Cyclosporin

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Rheumatoid Arthritis

1990 • 1,565 citations

Biological effects of cyclosporin A: A new antilymphocytic agent

1976 • 1,501 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Cyclosporine

1989 • 1,340 citations

REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY

1984 • 1,284 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

1992 • 811 citations

Effects of the new anti-lymphocytic peptide cyclosporin A in animals.

1977 • 710 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981 • 632 citations

Effects of Cyclosporine Immunosuppression in Insulin-Dependent Diabetes Mellitus of Recent Onset

1984 • 555 citations

Cyclosporine Improves Psoriasis in a Double-blind Study

1986 • 535 citations

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes

1989 • 513 citations

DOUBLE-MASKED TRIAL OF CYCLOSPORIN VERSUS COLCHICINE AND LONG-TERM OPEN STUDY OF CYCLOSPORIN IN BEHÇET'S DISEASE

1989 • 478 citations

CYCLOSPORIN INCREASES THE RATE AND LENGTH OF REMISSIONS IN INSULIN-DEPENDENT DIABETES OF RECENT ONSET

1986 • 443 citations

Cyclosporine for Plaque-Type Psoriasis

1991 • 427 citations

First-pass metabolism of cyclosporin by the gut

1991 • 425 citations

Treatment of Aplastic Anemia with Antilymphocyte Globulin and Methylprednisolone with or without Cyclosporine

1991 • 425 citations

Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis

1991 • 419 citations

Risk Factors for Cyclosporine-Induced Nephropathy in Patients with Autoimmune Diseases

1992 • 409 citations

A Placebo-Controlled, Double-Blind, Randomized Trial of Cyclosporine Therapy in Active Chronic Crohn's Disease

1989 • 380 citations

Preliminary Results of a Double-Blind, Randomized, Placebo-Controlled Trial of Cyclosporine in Myasthenia Gravis

1987 • 375 citations

Effects of Cyclosporine A on T Cell Development and Clonal Deletion

1988 • 354 citations

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1990 • 353 citations

Renal Histopathologic Alterations in Patients Treated with Cyclosporine for Uveitis

1986 • 350 citations

Prednisone and Cyclosporine in the Treatment of Severe Graves' Ophthalmopathy

1989 • 347 citations

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.

1985 • 343 citations

Cyclosporin Clinical Pharmacokinetics

1993 • 338 citations

Trial of cyclosporin in corticosteroid-dependent chronic severe asthma

1992 • 334 citations

Factors Associated with Early Remission of Type I Diabetes in Children Treated with Cyclosporine

1988 • 330 citations

Preliminary report: cyclosporin in treatment of severe active ulcerative colitis

1990 • 321 citations

Modulation of multidrug-resistant multiple myeloma by cyclosporin

1992 • 317 citations

Isolation and amino acid sequence of cyclophilin.

1986 • 294 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Recurrent focal glomerulosclerosis: Natural history and response to therapy

1992 • 270 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T Lymphocyte

1986 • 247 citations

The pathophysiology of psoriasis

1991 • 239 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR.

1980 • 239 citations

Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis

1990 • 236 citations

Clearance of psoriasis with low dose cyclosporin.

1986 • 233 citations

Rusting of the Lock and Key Model for Protein-Ligand Binding

1991 • 223 citations

A Randomized Controlled Trial of Prednisone in Patients with Idiopathic Membranous Nephropathy

1989 • 219 citations

Calcium channel blockers protect transplant patients from cyclosporine-induced daily renal hypoperfusion

1993 • 217 citations

Effect of recombinant IL 2 and gamma-IFN on proliferation and differentiation of human B cells.

1985 • 216 citations

Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

1986 • 214 citations

Efficacy and toxicity of cyclosporine in chronic progressive multiple sclerosis: A randomized, double‐blinded, placebo‐controlled clinical trial

1990 • 214 citations

A Controlled Trial of Cyclosporine in the Treatment of Primary Biliary Cirrhosis

1990 • 212 citations

Low dose cyclosporin A versus pulsed cyclophosphamide in Behcet's syndrome: a single masked trial.

1992 • 206 citations

Cyclosporins as drug resistance modifiers

1992 • 205 citations

Effect of Topical Cyclosporine Rinse on Oral Lichen Planus

1990 • 202 citations

Ciclosporin and prednisone v. prednisone in treatment of Graves' ophthalmopathy: a controlled, randomized and prospective study

1986 • 189 citations

Spontaneous Canine Keratoconjunctivitis Sicca

1989 • 187 citations

Low-dose cyclosporin A in severe psoriasis. A double-blind study

1988 • 187 citations

CYCLOSPORIN PREVENTS DIABETES IN BB WISTAR RATS

1983 • 183 citations

Oral cyclosporine for the treatment of alopecia areata

1990 • 183 citations

Glucocorticoid Resistance in Chronic Asthma: Peripheral Blood T Lymphocyte Activation and Comparison of the T Lymphocyte Inhibitory Effects of Glucocorticoids and Cyclosporin A

1991 • 179 citations

METABOLIC AND IMMUNOLOGICAL EFFECTS OF CYCLOSPORIN IN RECENTLY DIAGNOSED TYPE 1 DIABETES MELLITUS

1985 • 177 citations

Cyclosporine Eyedrops for the Treatment of Severe Vernal Keratoconjunctivitis

1986 • 175 citations

Oral cyclosporine in the treatment of inflammatory and noninflammatory dermatoses. A clinical and immunopathologic analysis.

1990 • 174 citations

Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo.

1990 • 174 citations

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression.

1986 • 171 citations

Cyclosporin a. Inhibition of experimental autoimmune uveitis in Lewis rats.

1981 • 171 citations

Limited Duration of Remission of Insulin Dependency in Children With Recent Overt Type I Diabetes Treated With Low-Dose Cyclosporin

1990 • 168 citations

Topical Use of Cyclosporine in the Treatment of Vernal Keratoconjunctivitis

1990 • 168 citations

Cyclosporine A induced remission of relapsing nephrotic syndrome in children

1988 • 168 citations

The Presence of Cyclosporine in Body Tissues and Fluids During Pregnancy

1985 • 165 citations

Antipruritic effect of oral cyclosporin A in atopic dermatitis.

1990 • 164 citations

Randomized, Double-Masked Study of Cyclosporine Compared to Prednisolone in the Treatment of Endogenous Uveitis

1991 • 162 citations

Topical Cyclosporine in Vernal Keratoconjunctivitis

1991 • 157 citations

Cyclosporin a treatment in primary biliary cirrhosis: Results of a long-term placebo controlled trial

1993 • 157 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. III. CsA inhibits the production of T lymphocyte growth factors in secondary mixed lymphocyte responses but does not inhibit the response of primed lymphocytes to TCGF.

1982 • 155 citations

Disposition of cyclosporine in several animal species and man. I. Structural elucidation of its metabolites.

1984 • 155 citations

CYCLOSPORIN IN JUVENILE DERMATOMYOSITIS

1989 • 155 citations

Preventive effects of Cyclosporin on diabetes in NOD mice

1986 • 155 citations

Pharmacokinetic Drug Interactions with Cyclosporin (Part I)1

1990 • 154 citations

Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.

1989 • 152 citations

Factors Influencing the Pharmacokinetics of Cyclosporine in Man

1991 • 152 citations

Anti-Inflammatory Effect of Cyclosporin A on Human Skin Mast Cells

1992 • 149 citations

Consensus document: Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine.

1990 • 149 citations

The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis

1987 • 147 citations

The pathomechanisms of psoriasis; the skin immune system and cyclosporin

1988 • 146 citations

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA

1990 • 143 citations

Stimulation of immunoglobulin secretion in human B lymphocytes as a direct effect of high concentrations of IL 2.

1984 • 143 citations

Cyclosporin A Treatment of Refractory Rheumatoid Arthritis

1987 • 142 citations

Distribution of the cyclosporine binding protein cyclophilin in human tissues.

1991 • 142 citations

Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.

1985 • 141 citations

In vivo beneficial effects of cyclosporin A and 1,25-dihydroxyvitamin D3 on the induction of experimental autoimmune thyroiditis

1990 • 139 citations

T lymphocyte participation in antibody-induced experimental glomerulonephritis

1985 • 138 citations

Treatment of Pyoderma Gangrenosum With Cyclosporine

1992 • 136 citations

Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I.

1983 • 136 citations

The absorption site of cyclosporin in the human gastrointestinal tract.

1992 • 135 citations

Cyclosporin in rheumatoid arthritis: a double blind, placebo controlled study in 52 patients.

1988 • 134 citations

Effect of Dexamethasone and Cyclosporin A on Allergen-induced Airway Hyperresponsiveness and Inflammatory Cell Responses in Sensitized Brown-Norway Rats

1992 • 134 citations

Cyclosporine in systemic sclerosis. results of a forty‐eight–week open safety study in ten patients

1993 • 134 citations

Cyclosporine A enhances platelet aggregation

1987 • 133 citations

Triple Agent Immunosuppression in Serpiginous Choroiditis

1991 • 132 citations

Cyclosporin-induced remission of IDDM after early intervention. Association of 1 yr of cyclosporin treatment with enhanced insulin secretion. The Canadian-European Randomized Control Trial Group

1988 • 132 citations

Evaluation of conventional therapy versus cyclosporine A in Behçet's syndrome.

1988 • 130 citations

Short-term use of cyclosporin A in severe psoriasis

1986 • 127 citations

Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines.

1992 • 126 citations

Paradoxical effects of cyclosporin A on collagen arthritis in rats.

1983 • 126 citations

A New Perspective on Canine Keratoconjunctivitis Sicca

1990 • 126 citations

Effect of cyclosporin A on T cell function in vitro: the mechanism of suppression of T cell proliferation depends on the nature of the T cell stimulus as well as the differentiation state of the responding T cell.

1982 • 123 citations

Cyclosporin A in Severe, Treatment-Refractory Rheumatoid Arthritis

1988 • 121 citations

SPARING OF SUPPRESSOR CELLS

1984 • 118 citations

Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.

1983 • 118 citations

Effects of cyclosporin A on the development of immune-mediated interstitial nephritis

1988 • 116 citations

The cyclosporins inhibit lymphocyte activation at more than one site.

1987 • 115 citations

Cyclosporin treatment for rheumatoid arthritis: a placebo controlled, double blind, multicentre study.

1986 • 114 citations

CS-A therapy in MRL-lpr/lpr mice: amelioration of immunopathology despite autoantibody production.

