Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Current protocols in molecular biology

1988 • 7,584 citations

High resolution acrylamide gel electrophoresis of histones

1969 • 2,470 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Sodium butyrate inhibits histone deacetylation in cultured cells

1978 • 1,008 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

A direct link between core histone acetylation and transcriptionally active chromatin.

1988 • 905 citations

Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.

1976 • 523 citations

Chromatin reconstituted from tandemly repeated cloned DNA fragments and core histones: A model system for study of higher order structure

1985 • 469 citations

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

1978 • 459 citations

Histone acetylation reduces nucleosome core particle linking number change

1989 • 394 citations

Initiation of mammalian protein synthesis

1977 • 341 citations

Chapter 16 Resolution of Histonies by Polyacrylamide Gel Electrophoresis in Presence of Nonionic Detergents

1978 • 329 citations

Structural features of a phased nucleosome core particle.

1983 • 323 citations

A low resolution structure for the histone core of the nucleosome

1980 • 309 citations

Structure of chromatin containing extensively acetylated H3 and H4

1978 • 290 citations

Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin

1983 • 231 citations

Homogeneous reconstituted oligonucleosomes, evidence for salt-dependent folding in the absence of histone H1

1989 • 224 citations

An underlying repeat in some transcriptional control sequences corresponding to half a double helical turn of DNA

1986 • 214 citations

Histone hyperacetylation: its effects on nucleosome conformation and stability

1986 • 211 citations

Acetylation of histone H4 and its role in chromatin structure and function

1980 • 183 citations

Partial Purification of the Template-Active Fraction of Chromatin: A Preliminary Report

1974 • 175 citations

Selective release of chromosomal proteins during limited DNAase 1 digestion of avian erythrocyte chromatin

1977 • 166 citations

Affinity chromatographic purification of nucleosomes containing transcriptionally active DNA sequences

1987 • 164 citations

DNA associated with hyperacetylated histone is preferentially digested by DNase I

1978 • 147 citations

Acetylated histone H4 is preferentially associated with template-active chromatin.

1978 • 146 citations

Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites.

1986 • 142 citations

Genes transcribed at diverse rates have a similar conformation in chromatin

1977 • 140 citations

Selective association of the trout-specific H6 protein with chromatin regions susceptible to DNase I and DNase II: possible location of HMG-T in the spacer region between core nucleosomes.

1977 • 138 citations

Sequence-specific positioning of core histones on an 860 base-pair DNA

1987 • 134 citations

Nucleosome linking number change controlled by acetylation of histones H3 and H4.

1990 • 132 citations

Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc.

1987 • 125 citations

An altered subunit configuration associated with the actively transcribed DNA of integrated adenovirus genes

1977 • 124 citations

A highly basic histone H4 domain bound to the sharply bent region of nucleosomal DNA

1988 • 123 citations

Histone hyperacetylation can induce unfolding of the nucleosome core particle

1990 • 118 citations

Separation and analysis of histone subfractions differing in their degree of acetylation: Some correlations with genetic activity in development

1972 • 109 citations

Chicken erythrocyte polynucleosomes which are soluble at physiological ionic strength and contain linker histones are highly enriched hi β-globin gene sequences

1987 • 99 citations

The effect of histone hyperacetylation on the nuclease sensitivity and the solubility of chromatin.

1981 • 97 citations

Nucleosomal Particles Open as the Histone Core Becomes Hyperacetylated

1983 • 93 citations

Effect of Acetylation on the Binding of N-Terminal Peptides of Histone H4 to DNA

1982 • 85 citations

Photofootprint of nucleosome core DNA in intact chromatin having different structural states

1988 • 78 citations

A protein released by DNAase I digestion of drosophila nuclei is preferentially associated with puffs

1978 • 76 citations

Modulation of the Nucleosome Structure by Histone Acetylation

1980 • 76 citations

Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis

1979 • 75 citations

Hyperacetylation of core histones does not cause unfolding of nucleosomes. Neutron scatter data accords with disc shape of the nucleosome.

1986 • 75 citations

Altered nucleosomes of active nucleolar chromatin contain accessible histone H3 in its hyperacetylated forms.

1987 • 60 citations

Thermal Denaturation Studies of Acetylated Nucleosomes and Oligonucleosmes

1982 • 55 citations

DNA sequence-directed nucleosome reconstitution on 5S RNA genes of Xenopus laevis.

1987 • 55 citations

Patterns of histone acetylation in Physarum polycephalum

1984 • 55 citations

Selective displacement of histone H1 from whole HeLa nuclei: effect on chromatin structure in situ as probed by micrococcal nuclease

1979 • 51 citations

Structure of the Nucleosome Core Particle at 8 Å Resolution

1989 • 51 citations

Cell cycle-dependent changes in conformation and composition of nucleosomes containing human histone gene sequences

1987 • 41 citations

N-Butyrate incubation of immature chicken erythrocytes preferentially enhances the solubility of β^ chromatin

1985 • 40 citations

Dynamics of Nucleosome Structure Studied by Fluorescence

1978 • 39 citations

Acetylation and phosphorylation of Drosophila histones

1977 • 39 citations

Analysis of the Binding of High Mobility Group Protein 17 to the Nucleosome Core Particle by 1H NMR Spectroscopy

1989 • 29 citations

A correlation between nucleosome spacer region susceptibility to DNase 1 and histone acetylation

1979 • 29 citations

Histone acetylation in replication and transcription: Turnover at specific acetylation sites in histone H4 from Physarum polycephalum

1986 • 28 citations

Preparation of histone variants and high-mobility group proteins by reversed-phase high-performance liquid chromatography

1984 • 27 citations

Rapid separation of histones by high-performance liquid chromatography on C4 reversed-phase columns

1986 • 25 citations

The β-globin domain in immature chicken erythrocytes: enhanced solubility is coincident with histone hyperacetylation

1986 • 25 citations

Fractionation of Calf Thymus Histone by a New Method of CM-cellulose Chromatography*

1970 • 22 citations

The identity of conformational states of reconstituted and native histone octamers

1983 • 20 citations

Precise nucleosome positioning in the promoter of the chickenβ^Aglobin gene

1988 • 18 citations

Histone Organization in Chromatin: Comparisons of Nucleosomes and Subnucleosomal Particles from Erythrocyte, Myeloma, and Yeast Chromatin

1978 • 15 citations

Reversibility of nucleosome conformation perturbed by urea

1978 • 13 citations

Carboxyxmethylcellulose Chromatography in 6M Urea and Zone Electrophoresis of Calf Thymus Histone*

1970 • 10 citations

Dependence of the linking deficiency of supercolled minichromosomes upon nucleosome distortion

1989 • 7 citations