The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

Lambdoid phages that simplify the recovery of in vitro recombinants

1977 • 779 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.

1990 • 350 citations

Use of selectively trypsinized nucleosome core particles to analyze the role of the histone “tails” in the stabilization of the nucleosome

1989 • 330 citations

Participation of core histone "tails" in the stabilization of the chromatin solenoid.

1982 • 264 citations

Effects of histone H4 depletion on the cell cycle and transcription of Saccharomyces cerevisiae.

1988 • 225 citations

Dissection of Chromosome Structure with Trypsin and Nucleases

1974 • 201 citations

Use of a chemically modified T7 DNA polymerase for manual and automated sequencing of supercoiled DNA.

1988 • 184 citations

Acetylation of histone H4 and its role in chromatin structure and function

1980 • 183 citations

Foot-and-mouth disease virus protease 3C induces specific proteolytic cleavage of host cell histone H3

1990 • 175 citations

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

1987 • 164 citations

The structure and assembly of active chromatin

1990 • 133 citations

Nucleosome linking number change controlled by acetylation of histones H3 and H4.

1990 • 132 citations

A highly basic histone H4 domain bound to the sharply bent region of nucleosomal DNA

1988 • 123 citations

Folding of DNA by histones which lack their NH2-terminal regions.

1978 • 120 citations

Localization of the sites along nucleosome DNA which interact with NH2-terminal histone regions.

1977 • 119 citations

Histone hyperacetylation can induce unfolding of the nucleosome core particle

1990 • 118 citations

Overlap hybridization screening: Isolation and characterization of overlapping DNA fragments surrounding the leu2 gene on yeast chromosome III

1979 • 113 citations

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

1990 • 108 citations

Yeast histone H2A and H2B amino termini have interchangeable functions

1986 • 88 citations

Yeast H3 and H4 histone messenger RNAs are transcribed from two non-allelic gene sets

1983 • 86 citations

Foot-and-mouth disease virus protease 3C inhibits cellular transcription and mediates cleavage of histone H3

1990 • 80 citations

Chromatin core particle unfolding induced by tryptic cleavage of histones

1977 • 75 citations

Yeast histone H2B containing large amino terminus deletions can function in vivo

1983 • 73 citations

Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.

1990 • 71 citations

Histone H3 and H4 gene deletions in Saccharomyces cerevisiae.

1988 • 52 citations

Fluorescence of yeast vitally stained with ethidium bromide and propidium iodide.

1981 • 32 citations