1987 • 113 citations

Treatment of severe lichen planus with cyclosporine

1990 • 112 citations

Therapy with cyclosporine in experimental murine myocarditis with encephalomyocarditis virus.

1986 • 107 citations

Cyclosporine versus azathioprine in the long‐term treatment of multiple sclerosis—results of the german multicenter study

1988 • 106 citations

Cyclosporine treatment of autoimmune chronic active hepatitis

1987 • 106 citations

Studies of the Effect of Cyclosporine in Psoriasis In Vivo: Combined Effects on Activated T Lymphocytes and Epidermal Regenerative Maturation

1992 • 105 citations

CYCLOSPORINE SUPPRESSION OF ENDOTHELIAL PROSTACYCLIN GENERATION

1988 • 105 citations

CYCLOSPORINE AND ITS METABOLITES IN MOTHER AND BABY

1988 • 104 citations

Canadian Consensus Meeting on cyclosporine monitoring: report of the consensus panel

1990 • 104 citations

Small-Bowel Length and the Dose of Cyclosporine in Children after Liver Transplantation

1990 • 103 citations

Immunohistologic Findings and Results of Treatment with Cyclosporine in Ligneous Conjunctivitis

1989 • 102 citations

Clearing of epidermolysis bullosa acquisita with cyclosporine

1988 • 102 citations

Interleukin 2 upregulates expression of its receptor on a T cell clone.

1985 • 102 citations

Oral cyclosporine for severe chronic idiopathic urticaria and angioedema

1991 • 99 citations

The Treatment of Neurosarcoidosis With Cyclosporine

1992 • 99 citations

Intralesional cyclosporine in the treatment of psoriasis

1990 • 99 citations

Multicenter randomized study comparing cyclosporine-A alone and antithymocyte globulin with prednisone for treatment of severe aplastic anemia

1992 • 98 citations

Update on topical cyclosporin A. Background, immunology, and pharmacology.

1990 • 97 citations

Comparison of cyclosporin and chlorambucil in the treatment of steroid-dependent idiopathic nephrotic syndrome: a multicentre randomized controlled trial

1992 • 97 citations

Cyclosporine in psoriasis: A multicenter dose-finding study in severe plaque psoriasis

1992 • 96 citations

USE OF CYCLOSPORIN IN PSORIASIS

1989 • 96 citations

Low-dose cyclosporin A induces relapsing remitting experimental allergic encephalomyelitis in the Lewis rat

1988 • 95 citations

Modulation of Experimental Autoimmune Uveitis With Cyclosporin A

1982 • 95 citations

The treatment of minimal change nephrotic syndrome: Lessons learned from multicentre co-operative studies

1991 • 93 citations

Treatment of nine cases of pemphigus vulgaris with cyclosporine

1988 • 93 citations

Long-term cyclosporin for psoriasis

2006 • 92 citations

Intravenous cyclosporine kinetics in renal failure

1983 • 91 citations

Treatment of idiopathic nephrotic syndrome with cyclosporin A in children.

1991 • 91 citations

Uveitis: pathogenesis

1991 • 91 citations

A Double-blind Study of the Effectiveness of Cyclosporine in Amyotrophic Lateral Sclerosis

1988 • 91 citations

Differential effect of cyclosporin A on the expression of T and B lymphocyte activation antigens.

1984 • 91 citations

An Open, Controlled, Randomized Comparison of Cyclosporine and Azathioprine in the Treatment of Rheumatoid Arthritis: A Preliminary Report

1987 • 91 citations

Receptor-Induced Conformation Change of the Immunosuppressant Cyclosporin A

1991 • 91 citations

Final Report on a Placebo-Controlled, Double-Blind, Randomized, Multicentre Trial of Cyclosporin Treatment in Active Chronic Crohn's Disease

1991 • 89 citations

Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia

1989 • 89 citations

Biotransformation and distribution in blood of cyclosporine and its metabolites.

1986 • 89 citations

Inhibition by cyclosporin A of streptococcal cell wall‐induced arthritis and hepatic granulomas in rats

1986 • 88 citations

The pathophysiology of sandimmune (cyclosporine) in man and animals

1990 • 87 citations

The effects of cyclosporine on acute murine Coxsackie B3 myocarditis.

1986 • 87 citations

Ocular penetration of cyclosporin A. III: The human eye.

1990 • 87 citations

Generalized pustular psoriasis (von Zumbusch) responding to cyclosporin A

1987 • 86 citations

Remission of idiopathic nephrotic syndrome after treatment with cyclosporin A.

1986 • 86 citations

Randomised double blind controlled trial of cyclosporin in multiple sclerosis.

1989 • 86 citations

Cyclosporine treatment of steroid resistant interstitial pneumonitis associated with dermatomyositis/polymyositis.

1987 • 86 citations

Cyclosporin A augments angiotensin II-stimulated rise in intracellular free calcium in vascular smooth muscle cells

1987 • 85 citations

Lymphokine gene expression in vivo is inhibited by cyclosporin A.

1990 • 85 citations

Pathophysiology of cyclosporin A nephrotoxicity: experimental and clinical observations

1992 • 84 citations

Practical Treatment Recommendations for Pharmacotherapy of Behcetʼs Syndrome

1991 • 83 citations

Cyclosporin a Retention Enemas in Refractory Distal Ulcerative Colitis and ‘Pouchitis’

1993 • 83 citations

Efficacy of low-dose cyclosporin A in psoriasis: results of dose-finding studies

1990 • 83 citations

Cyclosporine therapy for advanced Langerhans cell histiocytosis [see comments]

1991 • 83 citations

Enhancement of the oral absorption of cyclosporin in man.

1992 • 82 citations

Mechanisms of action of cyclosporine and effects on connective tissues

1992 • 82 citations

Treatment of pyoderma gangrenosum with cyclosporine: Results in seven patients

1991 • 82 citations

Ciclosporin in the Treatment of Lupus Nephritis

1989 • 82 citations

Cyclosporin A (CyA) in primary Sjogren's syndrome: a double blind study.

1986 • 82 citations

Renal Function and Blood Pressure in Patients Receiving Long-Term, Low-Dose Cyclosporine Therapy for Idiopathic Autoimmune Uveitis

1992 • 80 citations

Effects of cyclosporine and other immunosuppressive drugs on experimental autoimmune uveoretinitis in rats.

1985 • 80 citations

Cyclosporin A in atopic dermatitis: therapeutic resonse is disociated form effects on allergic reactons

1991 • 79 citations

Cyclosporin A in the treatment of chronic demyelinating polyradiculoneuropathy.

1990 • 79 citations

Selective effects of cyclosporin A on colony-forming lymphoid and myeloid cells in man

1979 • 78 citations

Cyclosporin in the treatment of severe chronic idiopathic uveitis.

1990 • 78 citations

Successful treatment of autoimmune enteropathy with cyclosporine

1990 • 78 citations

Cyclosporine in atopic dermatitis

1992 • 78 citations

THE RECURRENCE OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS IN KIDNEY TRANSPLANT PATIENTS TREATED WITH CYCLOSPORINE

1990 • 78 citations

Interferon-gamma gene expression in unstimulated bone marrow mononuclear cells predicts a good response to cyclosporine therapy in aplastic anemia

1992 • 77 citations

Treatment of Lichen Planus

1993 • 77 citations

The Medical Research Council trial of short-term high-dose alternate day prednisolone in idiopathic membranous nephropathy with nephrotic syndrome in adults. The MRC Glomerulonephritis Working Party.

1990 • 77 citations

Nucleotide sequences of fic and fic-1 genes involved in cell filamentation induced by cyclic AMP in Escherichia coli

1989 • 76 citations

Paracentral Rheumatoid Corneal Ulceration

1992 • 76 citations

Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A.

1984 • 76 citations

Infection and Cyclosporine

1989 • 75 citations

Cyclosporine A reduces cerebral vasospasm after subarachnoid hemorrhage in dogs.

1990 • 75 citations

Interaction of cyclosporine A and nonsteroidal anti-inflammatory drugs on renal function in patients with rheumatoid arthritis

1992 • 74 citations

Cyclosporin a in rheumatoid arthritis: preliminary clinical results of an open trial

1987 • 74 citations

Alteration of interleukin-1 production and the acute phase response following medication of adjuvant arthritic rats with cyclosporin-A or methotrexate

1988 • 74 citations

Cyclosporin, a new treatment for autoimmune chronic active hepatitis

1985 • 73 citations

Lack of efficacy of topical cyclosporin A in atopic dermatitis and allergic contact dermatitis.

1991 • 73 citations

Pharmacology of cyclosporine (sandimmune). V. Pharmacological effects on immune function: in vitro studies.

1990 • 73 citations

Renal side-effects of cyclosporin A

1990 • 73 citations

Cyclosporin as a treatment for interstitial lung disease of unknown aetiology.

1991 • 73 citations

Thymus-dependent and -independent regulation of Ia antigen expression in situ by cells in the synovium of rats with streptococcal cell wall-induced arthritis. Differences in site and intensity of expression in euthymic, athymic, and cyclosporin A-treated LEW and F344 rats.

1987 • 72 citations

Cyclosporine A enhances vasopressin-induced Ca2+ mobilization and contraction in mesangial cells

1988 • 72 citations

Cyclosporine increases muscular force generation in Duhenne muscular dystrophy

1993 • 71 citations

Inhibition of Histamine and Prostaglandin D<sub>2</sub> Release from Human Lung Mast Cells by Ciclosporin A

1989 • 71 citations

Toxic epidermal necrolysis treated with cyclosporin

1992 • 70 citations

CYCLOSPORIN A IN THE TREATMENT OF SEVERE BEHÇET’S UVEITIS

1987 • 70 citations

Topical cyclosporine for oral mucosal disorders

1990 • 69 citations

Immunosuppression by cyclosporin a of experimental allergic encephalomyelitis

1982 • 69 citations

Biliary Excretion of Cyclosporine in Liver Transplant Patients.

1985 • 69 citations

Management of patients and side effects during cyclosporine therapy for cutaneous disorders

1990 • 69 citations

Local Cyclosporine Therapy for Experimental Autoimmune Uveitis in Rats

1985 • 69 citations

The progression of the inflammation in established collagen‐induced arthritis can be altered by treatments with immunological or pharmacological agents which inhibit T cell activities

1988 • 68 citations

Cyclosporin A Suppresses ICAM-1 Expression by Papillary Endothelium in Healing Psoriatic Plaques

1991 • 68 citations

High-fat meals increase the clearance of cyclosporine.

