75 on Food Intake, Body Weight, and Conditioned Taste Aversion

2002 • 92 citations

Chronic Central Melanocortin-4 Receptor Antagonism and Central Neuropeptide-Y Infusion in Rats Produce Increased Adiposity by Divergent Pathways

2002 • 86 citations

A Polymorphism in the Human Agouti-Related Protein Is Associated with Late-Onset Obesity

2002 • 84 citations

Selective Antagonism of the NPY Y5 Receptor Does Not Have a Major Effect on Feeding in Rats

2002 • 74 citations

Disruptions in feeding and body weight control in gastrin-releasing peptide receptor deficient mice

2002 • 69 citations

Long-Term Suppression of Weight Gain, Adiposity, and Serum Insulin by Central Leptin Gene Therapy in Prepubertal Rats: Effects on Serum Ghrelin and Appetite-Regulating Genes

2002 • 64 citations

Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level in rats

2002 • 62 citations

Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods

2002 • 56 citations

Acute 3rd-ventricular amylin infusion potently reduces food intake but does not produce aversive consequences

2002 • 54 citations

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein

2002 • 54 citations

Energy Metabolism and Turnover Are Increased in Mice Lacking the Cholecystokinin-B Receptor

2002 • 47 citations

Sustained orexigenic effect of Agouti related protein may be not mediated by the melanocortin 4 receptor

2002 • 46 citations

Appetite suppression based on selective inhibition of NPY receptors

2002 • 44 citations

Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats

2003 • 44 citations

Fourth ventricular CART reduces food and water intake and produces a conditioned taste aversion in rats.

2002 • 39 citations

Phenotypes of mice with invalidation of cholecystokinin (CCK1 or CCK2) receptors

2002 • 35 citations

Gastrin-releasing peptide microinjected into the amygdala inhibits feeding

2002 • 21 citations

Effects of Gastrin-releasing Peptide1-27 on Taste Responses in the Rat

2002 • 2 citations