GSP1 and GSP2, Genetic Suppressors of the prp20-1 Mutant in Saccharomyces cerevisiae: GTP-Binding Proteins Involved in the Maintenance of Nuclear Organization

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Methods in Yeast Genetics

1988 • 4,905 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

[12] High-efficiency transformation of yeast by electroporation

1991 • 798 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

[20] In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast

1991 • 584 citations

Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication

1990 • 460 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

[29] Synthesis and sequence-specific proteolysis of hybrid proteins produced in Escherichia coli

1987 • 392 citations

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 • 376 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

1989 • 340 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

1991 • 281 citations

Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae.

1987 • 259 citations

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1991 • 231 citations

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

1991 • 195 citations

Cycloheximide resistance in yeast: the gene and its portein

1983 • 188 citations

Coupling M phase and S phase: Controls maintaining the dependence of mitosis on chromosome replication

1991 • 183 citations

Nucleotide binding and phosphorylation in microtubule assembly in vitro

1977 • 163 citations

Specific binding of [alpha-32P]GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C.

1987 • 157 citations

Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins.

1990 • 154 citations

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1990 • 152 citations

The subnuclear localization of tRNA ligase in yeast.

1987 • 133 citations

Purification and Characterization from Bovine Brain Cytosol of Two Gtpase-Activating Proteins Specific for smg p21, a GTP-binding Protein Having the Same Effector Domain as c-ras p21s

1989 • 120 citations

RCC1, a Regulator of Mitosis, Is Essential for DNA Replication

1992 • 106 citations

A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation.

1990 • 95 citations

Clues to the Function of Nm23 and Awd Proteins in Development, Signal Transduction, and Tumor Metastasis Provided by Studies of Dictyostelium discoideum

1990 • 82 citations

Mutational Analysis of CDC42Sc, a Saccharomyces cerevisiae Gene That Encodes a Putative GTP-Binding Protein Involved in the Control of Cell Polarity

1991 • 74 citations

A product of the prune locus of Drosophila is similar to mammalian GTPase-activating protein

1991 • 70 citations

Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation

1991 • 67 citations

Genetic and Physiological Control of Serine and Glycine Biosynthesis in Saccharomyces

1972 • 57 citations

Carbon source regulation of RAS1 expression in Saccharomyces cerevisiae and the phenotypes of ras2- cells.

1986 • 53 citations

Molecular Cloning and Characterization of a Novel Type of Regulatory Protein (GDI) for smg p25A, a ras p21-Like GTP-Binding Protein

1990 • 36 citations

GTP-binding proteins in rat liver nuclear envelopes.

1990 • 30 citations

Kinetic analysis of the binding of guanine nucleotide to bovine brain smg p25A

1989 • 28 citations

[50] Nucleolar-specific positive stains for optical and electron microscopy

1991 • 7 citations