1990 • 68 citations

Ulcerative colitis disease activity following treatment of associated primary sclerosing cholangitis with cyclosporin.

1993 • 67 citations

The pathophysiology of Sandimmune (cyclosporine) in man and animals

1990 • 67 citations

Isolation and initial characterization of multiple species of T-lymphocyte subset cDNA clones.

1987 • 67 citations

Topical Cyclosporine in Alopecia Areata

1987 • 66 citations

Suppressive effects of cyclosporin A on the induction of alloreactivity in vitro and in vivo.

1981 • 66 citations

Renal function and biopsy findings after 5 years' treatment with low-dose cyclosporin for psoriasis

1993 • 66 citations

Sympathetic ophthalmia: Visual results with modern immunosuppressive therapy

1992 • 65 citations

Pharmacology and pharmacokinetics of cyclosporine

1991 • 65 citations

Response to autoimmune enteropathy to cyclosporin A therapy.

1991 • 65 citations

Abuse of Cyclopentolate Hydrochloride (Cyclogyl) Drops

1992 • 64 citations

Follow-up of cyclosporin A treatment in Type 1 (insulin-dependent) diabetes mellitus: lack of long-term effects

1991 • 64 citations

HIGH-DOSE CYCLOSPORINE THERAPY IN RECURRENT NEPHROTIC SYNDROME FOLLOWING RENAL TRANSPLANTATION

1990 • 63 citations

Cyclosporin for steroid‐dependent asthma

1991 • 62 citations

Long-Term Cyclosporin A Therapy for Severe Idiopathic Membranous Nephropathy

1993 • 62 citations

The effects of cyclosporin A on non-T cell components of the immune system

1992 • 62 citations

Cyclosporine therapy for pyoderma gangrenosum associated with sclerosing cholangitis and ulcerative colitis

1988 • 61 citations

The paradox of effective therapies but poor long-term outcomes in rheumatoid arthritis

1992 • 61 citations

Successful Treatment of Amegakaryocytic Thrombocytopenic Purpura with Cyclosporine

1985 • 60 citations

Cyclosporine treatment of severe ulcerative colitis in children

1991 • 60 citations

Pharmacology of cyclosporine. VI. Cellular activation: regulation of intracellular events by cyclosporine.

1990 • 60 citations

Cyclosporine: Structure, Pharmacokinetics, and Therapeutic Drug Monitoring

1987 • 59 citations

Mechanisms of Cyclosporine A Inhibition of Antigen-Presenting Activity in Uninvolved and Lesional Psoriatic Epidermis

1990 • 59 citations

Treatment of Idiopathic Membranous Nephropathy Unresponsive to Methylprednisolone and Chlorambucil with Cyclosporin

1987 • 59 citations

Combination low dose Cyclosporin a and steroid therapy in chronic intraocular inflammation

1990 • 59 citations

Pure red cell aplasia: Review of treatment and proposal for a treatment strategy

1990 • 59 citations

Cyclosporin a inhibits the proliferative response and the generation of helper, suppressor and cytotoxic T-cell functions in the autologous mixed lymphocyte reaction

1981 • 58 citations

Long-Term Cyclosporine A Treatment of Steroid-Resistant and Steroid-Dependent Nephrotic Syndrome

1991 • 58 citations

Effects of cyclosporin A on glomerular barrier function in the nephrotic syndrome

1992 • 58 citations

Regression of bone and cartilage loss in adjuvant arthritic rats after treatment with cyclosporin a

1990 • 58 citations

Pilot study of cyclosporin A in patients with symptomatic primary biliary cirrhosis

1988 • 57 citations

The development of B-cell lymphoma in a patient with psoriasis treated with cyclosporine

1992 • 57 citations

HAEMOPHAGOCYTIC SYNDROME TREATED WITH CYCLOSPORIN A: A T CELL DISORDER?

1989 • 57 citations

Practical aspects in the use of cyclosporin in paediatric nephrology

1991 • 57 citations

Treatment of experimental myasthenia gravis with cyclosporin A

1985 • 57 citations

Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A

1989 • 57 citations

Effect of cyclosporin A on spontaneous autoimmune thyroiditis of Obese strain (OS) chickens

1982 • 56 citations

Single and combined effects of the vitamin D analogue KH1060 and cyclosporin A on mercuric-chloride-induced autoimmune disease in the BN rat

1992 • 56 citations

Cyclosporine in the treatment of birdshot retinochoroidopathy.

1988 • 56 citations

Severe hypercholesterolemia inhibits cyclosporin A efficacy in a dose-dependent manner in children with nephrotic syndrome.

1992 • 55 citations

Cyclosporin a treatment of Behçet's disease: a long-term study

1990 • 55 citations

Suppression of experimental allergic neuritis by cyclosporin-A

1983 • 55 citations

Comparison of cyclosporine and D-penicillamine for rheumatoid arthritis: a randomized, double blind, multicenter study.

1991 • 54 citations

Pathogenetic difference between collagen arthritis and adjuvant arthritis.

1984 • 54 citations

Cyclosporin A in combination with photochemotherapy (PUVA) in the treatment of psoriasis

1990 • 54 citations

Effect of Cyclosporine a on the Hearing Loss in Behçet's Disease

1991 • 54 citations

The clinical significance of cyclosporine metabolites

1991 • 54 citations

CYCLOSPORINE—RELATIONSHIP OF SIDE EFFECTS TO MODE OF ACTION

1988 • 53 citations

Relapse rates in moderately severe chronic psoriasis treated with cyclosporin A

1989 • 53 citations

Management of Drug Interactions With Cyclosporine

1991 • 53 citations

Plasma C-Peptide Levels and Clinical Remissions in Recent-Onset Type I Diabetic Patients Treated With Cyclosporin A and Insulin

1990 • 53 citations

Cyclosporin A in nephrotic syndrome of childhood--a 14 month experience.

1986 • 51 citations

Cyclosporine in rheumatoid arthritis

1992 • 51 citations

Adhesion molecule expression in psoriatic skin lesions and the influence of cyclosporin A

1991 • 51 citations

Treatment of adult idiopathic nephrotic syndrome with cyclosporin A: minimal-change disease and focal-segmental glomerulosclerosis. Collaborative Group of the French Society of Nephrology.

1991 • 51 citations

A Randomized Controlled Trial of Low-Dose Prednisone and Ciclosporin versus High-Dose Prednisone in Nephrotic Syndrome of Children

1991 • 51 citations

Elevation of fasting serum lipids in patients treated with low-dose cyclosporine for severe plaque-type psoriasis

1992 • 50 citations

ANALYSIS OF CLONED T CELL FUNCTION

1983 • 50 citations

Cyclosporine therapy in inflammatory bowel disease: open-label experience.

1990 • 50 citations

Immunosuppressive activity of cyclosporine metabolites compared and characterized by mass spectroscopy and nuclear magnetic resonance.

1990 • 50 citations

Combined steroid-cyclosporin treatment of chronic autoimmune diseases

1987 • 50 citations

Short-Term Responsiveness of Membranous Glomerulopathy to Cyclosporine

1992 • 50 citations

Morphologic renal changes during cyclosporine treatment of psoriasis

1992 • 50 citations

Can cyclosporin A induce permanent remission of atopic dermatitis?

1993 • 49 citations

Oral cyclosporin‐A is effective treatment for untreated and also for previously immunosuppressed patients with severe bone marrow failure*

1989 • 49 citations

Long-Term Treatment of Crohnʼs Disease with Cyclosporine

1991 • 49 citations

Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia with cyclosporin A

1992 • 49 citations

Pneumocystis cariniiPneumonia during Cyclosporine Therapy for Ulcerative Colitis

1992 • 48 citations

Cyclosporin in the management of polymyositis and dermatomyositis.

1991 • 48 citations

Therapy for human autoimmune uveitis with low-dose cyclosporine plus bromocriptine.

1988 • 48 citations

Concentrations of Cyclosporin A and Its Metabolites in Human Tissues Postmortem

1991 • 48 citations

Short term cyclosporin A treatment of Behcet's disease.

1987 • 47 citations

The effects of prophylactic cyclosporin A on experimental allergic neuritis (EAN) in the Lewis rat. Induction of relapsing EAN using low dose cyclosporin A

1990 • 47 citations

Cyclosporine-A in the treatment of serpiginous choroiditis

1990 • 47 citations

EFFECT OF INTERLEUKIN 2 ON THE IMMUNOSUPPRESSIVE ACTION OF CYCLOSPORINE

1985 • 47 citations

Cyclosporin A treatment of systemic sclerosis

1990 • 47 citations

Interleukin-6 serum levels correlate with footpad swelling in adjuvant-induced arthritic lewis rats treated with cyclosporin A or indomethacin

1990 • 46 citations

Cyclosporine A for the treatment of necrotizing scleritis and corneal melting in patients with rheumatoid arthritis.

1992 • 46 citations

Ciclosporin A in Acrodermatitis continua

1987 • 46 citations

The Pharmacokinetics and Colonic Tissue Concentrations of Cyclosporine After IV, Oral, and Enema Administration

1991 • 46 citations

Longterm cyclosporine therapy in rheumatoid arthritis.

1991 • 46 citations

Does fish oil protect renal function in cyclosporin‐treated psoriasis patients?

1989 • 46 citations

Ciclosporin treatment in children with steroid-dependent nephrotic syndrome

1990 • 46 citations

The influence of cyclosporin A on the development of actively induced and passively transferred experimental allergic encephalomyelitis

1983 • 46 citations

Effect of Supernatants Derived from T Lymphocyte Culture in Minimal Change Nephrotic Syndrome on Rat Kidney Capillaries

1989 • 46 citations

Studies of Vascular Permeability Factor derived from T Lymphocytes and Inhibitory Effect of Plasma on Its Production in Minimal Change Nephrotic Syndrome

1985 • 46 citations

Cyclosporine in psoriasis treatment. Inhibition of keratinocyte cell-cycle progression in G1 independent of effects on transforming growth factor alpha/epidermal growth factor receptor pathways

1991 • 45 citations

Coxsackievirus B3-induced myocarditis. Autoimmunity is L3T4+ T helper cell and IL-2 independent in BALB/c mice.

1987 • 45 citations

The optimal use of cyclosporin A in autoimmune diseases

1992 • 45 citations

Treatment of severe vernal keratoconjunctivitis with cyclosporine A eyedrops.

