Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay

1988 • 773 citations

Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase

1996 • 566 citations

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

1999 • 554 citations

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

1996 • 521 citations

Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke

1998 • 414 citations

The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39.

1997 • 411 citations

Primary Prevention of Stroke

1995 • 367 citations

Purification and Cloning of a Soluble ATP-Diphosphohydrolase (Apyrase) from Potato Tubers (Solanum tuberosum)

1996 • 319 citations

Neuronal Protection in Stroke by an sLe ^x -Glycosylated Complement Inhibitory Protein

1999 • 313 citations

CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase

1996 • 290 citations

Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke

1997 • 285 citations

Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis

1993 • 279 citations

Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene

1990 • 268 citations

The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.

1994 • 256 citations

Strain-Related Differences in Susceptibility to Transient Forebrain Ischemia in SV-129 and C57Black/6 Mice

1997 • 249 citations

Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregation.

1998 • 237 citations

Procedural and Strain-related Variables Significantly Affect Outcome in a Murine Model of Focal Cerebral Ischemia

1996 • 220 citations

Exacerbation of Cerebral Injury in Mice That Express the P-Selectin Gene

1997 • 198 citations

Use of a Spectrophotometric Hemoglobin Assay to Objectively Quantify Intracerebral Hemorrhage in Mice

1997 • 196 citations

Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition.

1998 • 194 citations

Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

1998 • 189 citations

Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase. Thromboregulation by endothelial cells.

1991 • 180 citations

Monocytes and tissue factor promote thrombosis in a murine model of oxygen deprivation.

1997 • 154 citations

Spontaneous thrombosis in mice carrying the factor V Leiden mutation

2000 • 133 citations

Effects of acetylsalicylic acid in stroke patients evidence of nonresponders in a subpopulation of treated patients

1991 • 125 citations

Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: blockade of aggregation and secretion by an aspirin-insensitive mechanism

1991 • 99 citations

cAMP-Mediated Vascular Protection in an Orthotopic Rat Lung Transplant Model

1996 • 65 citations

Targeted Inhibition of Intrinsic Coagulation Limits Cerebral Injury in Stroke without Increasing Intracerebral Hemorrhage

1999 • 64 citations

Enhanced Preservation of Orthotopically Transplanted Rat Lungs by Nitroglycerin but Not Hydralazine

1995 • 61 citations

Analyses of thrombocytopenia in idiopathic thrombocytopenic purpura- prone mice by platelet transfer experiments between (NZW x BXSB)F1 and normal mice

1990 • 42 citations

Determination by microcoulometric gas chromatography of chlorpromazine metabolites in human urine

1965 • 24 citations

The Results of CAPRIE, IST and CAST

1998 • 22 citations

Clinical considerations in selecting antiplatelet therapy in cerebrovascular disease

1998 • 10 citations

Gene structure and chromosome location of mouse <i>Cd39</i> coding for an ecto-apyrase

1998 • 7 citations