Transcription Control Region Within the Protein-Coding Portion of Adenovirus E1A Genes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

A control region in the center of the 5S RNA gene directs specific initiation of transcription: II. The 3′ border of the region

1980 • 734 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

A control region in the center of the 5S RNA gene directs specific initiation of transcription: I. The 5′ border of the region

1980 • 578 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Simian virus 40 tandem repeated sequences as an element of the early promoter.

1981 • 462 citations

Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue

1978 • 408 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication

1981 • 304 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.

1980 • 287 citations

Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.

1978 • 282 citations

Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus

1982 • 276 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus

1982 • 253 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

DNA replication and the early to late transition in adenovirus infection

1980 • 248 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

Structure and in Vitro Transcription of Human Globin Genes

1980 • 231 citations

Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes

1980 • 217 citations

DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2.

1981 • 216 citations

Bisulfite Modification of Nucleic Acids and their Constituents

1976 • 214 citations

Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.

1980 • 195 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293)

1979 • 176 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

An expandable gene that encodes a Drosophila glue protein is not expressed in variants lacking remote upstream sequences

1982 • 165 citations

Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

1981 • 162 citations

The nucleotide sequence of the transforming HpaI-E fragment of adenovirus type 5 DNA

1978 • 157 citations

Cloning of a DNA fragment from the left-hand terminus of the adenovirus type 2 genome and its use in site-directed mutagenesis

1981 • 157 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite

1983 • 116 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

The yeast his3 promoter contains at least two distinct elements.

1982 • 102 citations

RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor.

1979 • 100 citations

Initiation of transcription by RNA polymerase II in permeable, SV40-infected or noninfected, CV1 cells; evidence for multiple promoters of SV40 late transcription

1981 • 84 citations

Analysis of the Sites of Integration of Viral DNA Sequences in Rat Cells Transformed by Adenovirus 2 or SV40

1980 • 71 citations

Expression of unselected adenovirus genes in human cells co-transformed with the HSV-1 tk gene and adenovirus 2 DNA

1980 • 66 citations

In vitro transcription of normal, mutant, and truncated mouse alpha-globin genes.

1980 • 55 citations

The molecular structure of the 9 S mRNA from early region 1A of adenovirus serotype 2

1983 • 52 citations

Mouse beta-globin and adenovirus-2 major late transcripts are initiated at the cap site in vitro.

1981 • 49 citations

Transcriptional control signals in the genome of bovine papillomavirus type 1

1983 • 48 citations

Autoregulation of Adenovirus Type 5 Early Gene Expression III. Transcription Studies in Isolated Nuclei

1979 • 45 citations

Far upstream initiation sites for adenovirus early region 1A transcription are utilized after the onset of viral DNA replication

1983 • 43 citations

Adenovirus terminal protein protects single stranded DNA from digestion by a cellular exonuclease

1980 • 37 citations

Mapping a eukaryotic promoter: a DNA sequence required for in vivo expression of adenovirus pre-early functions.

1981 • 31 citations