1988 • 45 citations

Effects of cyclosporin on collagen induced arthritis in mice.

1986 • 45 citations

Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis

1989 • 45 citations

Cyclosporine a prevents neurological deterioration of patients with SAH ? A preliminary report

1991 • 44 citations

Evidence for pre‐hepatic metabolism of oral cyclosporine in children.

1991 • 44 citations

Cyclosporine treatment of refractory T-cell lymphomas

1993 • 44 citations

Urodilatin: a new peptide with beneficial effects in the postoperative therapy of cardiac transplant recipients

1992 • 44 citations

Treatment of refractory pure red cell aplasia with cyclosporine A: disappearance of IgG inhibitor associated with clinical response

1991 • 44 citations

Cyclosporin metabolism by human gastrointestinal mucosal microsomes.

1992 • 44 citations

Effects of cyclosporine on immunologic mechanisms in psoriasis

1990 • 43 citations

Successful treatment of weber-christian disease by cyclosporin a

1988 • 42 citations

A Review of Assay Methods for Cyclosporin

1992 • 42 citations

Lack of Effect after Local Treatment with a New Ciclosporin Formulation in Recalcitrant Erosive Oral Lichen planus

1992 • 42 citations

Cyclosporine and prednisone therapy for pure red cell aplasia in patients with chronic lymphocytic leukemia

1992 • 42 citations

Cyclosporin A: Alterations of the Cellular Immune Response in S-Antigen-Induced Experimental Autoimmune Uveitis

1983 • 42 citations

Cyclosporine A for the Treatment of New-Onset Insulin-Dependent Diabetes Mellitus

1990 • 42 citations

Prolongation of life in female NZB/NZW (F1) hybrid mice by cyclosporin A.

1985 • 42 citations

Ten year survival of a patient with advanced pulmonary hypertension and mixed connective tissue disease treated with immunosuppressive therapy.

1992 • 42 citations

Measurement of Cyclosporine by Liquid Chromatography and Three Immunoassays in Blood from Liver, Cardiac, and Renal Transplant Recipients

1992 • 41 citations

Topical treatment of severe corneal ulcers with cyclosporin A

1989 • 41 citations

Prolonged remission after cyclosporine therapy in pemphigus vulgaris: Report of two young siblings

1990 • 41 citations

Cyclosporine in the Treatment of Lupus Erythematosus

1986 • 41 citations

Cyclosporin A inhibits acute serum sickness nephritis in rabbits.

1983 • 41 citations

Reversible nephrotoxicity of cyclosporine in rheumatoid arthritis.

1990 • 41 citations

Intractable Epidermolysis bullosa acquisita: Efficacy of Ciclosporin A

1990 • 40 citations

CONTROL OF STEROID‐RESISTANT AUTOIMMUNE HAEMOLYTIC ANAEMIA BY CYCLOSPORINE

1990 • 40 citations

Low-Dose Cyclosporine A in the Treatment of Disabling Morphea

1991 • 40 citations

Induction of Suppressor Cells Specific for AChR in Experimental Autoimmune Myasthenia Gravis

1986 • 40 citations

Cyclosporine in recent onset type I diabetes mellitus

1992 • 40 citations

Sweet's syndrome responding to cyclosporin

1992 • 40 citations

EFFECT OF CYCLOSPORINE ON IMMUNOLOGICALLY MEDIATED DIABETES IN NONOBESE DIABETIC MICE1

1988 • 40 citations

A case of Sweet's syndrome and myelodysplasia: response to cyclosporin

1992 • 40 citations

DISSOCIATION BETWEEN THE IMMUNOSUPPRESSIVE ACTIVITY OF CYCLOSPORINE DERIVATIVES AND THEIR EFFECTS ON INTRACELLULAR CALCIUM SIGNALING IN MESANGIAL CELLS

1989 • 40 citations

REFRACTORY IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP) TREATED WITH CYCLOSPORINE

1985 • 39 citations

Enhanced Integumental and Ocular Amelanosis Following the Termination of Cyclosporine Administration

1987 • 39 citations

Mechanism of action of cyclosporin A and rationale for use in nephrotic syndrome.

1991 • 39 citations

Efficacy of cyclosporin A in systemic sclerosis.

1991 • 39 citations

Assessment of efficacy and acceptability of low dose cyclosporin in patients with rheumatoid arthritis.

1989 • 39 citations

In vitro interferon‐gamma production by cultured T‐cells in severe aplastic anaemia: correlation with granulomonopoietic inhibition in patients who respond to anti‐thymocyte globulin

1988 • 39 citations

Use of cyclosporin in the management of steroid dependent non-necrotising scleritis.

1991 • 38 citations

Circulating osteocalcin in primary biliary cirrhosis following liver transplantation and during treatment with ciclosporin

1990 • 38 citations

Cyclosporin a augments vasoconstrictor-induced rise in intracellular free calcium in rat renal mesangial cells

1988 • 38 citations

Cyclosporin A in the prevention and treatment of experimental autoimmune glomerulonephritis in the brown Norway rat

1991 • 38 citations

Therapy of focal segmental glomerulosclerosis with cyclosporine A

1987 • 38 citations

ALTERATIONS IN RAT PULMONARY MACROPHAGE FUNCTION BY THE IMMUNOSUPPRESSIVE AGENTS CYCLOSPORINE, AZATHIOPRINE, AND PREDNISOLONE

1983 • 38 citations

Cyclosporin a therapy in patients with primary Sjögren's syndrome: results at one year.

1986 • 38 citations

Low-dose Cyclosporine Therapy of Granulomatous Optic Neuropathy and Orbitopathy

1991 • 37 citations

Psoriasis in practice

1991 • 37 citations

Renal side-effects of cyclosporin A with special reference to autoimmune diseases

1990 • 37 citations

A randomised double‐blind trial of cyclosporin and azathioprine in refractory rheumatoid arthritis

1991 • 37 citations

Cyclosporin treatment of a woman with acquired haemophilia due to factor VIII:C inhibitor

1989 • 37 citations

Cyclosporin for Crohn's disease

1987 • 36 citations

Relapsing polychondritis: autoimmunity to type II collagen and treatment with cyclosporin A

1991 • 36 citations

A study of the longterm efficacy and toxicity of cyclosporine A in rheumatoid arthritis.

1991 • 36 citations

Analysis of cloned T cell function. I. Dissection of cloned T cell proliferative responses using cyclosporin A.

1982 • 36 citations

Treatment of Wegener's granulomatosis after renal transplantation: is cyclosporine the preferred treatment?

1990 • 36 citations

Kinetics of T-lymphocyte subsets in the eyes of Lewis rats with experimental autoimmune uveitis

1985 • 35 citations

Effect of cyclosporin a on proteinuria in patients with Alport's syndrome

1992 • 35 citations

Effect of Ciclosporin on Active Heymann Nephritis

1988 • 35 citations

Pathogenesis of cyclosporine-induced hypomagnesemia

1992 • 35 citations

Effects of indomethacin, cyclosporin, cyclophosphamide, and placebo on collagen-induced arthritis of mice

1990 • 35 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. V. Analysis of responding T lymphocyte subpopulations in primary MLR with monoclonal antibodies.

1983 • 35 citations

Treatment of pure red‐cell aplasia and aplastic anaemia with Ciclosporin: Long‐term clinical effects

1989 • 35 citations

Topical cyclosporine for oral bullous disorders

1990 • 35 citations

Progress towards a molecular understanding of cyclosporin A-mediated immunosuppression

1992 • 34 citations

Generalized Myositis in Behçet Disease: Treatment with Cyclosporine

1992 • 34 citations

Low dose cyclosporine in rheumatoid arthritis: a pilot study.

1987 • 34 citations

A study of the interaction between omeprazole and cyclosporine in renal transplant patients.

1993 • 34 citations

Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.

1986 • 34 citations

Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis.

1992 • 34 citations

Topical cyclosporine in chronic benign familial pemphigus (Hailey-Hailey disease)

1992 • 34 citations

Suppression of the hyperacute form of experimental allergic encephalomyelitis by drugs.

1977 • 34 citations

Hypertriglyceridemia in patients with psoriasis treated with cyclosporine

1991 • 34 citations

Sustained renal function loss in psoriasis patients after withdrawal of low-dose cyclosporin therapy

1992 • 34 citations

Intralesional cyclosporin in psoriasis: effects on T lymphocyte and dendritic cell subpopulations

2006 • 33 citations

Cyclosporin A inhibits IL 2-driven proliferation of human alloactivated T cells.

1986 • 33 citations

Effect of cyclosporin A in male autoimmune infertility

1986 • 33 citations

Severe Atopic Eczema: Response to Oral Cyclosporin A

1988 • 33 citations

The effect of cyclosporin a on early and late stages of experimental lupus

1992 • 33 citations

Topical cyclosporine in male pattern alopecia

1990 • 33 citations

Cyclosporine: A Therapy in Inflammatory Eye Disease

1991 • 33 citations

Cyclosporin A responsive chronic severe vesicular hand eczema.

1992 • 33 citations

Cyclosporin A and its Metabolites, Distribution in Blood and Tissues

1991 • 33 citations

Cyclosporin A in asthma therapy: a pharmacological rationale

1992 • 33 citations

Effect of cyclosporine on experimental autoimmune thyroiditis in mice.

1983 • 32 citations

An appraisal of drug interactions with Sandimmun.

1989 • 32 citations

Tolerance of cyclosporine A in children with refractory juvenile rheumatoid arthritis.

1988 • 32 citations

Topical Cyclosporine A Inhibits the Phorbol Ester Induced Hyperplastic Inflammatory Response but not Protein Kinase C Activation in Mouse Epidermis.

1989 • 32 citations

Measurement of cyclosporine and 18 metabolites in blood, bile, and urine by high-performance liquid chromatography.

1988 • 32 citations

Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine.

1992 • 32 citations

Intralesional cyclosporine for psoriasis. Relationship of dose, tissue levels, and efficacy

1992 • 32 citations

Ciclosporin A prevents P2 T cell line-mediated experimental autoimmune neuritis (AT-EAN) in rat

1987 • 31 citations

Effect of Ciclosporin A on Antibody-induced Experimental Glomerulonephritis

1985 • 31 citations

Treatment of Mooren's ulcer with cyclosporin A: report of three cases.

1987 • 31 citations

Oral cyclosporin A is effective in clearing persistent pustulosis palmaris et plantaris.

1990 • 31 citations

The anti-arthritic and immunosuppressive effects of cyclosporine on arthritis induced in the rat by type II collagen.

1984 • 31 citations

Serum transfer of collagen arthritis to cyclosporin-treated, type II collagen-tolerant rats

1985 • 31 citations

Treatment of chronic erythema nodosum leprosum with cyclosporine A produces clinical and immunohistologic remission.

1987 • 31 citations

Effect of Cyclosporin A on Human Neutrophil and Monocyte Function

1985 • 31 citations

Cyclosporin a treatment in children with minimal change nephrotic syndrome and focal segmental glomerulosclerosis

1988 • 30 citations

Effects of immunosuppression with cyclosporine in insulin-dependent diabetes mellitus of recent onset: the Canadian open study at 44 months.

1988 • 30 citations

ENHANCEMENT OF PROCOAGULANT ACTIVITY IN STIMULATED MONONUCLEAR BLOOD CELLS AND MONOCYTES BY CYCLOSPORINE

1987 • 30 citations

Immunosuppression and Cancer: The Ciclosporin Case

1992 • 30 citations

Cyclosporin Pharmacokinetics after Intravenous and Oral Administration in Patients with Crohn's Disease

1992 • 30 citations

Pyoderma gangrenosum in association with erythema elevatum diutinum: report of two cases.

1992 • 30 citations

Pharmacodynamic Monitoring of Cyclosporin

1992 • 30 citations

Effects of FK506, 15-Deoxyspergualin, and Cyclosporine on Experimental Autoimmune Uveoretinitis in the Rat

1990 • 29 citations

Cyclosporin in the Treatment of Steroid-responsive and Steroid-resistant Nephrotic Syndrome in Adults

1988 • 29 citations

Cyclosporine-induced specific unresponsiveness to retinal soluble antigen in experimental autoimmune uveoretinitis

1988 • 29 citations

THE EFFECT OF CYCLOSPORINE ADMINISTRATION ON THE CELLULAR DISTRIBUTION AND CONTENT OF CYCLOPHILIN 1

1992 • 29 citations

Low-dose cyclosporin therapy of ocular inflammation: Preliminary report of a long-term follow-up study

1992 • 29 citations

Assessment of viral and immune factors in EMC virus-induced diabetes: effects of cyclosporin A and interferon.

1983 • 29 citations

Cyclosporin therapy in Mooren's ulcer.

1987 • 29 citations

Human polymorphonuclear leukocyte interaction with cyclosporine A

1984 • 28 citations

Cyclosporine in Lamellar Ichthyosis

1989 • 28 citations

Cyclosporine blocks the activation of antigen-dependent cytotoxic T lymphocytes directly by an IL-2-independent mechanism.

1988 • 28 citations

Cyclosporin Therapy for Prevention and Cure of IDDM: Epidemiological Perspective of Benefits and Risks

1990 • 28 citations

Cyclosporine Therapy for Bullous Erythema Multiforme

1990 • 28 citations

Effects of Cyclosporin A on Autoimmune Disease in MRL/1 and BXSB Mice

1986 • 28 citations

Ciclosporin in Localized and Systemic Scleroderma – A Clinical Study

1990 • 28 citations

Long-term low-dose cyclosporin A in steroid dependent nephrotic syndrome of childhood

1992 • 28 citations

Cyclosporine treatment for dermatomyositis/polymyositis.

1993 • 28 citations

Results of a one-year open trial of cyclosporine in ten patients with severe myasthenia gravis.

1988 • 27 citations

THE EFFECT OF H-2 COMPATIBILITY ON PANCREATIC BETA CELL SURVIVAL IN THE NONOBESE DIABETIC MOUSE

1988 • 27 citations

[Treatment of severe alopecia areata with topical applications of cyclosporin A].

1987 • 27 citations

Myocardial magnesium depletion associated with prolonged hypomagnesemia: A longitudinal study in heart transplant recipients

1992 • 27 citations

Effects of cyclosporine in spontaneous, posterior uveitis

1986 • 27 citations

Inhibition of Vascular Permeability Factor Production by Ciclosporin in Minimal Change Nephrotic Syndrome

1992 • 27 citations

Influence of systemic cyclosporin A on interleukin-2 and epidermal growth factor receptor expression in psoriatic skin lesions.

1989 • 27 citations

Cyclosporin A treatment of an induced attack in a chronic relapsing model of experimental allergic encephalomyelitis

1986 • 27 citations

Skin collagen from scleroderma patients before and after cyclosporin A treatment

1988 • 26 citations

New Treatment Approaches to Myasthenia Gravis

1990 • 26 citations

Immunohistologic evaluation of the effect of cyclosporine treatment on the lichen planus immune infiltrate

1991 • 26 citations

Pharmacologic effects on the expression of class II histocompatibility antigen in experimental endotoxin-induced uveitis

1987 • 26 citations

Contrasting response to cyclosporin in refractory nephrotic syndrome.

1989 • 26 citations

Cyclosporin A Therapy for Mycosis Fungoides

1987 • 26 citations

[Cyclosporin A in the therapy of inflammatory dermatoses].

1992 • 26 citations

Preventive and therapeutic effects of cyclosporin and valine2-dihydro-cyclosporin in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat.

1988 • 26 citations

Heart and Heart-Lung Transplantation

2015 • 26 citations

Rapid response of von Zumbusch psoriasis to cyclosporine

1990 • 26 citations

Alloantigen-specific suppressor T cells are not inhibited by cyclosporin A, but do require IL 2 for activation.

1986 • 26 citations

Cyclosporine effects on optic nerve and retinal vasculitis in Behcet's disease

1992 • 25 citations

The autoimmune response in active Heymann's nephritis in Lewis rats is regulated by T-lymphocyte subsets

1985 • 25 citations

Juvenile dermatomyositis treated with cyclosporine

1990 • 25 citations

Cyclosporin reduces proteinuria in rats with aminonucleoside nephrosis

1992 • 25 citations

Cyclosporine in the treatment of cutaneous T cell lymphoma

1990 • 25 citations

Successful treatment of musk ketone-induced chronic actinic dermatitis with cyclosporine and PUVA

1992 • 25 citations

Deposition of nine metabolites of cyclosporine in human tissues, bile, urine, and whole blood.

1988 • 25 citations

Treatment of Pemphigus vulgaris with Ciclosporin

1990 • 25 citations

EAU in the guinea pig: inhibition of cell-mediated immunity and Ia antigen expression by cyclosporin A.

1987 • 25 citations

Steroid-resistant bullous pemphigoid treated with cyclosporin A

1991 • 25 citations

Treatment of adults with severe aplastic anemia: Primary therapy with antithymocyte globulin (ATG) and rescue of ATG failures with bone marrow transplantation

1992 • 25 citations

Successful treatment of autoimmunity in (NZB X NZW)F1 mice with cyclosporin and (Nva2)-cyclosporin: I. Reduction of autoantibodies.

1986 • 25 citations

ALOPECIA UNIVERSALIS TREATED WITH ORAL CYCLOSPORINE A AND PREDNISOLONE: IMMUNOLOGIC STUDIES

1992 • 25 citations

Cyclosporin A treatment of young children with newly-diagnosed Type 1 (insulin-dependent) diabetes mellitus

1992 • 25 citations

IL-4 bypasses the immune suppressive effect of cyclosporin A during the in vitro induction of murine cytotoxic T lymphocytes.

1988 • 25 citations

Cyclosporin‐a for the treatment of pure red cell aplasia in a patient with chronic lymphocytic leukemia

1987 • 25 citations

Evolution of Ciclosporin Nephrotoxicity in Patients Treated for Autoimmune Uveitis

1989 • 25 citations

Successful treatment of aggressive pyoderma gangrenosum with pulse steroids and chlorambucil

1992 • 24 citations

Resolution of atopic dermatitis in a patient treated with cyclosporine

1989 • 24 citations

Treatment of Crohn's disease in relapse with cyclosporin A

1988 • 24 citations

Immunologic parameters of response in patients with rheumatoid arthritis treated with cyclosporin a

1990 • 24 citations

Recent Advances in Cyclosporine Pharmacokinetics

1991 • 24 citations

Cyclosporine maintenance therapy in psoriasis.

1988 • 24 citations

Optimisation of Immunosuppressive Therapy Using Pharmacokinetic Principles

1992 • 24 citations

Specific Enzyme-Multiplied Immunoassay and Fluorescence Polarization Immunoassay for Cyclosporin Compared with Cyclotrac [125I]Radioimmunoassay

1992 • 24 citations

Arachidonic acid metabolism in human neutrophils: Lack of effect of cyclosporine A

1986 • 23 citations

Effect of Cyclosporin on Pancreatic Events and Development of Diabetes in BB/Edinburgh Rats

1990 • 23 citations

A patient with a spontaneous factor VIII:C autoantibody: successful treatment with cyclosporine.

1988 • 23 citations

Management of Nephrotic Syndrome in Childhood

1991 • 23 citations

Acute Cyclosporin Overdose A Review of Present Clinical Experience

1991 • 23 citations

SEVERE ACUTE FORM OF ADULT DERMATOMYOSITIS TREATED WITH CYCLOSPORINE

1992 • 23 citations

Cyclosporine: Nephrotoxic effects and guidelines for safe use in patients with rheumatoid arthritis

1992 • 23 citations

Long-term Treatment of Minimal-change Nephrotic Syndrome with Cyclosporin: A Control Biopsy Study

1988 • 22 citations

Endocrine-Metabolic Function in Remission-Phase IDDM During Administration of Cyclosporine

1991 • 22 citations

Cyclosporine Inhibits the Expression of Receptors for Interleukin 2 and Transferrin on Mitogen-Activated Human T Lymphocytes

1986 • 22 citations

A short-term controlled trial of cyclosporine A in IgA nephropathy.

1988 • 22 citations

Coxsackievirus B-3 myocarditis. T-cell autoimmunity to heart antigens is resistant to cyclosporin-A treatment.

1986 • 22 citations

Effects of cyclosporine on T-cell subsets in experimental autoimmune uveitis.

1985 • 22 citations

Cyclosporin in Steroid-Resistant Auto-Immune Haemolytic Anaemia

1991 • 22 citations

Long-term treatment of psoriasis with cyclosporin A-side-effects, minimal effective dose and cyclosporin blood levels

1991 • 22 citations

SRI 62–834, a cyclic ether analogue of the phospholipid ET-18-OCH3, displays long-lasting beneficial effect in chronic relapsing experimental allergic encephalomyelitis in the lewis rat. Comparison with cyclosporin and (Val2)-dihydrocyclosporin effects in clinical, functional and histological studies

1992 • 22 citations

Cyclosporine for Pyoderma Gangrenosum

1993 • 22 citations

Placebo-controlled study of psoriasis patients treated topically with a 10% cyclosporine gel

1990 • 22 citations

Failure of reticular erythematous mucinosis to respond to cyclosporine

1992 • 22 citations

CYCLOSPORIN A IN ADULT‐ONSET CYCLIC NEUTROPENIA

1988 • 22 citations

Combination-therapy cyclosporin-A-etretinate for psoriasis

1990 • 22 citations

Acute iritis associated with primary sjögren's syndrome and high‐titer anti—SS‐A/Ro and anti—SS‐B/La antibodies. Treatment with combination immunosuppressive therapy

1992 • 21 citations

Is cyclosporine effective in preventing recurrence of immune-mediated glomerular disease after renal transplantation?

1988 • 21 citations

Effect of cyclosporine A on mercury-induced autoimmune glomerulonephritis in the Brown Norway rat.

1986 • 21 citations

Persistent light reaction. Successful treatment with cyclosporin A.

1988 • 21 citations

Cyclosporine for the treatment of granulocytopenia in Felty's syndrome

1991 • 21 citations

Differential effects of cyclosporine and etretinate on serum cytokine levels in patients with psoriasis

1992 • 21 citations

The influence of cyclosporin A on the induction of experimental autoimmune thyroid disease in the PVG/c rat.

1985 • 21 citations

Pneumocystis carinii pneumonia following cyclosporine A and methotrexate treated rheumatoid arthritis.

1992 • 21 citations

The effect of cyclosporin A on the interstitial mononuclear cell infiltration and the induction of Heymann's nephritis

1990 • 20 citations

Cyclosporin for central nervous system sarcoidosis

1988 • 20 citations

[Cyclosporin A in the treatment of pemphigus foliaceus and pemphigus erythematosus].

1986 • 20 citations

Immunological and immunopathological aspects of opsin-induced uveoretinitis

1987 • 20 citations

Pharmacokinetic study of cyclosporin A (Sandimmun) in patients with primary biliary cirrhosis.

1984 • 20 citations

Cyclosporine versus Azathioprine in the Treatment of Multiple Sclerosis: 12-Month Clinical and Immunological Evaluation

1990 • 20 citations

The Role of Cyclosporine A in the Treatment of Pemphigus Erythematosus

1991 • 20 citations

Efficacy of cyclosporin A for idiopathic pulmonary fibrosis

1990 • 20 citations

Hemolytic uremic syndrome in a patient with systemic sclerosis treated with cyclosporin A.

1992 • 20 citations

Cyclosporin A inhibits autoimmune experimental tubulointerstitial nephritis

1987 • 20 citations

CYCLIC IDIOPATHIC PURE ACQUIRED AMEGAKARYOCYTIC THROMBOCYTOPENIC PURPURA: A PATIENT TREATED WITH CYCLOSPORIN A

1989 • 20 citations

Cyclosporin A in a pregnant patient affected with systemic lupus erythematosus

1992 • 20 citations

Review article: the pharmacological implications of leucocyte–endothelial cell interactions in Crohn's disease

1991 • 20 citations

Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata.

1991 • 20 citations

Uveitis: management

1991 • 20 citations

Remission in skin infiltrate of a patient with mycosis fungoides treated with cyclosporine

1985 • 20 citations

Therapeutic Efficacy of Oral Low-Dose Cyclosporin A in Severe Psoriatic Arthritis

1993 • 20 citations

Post-endoscopy arterial oxygen desaturation and pulse oximetry.

1991 • 20 citations

Cyclosporin a therapy in paraprotein-associated neuropathy

1992 • 19 citations

Ciclosporin (Sandimmun�) Therapy: Experience in the Treatment of Pars Planitis and Present Therapeutic Guidelines

2015 • 19 citations

Clinical effects of cyclosporin in dermatomyositis

1990 • 19 citations

Combined Use of Cyclosporine and Ketoconazole in the Treatment of Endogenous Uveitis

1992 • 19 citations

Severe neutropenia associated with large granular lymphocyte lymphocytosis: Successful control with cyclosporin A

1989 • 19 citations

Effects of cyclosporin A on a kidney epithelial cell line (LLC-PK1).

1987 • 19 citations

Cyclosporin A in the treatment of CLL associated PRCA and bone marrow hypoplasia.

1988 • 19 citations

The influence of cyclosporin A on the vascular permeability of the pancreatic islets and on diabetes induced by multiple low doses of streptozotocin in the mouse

1988 • 19 citations

Cyclosporin A for the treatment of aplastic anemia refractory to antithymocyte globulin

1987 • 19 citations

Combination of cyclosporine A and topical corticosteroid in the treatment of psoriasis.

1988 • 19 citations

RECALCITRANT PYODERMA GANGRENOSUM RESPONSIVE TO CYCLOSPORINE

1993 • 19 citations

Experimental erythrocyte autoimmunity prevented by suppressor T cells in mice treated with Cyclosporin-A

1983 • 19 citations

Cyclosporin a suppresses proliferation of renal mesangial cells in culture

1988 • 18 citations

Low‐dose cyclosporin for Crohn's disease: implications for clinical trials

1989 • 18 citations

EFFECTS OF CYCLOSPORIN A ON HUMAN GRANULOPOIESIS IN VITRO

1980 • 18 citations

Effect of the immune modulating agents cyclophosphamide, methotrexate, hydrocortisone, and cyclosporin A on an animal model of granulomatous bowel disease.

1990 • 18 citations

Treatment of pyoderma gangrenosum with cyclosporin A

1991 • 18 citations

Cyclosporin A treatment for diamond‐blackfan anemia

1992 • 18 citations

Treatment of endogenous uveitis with cyclosporine A.

1988 • 18 citations

Cyclosporine Treatment of Severe Recalcitrant Pyoderma Gangrenosum in a Patient With Takayasu's Arteritis

1991 • 18 citations

EFFECT OF CYCLOSPORINE ON THE ANTIGEN-PRESENTING FUNCTION OF HUMAN AND MURINE ACCESSORY CELLS1

1988 • 18 citations

Renal haemodynamics of cyclosporin A nephrotoxicity in children with juvenile dermatomyositis

1991 • 18 citations

Cyclosporin A in aplastic anemia — report of a workshop

1992 • 18 citations

Effect of a new topical cyclosporin formulation on human allergic contact dermatitis

1992 • 17 citations

The enigma of cyclosporin A treatment for psoriasis: systemic efficacy versus topical non-responsiveness. A review.

1992 • 17 citations

Acrodermatitis continua responding to cyclosporin therapy

1992 • 17 citations

Severe neutropenia in a patient with large granular lymphocytosis: prolonged successful control with cyclosporin A.

1991 • 17 citations

Cyclosporine therapy for severe systemic sclerosis associated with the anti-Scl-70 autoantibody

1990 • 17 citations

Successful treatment of autoimmunity in (NZB X NZW)F1 mice with cyclosporin and (Nva2)-cyclosporin: II. Reduction of glomerulonephritis.

1986 • 17 citations

Prevention of diabetes in BB rats by intermittent administration of cyclosporine.

1987 • 17 citations

Prevention of adjuvant arthritis by cyclosporine in rats

1992 • 17 citations

Interaction of bromocriptine and cyclosporine in insulin dependent diabetes mellitus: Results from the Canadian open study

1990 • 17 citations

Cyclosporin A and prednisolone do not inhibit the expression of high-affinity receptors for interleukin 2.

1988 • 17 citations

Myasthenia gravis treated with ciclosporin

1988 • 17 citations

Treatment of aplastic anemia with cyclosporin A, methylprednisolone, and antithymocyte globulin

1986 • 17 citations

Immunological and Metabolic Concomitants of Cyclosporin Prevention of Diabetes in BB Rats

1987 • 16 citations

Treatment of graves' ophthalmopathy with cyclosporin a

1985 • 16 citations

A Preliminary Multicentre Study of the Treatment of Recently Diagnosed Type 1 Diabetes by Combination Nicotinamide-Cyclosporin Therapy

1990 • 16 citations

[Results of cyclosporin treatment of severe, chronic psoriasis vulgaris].

1989 • 16 citations

Effects of Cyclosporin A on Functions of Specific Murine T Cell Clones: Inhibition of Proliferation, Lymphokine Secretion and Cytotoxicity

1986 • 16 citations

More about omeprazole-cyclosporine interaction.

1993 • 16 citations

Virus-induced Murine Diabetes: Enhancement by Immunosuppression

1985 • 16 citations

Cyclosporin for Inflammatory Pseudotumour.

1992 • 16 citations

Omeprazole-cyclosporin interaction.

1991 • 16 citations

Cyclosporin-A treatment of experimental allergic encephalomyelitis: Changes in immunological regulation and blood-CSF barrier function

1986 • 16 citations

Cyclosporin enhances diabetes induced by low-dose streptozotocin treatment in mice

1985 • 16 citations

Alopecia totalis: Is treating nonresponder patients useful?

1991 • 16 citations

The effect of cyclosporin on renal function

1992 • 16 citations

Cyclosporine and Dexamethasone Inhibit T-Lymphocyte MHC Class II Antigens and IL-2 Receptor Expression in Experimental Autoimmune Uveitis

1987 • 16 citations

Differential effects of cyclosporins A and G on functional activation of a T-helper-lymphocyte line mediating experimental autoimmune uveoretinitis

1988 • 16 citations

Kidney biopsy findings in cyclosporine-treated patients with insulin-dependent diabetes mellitus

1991 • 16 citations

Cyclosporin maintenance therapy for severe atopic dermatitis.

1991 • 16 citations

Adoptive Immunotherapy of Diabetes in Autologous Nonobese Diabetic Mice With Lymphoid Cells Ex Vivo Exposed to Cyclosporin Plus Interleukin 2

1988 • 15 citations

Effect of the Immunosuppressive Agent, Ciclosporin, on Experimental Immune Complex Glomerulonephritis in Rats

1991 • 15 citations

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation

1992 • 15 citations

The pharmacokinetics of cyclosporine A in uremic patients.

1986 • 15 citations

Cyclosporine-induced alterations of humoral response in experimental autoimmune uveitis.

1984 • 15 citations

Cyclosporin‐A therapy of pure red cell aplasia in a patient with B‐cell chronic lymphocytic leukemia

1989 • 15 citations

Suppression by Cyclosporin A of Anti-GBM Nephritis in Rats.

1992 • 15 citations

Urticated annular erythema: a new manifestation of Sjogren's syndrome

1993 • 15 citations

Remission of Sézary´s syndrome with cyclosporin A. Mild capillary leak syndrome as an unusual side effect

1986 • 15 citations

COMPARISON OF SPECIFIC RADIOIMMUNOASSAYS FOR CYCLOSPORINE

1989 • 15 citations

Cyclosporin A induces long-term unresponsiveness in mercuric chloride-induced autoimmune glomerulonephritis.

1988 • 15 citations

Treatment of chronic relapsing inflammatory demyelinating polyneuropathy by cyclosporin A and plasma exchange

1990 • 15 citations

Cyclosporin A in nontransplant-related liver disease.

1989 • 15 citations

Cyclosporine May Alleviate B Symptoms and Induce a Remission of Heavily Pretreated Hodgkin Disease: A Preliminary Report

1987 • 15 citations

Interaction between cyclosporine and felodipine in renal transplant recipients.

1992 • 15 citations

Properties of Suppressor Cells Induced to Acetylcholine Receptor Using Cyclosporin A^a

1987 • 14 citations

Recalcitrant pyoderma gangrenosum-two cases successfully treated with cyclosporin A

1992 • 14 citations

Eruptive Lichen Planus

1992 • 14 citations

Cyclosporine in Steroid‐Resistant Diamond‐Blackfan Anaemia

1988 • 14 citations

Retina S Antigen-Induced Uveitis

1986 • 14 citations

Generalized essential telangiectasia.

1991 • 14 citations

Insulin requirements and residual beta-cell function 12 months after concluding immunotherapy in type I diabetic patients treated with combined azathioprine and thymostimulin administration for one year

1990 • 14 citations

Modulation of HLA-DR Expression on Retroocular Fibroblasts from Patients with Active Thyroid-Related Ophthalmopathy: In vitro Effects of Agents Used in the Management of Hyperthyroidism and Ophthalmopathy

2009 • 14 citations

Effect of cyclosporin A on autoimmune tubulointerstitial nephritis in the brown Norway rat.

1987 • 14 citations

Cyclosporin Treatment of a Patient with Severe Systemic Juvenile Rheumatoid Arthritis

1988 • 14 citations

The synergistic immunosuppressive potential of cyclosporin metabolite combinations

1992 • 13 citations

Effect of cyclosporine and cyclosporine plus prednisone in primary biliary cirrhosis.

1988 • 13 citations

Cyclosporin A enhances Streptozocin-induced diabetes in CD-1 mice

1987 • 13 citations

Molecular mode of action of cyclosporin and FK506in human thymocytes

1992 • 13 citations

Cyclosporine trials in diabetes: updated results of the French experience.

1988 • 13 citations

Glomerulonephritis in NZB/W mice: therapeutic effect of cyclosporine.

1986 • 13 citations

Resolution of type 1 reaction in multibacillary Hansen's disease as a result of treatment with cyclosporine.

1992 • 13 citations

Cyclosporin monitoring: Its role in autoimmune indications

1992 • 13 citations

Cyclosporin A and anti-glomerular basement membrane antibody glomerulonephritis in rats.

1988 • 13 citations

Dermatomyositis Treated with Cyclosporin

1991 • 12 citations

Functional consequences and risk factors of chronic cyclosporine nephrotoxicity in type I diabetes trials.

1988 • 12 citations

Suppression of actively induced and passively transferred experimental allergic neurities by cyclosporin A

1990 • 12 citations

Effect of cyclosporin A (CyA) on the in vitro growth of hemopoietic progenitors from normal marrow.

1985 • 12 citations

Cyclophilin binding: a receptor-mediated approach to monitoring cyclosporine immunosuppressive activity following organ transplantation.

1990 • 12 citations

CYCLOSPORIN A INDUCED REMISSION OF CD4 + T‐CLL ASSOCIATED WITH EOSINOPHILIA AND FASCIITIS

1992 • 12 citations

In vivo Effects of Cyclosporin A: Abrogation of the Induction of Experimental Allergic Orchitis and Sparing of the Generation of Suppressor Cells

1985 • 12 citations

Open Noncontrolled Multicenter Long-Term Trial with Ciclosporin in Endogenous Non-Infectious Uveitis

1991 • 12 citations

Therapeutic effect of cyclosporine in thrombocytopenia associated with autoimmune disease.

1988 • 12 citations

Cyclosporine nephrotoxicity in rheumatoid arthritis: no effect of short term misoprostol treatment.

1992 • 12 citations

Successful treatment of rheumatoid arthritis with low-dose cyclosporine A.

1988 • 12 citations

Comparison of the efficacy of unilateral, bilateral, and oral cyclosporine in experimental immunogenic uveitis in rabbits.

1988 • 12 citations

Cutaneous malignancy related to cyclosporin A therapy

1993 • 12 citations

Animal models utilized in the research of autoimmune disease control: experimental therapy of glomerulonephritis in NZB/W F1 mice.

1987 • 11 citations

Severe systemic vascular necrosis in cyclosporin-treated rabbits with acute serum sickness.

1984 • 11 citations

Cyclosporine in the treatment of aplastic anaemia and pure red-cell aplasia.

1989 • 11 citations

Cyclosporine as monotherapy for polymyositis?

1988 • 11 citations

[Cyclosporine A inhibits allergen-induced late asthmatic response and increase of airway hyperresponsiveness in guinea pigs].

1991 • 11 citations

Cyclosporine A treatment in four cases of aplastic anemia

1987 • 11 citations

Safety and tolerability of cyclosporin A (Sandimmun) in idiopathic nephrotic syndrome. Collaborative Study Group of Sandimmun in Nephrotic Syndrome.

1991 • 11 citations

Comparative study of effects of cyclosporins A and G on collagen arthritis in mice

1992 • 11 citations

Immunosuppressive treatment of Graves' ophthalmopathy with cyclosporine A.

1988 • 11 citations

Monitoring cyclosporin: is it still important?

1991 • 11 citations

Effect of cyclosporin A on low-dose streptozotocin diabetes in mice.

1985 • 11 citations

Protection of glomerular filtration rate by the thromboxane receptor antagonist L655,240 during low dose cyclosporine administration

1992 • 11 citations

Treatment of pure red cell aplasia with ciclosporin: Suppression of activated T suppressor/cytotoxic and NK‐like cells in marrow and blood correlates with haematological response

1988 • 11 citations

Atopic Dermatitis: Recent Therapeutic Advances

1992 • 11 citations

Suppression of Experimental Autoimmune Uveitis in Guinea Pigs by Ethylenediamine Tetra-Acetic Acid, Corticosteroids, and Cyclosporin

1987 • 11 citations

Ocular bioavailability of cyclosporine after oral administration.

1988 • 11 citations

Identification of a sulfate conjugate of cyclosporin.

1989 • 10 citations

Cyclosporin A mediated immunosuppressionin vitro: effect on high affinity interleukin-2 receptor expression and -turnover

1989 • 10 citations

Unsatisfactory effect of cyclosporin A treatment in Crohn's disease: a report of five cases

1989 • 10 citations

Determination of cyclosporine by a competitive binding assay with cyclophilin

1991 • 10 citations

Ciclosporin in Goodpasture’s Syndrome

1992 • 10 citations

Treatment of acute exacerbations in early multiple sclerosis: cyclosporin A or prednisolone?

2009 • 10 citations

Resistant severe psoriasis controlled with systemic cyclosporine therapy.

1988 • 10 citations

Sulfadiazine therapy for toxoplasmosis in heart transplant recipients decreases cyclosporine concentration

1992 • 10 citations

Cyclosporine therapy for refractory Langerhans cell histiocytosis [letter; comment]

1991 • 10 citations

Selection of an optimal assay method for monitoring cyclosporine therapy.

1990 • 10 citations

Treatment of the nephrotic syndrome with cyclosporin A

1992 • 10 citations

Effect of cyclosporine on urinary kallikrein excretion in patients with rheumatoid arthritis.

1988 • 10 citations

Parameters of calcium metabolism during a pilot study of cyclosporin A in patients with symptomatic primary biliary cirrhosis.

1991 • 10 citations

Topically applied cyclosporin for modulation of induced immunogenic uveitis in rabbits.

1988 • 10 citations

Results of an open trial of cyclosporine in a group of steroidodependent myasthenic subjects

1990 • 10 citations

Eosinophilic fasciitis and severe aplastic anemia: favorable response to either antithymocyte globulin or cyclosporine A in blood and skin disorders.

1988 • 10 citations

The effect of cyclosporine in idiopathic nephrotic syndrome resistant to immunosuppressive therapy.

1988 • 10 citations

Cyclosporins past, present, and future.

1992 • 9 citations

Frequency of human alloantigen-reactive T lymphocytes. III. Evidence that cyclosporine has an inhibitory effect on human CTL and CTL precursors, independent of CsA-mediated helper T cell dysfunction.

1988 • 9 citations

Wegener's granulomatosis—use of cyclosporin‐A: a case report

1990 • 9 citations

Cyclosporin for treatment of life‐threatening alloimmunization

1990 • 9 citations

Inhibitory effect of cyclosporin A on erythroid and stromal colonies

1991 • 9 citations

SUPPRESSIVE EFFECT OF CYCLOSPORIN A ON THE INDUCTION OF CHRONIC SERUM SICKNESS NEPHRITIS IN THE RAT

1988 • 9 citations

Effect of cyclosporine on in situ immune complex glomerulonephritis.

1986 • 9 citations

Decreased hospitalization and increased height velocity in focal segmental glomerulosclerosis responsive to ciclosporin A.

1991 • 9 citations

[The macula in Adamantiades-Behçet disease].

1989 • 9 citations

Cyclosporine in Neurological Autoimmune Disease

1988 • 9 citations

Cyclosporine A Inhibits the Secretion of Certain Anterior Pituitary Hormones in Patients with Nephrotic Syndrome.

1992 • 9 citations

Cyclosporin therapy for steroid resistant nephrotic focal glomerulosclerosis.

1990 • 9 citations

Probability of remission in individual in early adult insulin dependent diabetic patients. Results from the Cyclosporine Diabetes French Study Group.

1990 • 9 citations

Cyclosporine therapy for psoriasis: A cell cycle-derived dosing schedule

1992 • 9 citations

Cyclosporine therapy in chronic slowly progressive polymyositis--preliminary report of clinical results in three patients.

1988 • 9 citations

Severe aplastic anemia (SAA): Response to cyclosporin A (CyA) in vivo and in vitro

1991 • 9 citations

Cyclosporine Therapy of Guinea-Pig Autoimmune Uveoretinitis Induced with Autologous Retina

1986 • 8 citations

[Low dose cyclosporin treatment for ocular lesions of Behçet's disease].

1992 • 8 citations

Modulation by cyclosporin-A of mononuclear cell distribution during experimental allergic encephalomyelitis

1984 • 8 citations

The use of cyclosporin a in adult nephrotic syndrome: Nine cases and literature review

1990 • 8 citations

Effect of cyclosporine on proteinuria in chronic serum sickness in rats.

1986 • 8 citations

Ketoconazole and High-Dose Methylprednisolone Predisposing to Cyclosporine-lnduced Seizures: Report of 3 Cases

1992 • 8 citations

Cyclosporin reduces renal prostanoid excretion in type 1 diabetic patients

1992 • 8 citations

Resolution of type 1 reaction in multibacillary Hansen's disease as a result of treatment with cyclosporine.

1992 • 8 citations

Oral pharmacokinetics of cyclosporin in patients with primary biliary Cirrhosis and patients with skin diseases

1992 • 8 citations

Cyclosporin A levels in suction-blister fluid of patients with psoriasis treated systemically

1990 • 8 citations

Selection of an optimal assay method for monitoring cyclosporine therapy.

1990 • 8 citations

Cyclosporine‐induced renal morphologic and immunohistologic changes in patients with chronic uveitis

1991 • 8 citations

Cyclosporine A allows the expression of high affinity interleukin 2 binding sites on anti-T-cell antibody activated human T lymphocytes.

1987 • 7 citations

Morphological characteristics of the endocrine pancreas in alloxan diabetes after cyclosporin A administration.

1991 • 7 citations

Cyclosporin A in steroid-sensitive nephrotic syndrome with frequent relapses

1987 • 7 citations

Cyclosporine therapy in chronic inflammatory demyelinating polyradiculoneuropathy--a preliminary report of clinical results in two patients.

1988 • 7 citations

Effect of cyclosporin A on T cell clones from severe aplastic anemia: differential sensitivity of TNF and GM-CSF production.

1992 • 7 citations

Cyclosporine in the treatment of azathioprine-induced red cell aplasia following renal transplantation

1992 • 7 citations

Cyclosporine A and cyclosporine G enhance IgG rheumatoid factor production in MRL/lpr mice.

1988 • 7 citations

Ciamexon in the low dose streptozotocin induced diabetes of mice.

1987 • 7 citations

Cyclosporine A treatment in four cases with corneal melting syndrome.

1988 • 7 citations

Experimental Autoimmunity

2015 • 7 citations

Immunomodulation Therapy for Severe Aplastic Anemia -ALG Versus ALG Plus Cyclosporin A-

1989 • 6 citations

Treatment of Graves' Ophthalmopathy with Cyclosporin A

1986 • 6 citations

Therapy of aplastic anemia with sequential antithymocyte globulin and cyclosporin

1991 • 6 citations

Pharmacokinetics of cyclosporine in patients with primary biliary cirrhosis.

1988 • 6 citations

[Cyclosporin A in chronic active hepatitis. Results of a pilot study of 20 patients].

1988 • 6 citations

Erfolgreiche Behandlung der primären biliären Zirrhose mit Ciclosporin

2008 • 6 citations

Immunosuppression in autoimmune disease: the double-edged sword.

1987 • 6 citations

Low-dose cyclosporine A in severe psoriasis.

1988 • 6 citations

Immunologic effects in patients with psoriatic arthritis treated with cyclosporine A.

1992 • 6 citations

Penetration of cyclosporin into synovial fluid in rheumatoid arthritis

1989 • 6 citations

Cyclosporin for Crohn??s Disease?

1992 • 6 citations

Therapeutic Strategies for Myasthenia Gravis

1991 • 6 citations

Fatal septicaemia due to Listeria monocytogenes in a patient with systemic lupus erythematosus receiving cyclosporin and high prednisone doses.

1992 • 6 citations

Treatment of severe Mooren's ulcer with cyclosporin A eyedrops.

1992 • 6 citations

Renal morphology after cyclosporin A therapy in rheumatoid arthritis patients. International Kidney Biopsy Registry of Cyclosporin (Sandimmun) in Autoimmune Diseases.

1993 • 6 citations

Thyroid eye disease--medical or surgical therapy?

1991 • 6 citations

Pharmacokinetics and nephrotoxicity of cyclosporine.

1991 • 6 citations

Treatment of idiopathic nephrotic syndrome withcyclosporin in children. Preliminary results of growth data in long term use

1992 • 5 citations

The effect of cyclosporin a on cationized bovine serum albumin‐induced nephropathy in NZW rabbits

1992 • 5 citations

Treatment of Cutaneous T-cell Lymphoma with Cyclosporin A: Case Report and Literature Review

1991 • 5 citations

[Value of cyclosporin A in dermatomyositis in a child].

1988 • 5 citations

Cyclosporine in rheumatoid arthritis: Beyond experimentation

1992 • 5 citations

Treatment of platelet‐alloimmunization with cyclosporin a in a patient with aplastic anemia

1990 • 5 citations

Influence of topically applied cyclosporin A in various vehicles on patch test reactions

1992 • 5 citations

Pharmacokinetics of oral cyclosporin A in diabetic children and adolescents

1990 • 5 citations

Die Behandlung des Goldmann-Favre-Syndroms mit Cyclosporin A und Bromocriptin

1991 • 5 citations

Cyclosporine A, experimental autoimmune uveitis, and major histocompatibility class II antigen expression of cultured retinal pigment epithelial cells.

1988 • 5 citations

Antiproteinuric effect of cyclosporine A in passive antiglomerular basement membrane nephritis in the mouse.

1988 • 5 citations

Influences of Ciclosporin Pretherapyon 90% Hepatectomized Rats

1992 • 5 citations

The Use of Low Dose Cyclosporin A in a Case of Recalcitrant Erythrodermic Psoriasis

1988 • 5 citations

Treatment of chronic neutropenia of childhood responsive to cyclosporin A in vitro and in vivo.

1992 • 5 citations

Treatment of chronic neutropenia of childhood responsive to cyclosporin A in vitro and in vivo.

1992 • 5 citations

[Efficacy of cyclosporin in corticoid-dependent splenectomy-resistant lupus with hematologic manifestations].

1986 • 4 citations

Response to cyclosporine administration at onset of diabetes in BB rats.

1987 • 4 citations

Effectiveness of low dose cyclosporine in acquired aplastic anaemia with severe neutropenia.

1992 • 4 citations

[Treatment of severe aplastic anemia with a cyclosporin-corticosteroid combination].

1987 • 4 citations

[Cyclosporin A in dermatomyositis].

1984 • 4 citations

Cyclosporin A (CsA) Prevents the Generation of Mature Thymic α/βT Cells but Spares γ/δ T Lymphocytes

1991 • 4 citations

[Successful treatment of autoimmune hemolytic anemia with cyclosporin A].

1986 • 4 citations

Immunointervention in primary biliary cirrhosis: an overview

1992 • 4 citations

Therapie der okulären Form des Morbus Behçet mit Cyclosporin A

1990 • 4 citations

DRAMATIC IMPROVEMENT OF PURE RED CELL APLASIA REFRACTORY TO COMBINED CYCLOSPORINE AND PREDNISOLONE THERAPY INDUCED BY PREDNISOLONE DOSE ESCALATION

1991 • 4 citations

[Cyclosporin A--dermatologic indications].

1990 • 4 citations

Differential effect of cyclosporin-A on the mixed-lymphocyte culture-induced proliferative and cytotoxic responses of T lymphocytes with different cell densities

1986 • 3 citations

Ciclosporin treatment in experimental autoimmune myasthenia gravis.

1988 • 3 citations

[Comparison of high-dose immunoglobulin and cyclosporine in newly diagnosed diabetic children].

1991 • 3 citations

3H-Cyclosporine Internalization and Secretion by Human Fetal Pancreatic Islets

1988 • 3 citations

Ciclosporin-Behandlung bei Uveitis*

1986 • 3 citations

Cyclosporine and other therapy-resistant nephrotic syndrome.

1988 • 3 citations

Antigen-specific suppressor cells induced by cyclosporine.

1988 • 3 citations

Cyclosporine a in Five Children with Severe Aplastic Anemia

1990 • 3 citations

[The use of cyclosporin A in treating partial red-cell aplasia of the bone marrow and aplastic anemia].

1992 • 2 citations

Effective treatment with cyclosporin A in amegacaryocytic purpura followed by ischemic complications.

1990 • 2 citations

Progression of membranous glomerulopathy during cyclosporin A.

1992 • 2 citations

Suppression of Experimental Allergic Neuritis by Cyclosporin A

1988 • 2 citations

[A patient with acute dermatomyositis successfully treated with Ciclosporin].

1986 • 2 citations

[L-tryptophan-associated chronic eosinophilia-myalgia syndrome treated with cyclosporin].

1992 • 2 citations

Klinischer Krankheitsverlauf, histologische Befunde und therapeutische Probleme bei einem Patienten mit einem beidseitigen Ulcus rodens Mooren

1991 • 2 citations

[Cyclosporin and refractory idiopathic thrombocytopenic purpura. Possible therapeutic alternative].

1987 • 2 citations

Subcutaneous cyclosporin prevents the development of complete Freund's adjuvant-streptozotocin-induced diabetes in the rat.

1991 • 2 citations

Topical ketoconazole does not potentiate oral cyclosporin A in allergic contact dermatitis.

1992 • 2 citations

Inhibition of n-hexadecane-induced epidermal hyperplasia due to systemically administered ciclosporin.

1991 • 2 citations

Monitoring of erythropoiesis by serum transferrin receptor levels in a case of chronic lymphocytic leukaemia and pure red cell aplasia treated with ciclosporin.

1992 • 2 citations

[Membranoproliferative glomerulonephritis associated with Buckley's syndrome treated with cyclosporin].

1987 • 2 citations