Evidence that fibroblasts derive from epithelium during tissue fibrosis
Data up to Jan 2025
Total Citations Per Year
Abstract
References (54)
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 • 4,643 citations
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
2000 • 3,504 citations
Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell
2001 • 2,653 citations
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
1993 • 2,169 citations
Out of Eden: Stem Cells and Their Niches
2000 • 1,769 citations
An Overview of Epithelio-Mesenchymal Transformation
1995 • 1,505 citations
Stem cells find their niche
2001 • 1,428 citations
Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
1994 • 1,279 citations
The Evolving Concept of a Stem Cell
2001 • 1,058 citations
Identification and characterization of a fibroblast marker: FSP1.
1995 • 1,050 citations
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
1993 • 984 citations
Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
2001 • 921 citations
PCNA: structure, functions and interactions
1997 • 886 citations
Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities
2000 • 868 citations
Dissection of Key Events in Tubular Epithelial to Myofibroblast Transition and Its Implications in Renal Interstitial Fibrosis
2001 • 769 citations
Bone marrow contributes to renal parenchymal turnover and regeneration
2001 • 655 citations
Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor
1997 • 652 citations
Mouse gastrulation: the formation of a mammalian body plan
1997 • 595 citations
Marrow stromal stem cells
2000 • 592 citations
Mechanisms of Myofibroblast Activity and Phenotypic Modulation
1999 • 580 citations
Genetic programs of epithelial cell plasticity directed by transforming growth factor-β
2001 • 520 citations
Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro
1999 • 476 citations
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
2002 • 466 citations
Induction and regulation of epithelial–mesenchymal transitions
2000 • 434 citations
Transformations between epithelium and mesenchyme: Normal, pathological, and experimentally induced
1995 • 428 citations
Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats
1998 • 402 citations
Embryonic Lethality of Molecular Chaperone Hsp47 Knockout Mice Is Associated with Defects in Collagen Biosynthesis
2000 • 348 citations
Renal Fibrosis
2001 • 292 citations
Oncogenic Ras Downregulates Rac Activity, Which Leads to Increased Rho Activity and Epithelial–Mesenchymal Transition
2000 • 290 citations
Mesenchymal to Epithelial Conversion in Rat Metanephros Is Induced by LIF
1999 • 277 citations
Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice.
1995 • 239 citations
The Myofibroblast: An Assessment of Controversial Issues and a Definition Useful in Diagnosis and Research
2001 • 182 citations
Transdifferentiation and metaplasia — switching cell types
2001 • 178 citations
Progressive renal fibrosis in murine polycystic kidney disease: An immunohistochemical observation
2000 • 159 citations
Isolation of Primary and Immortalized CD34−Hematopoietic and Mesenchymal Stem Cells from Various Sources
2000 • 154 citations
Glomerulosclerosis is transmitted by bone marrow–derived mesangial cell progenitors
2001 • 128 citations
Impaired T Cell Function in RANTES-Deficient Mice
2002 • 122 citations
Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines
1992 • 114 citations
Clonal heterogeneity in fibroblast phenotype: Implications for the control of epithelial‐mesenchymal interactions
1987 • 103 citations
Conditional Abatement of Tissue Fibrosis Using Nucleoside Analogs to Selectively Corrupt DNA Replication in Transgenic Fibroblasts
2001 • 102 citations
Epithelial–Mesenchymal Transformation Is the Mechanism for Fusion of the Craniofacial Primordia Involved in Morphogenesis of the Chicken Lip
2000 • 97 citations
Myofibroblast and α1(III) collagen expression in experimental tubulointerstitial nephritis
1997 • 92 citations
Barrier cells: stromal regulation of hematopoiesis and blood cell release in normal and stressed murine bone marrow
1991 • 90 citations
Up-regulation of HSP47 in the mouse kidneys with unilateral ureteral obstruction
1998 • 84 citations
Rat Fibroblasts Cultured from Various Organs Exhibit Differences in α-Smooth Muscle Actin Expression, Cytoskeletal Pattern, and Adhesive Structure Organization
1998 • 75 citations
Fibroblast heterogeneity in physiological conditions and fibrotic disease
1999 • 74 citations
Heterogeneity in hormone responses and patterns of collagen synthesis in cloned dermal fibroblasts.
1990 • 73 citations
Spontaneous interstitial nephritis in kdkd mice. I. An experimental model of autoimmune renal disease.
1984 • 72 citations
Perspectives on the Morphology and Biology of CD34-Negative Stem Cells
2000 • 68 citations
Differentiation of canine bone marrow cells with hemopoietic characteristics from an adherent stromal cell precursor.
1995 • 55 citations
The Ballet of Morphogenesis
2002 • 51 citations
Subpopulations of rat lung fibroblasts with different amounts of type I and type III collagen mRNAs.
1990 • 37 citations
Fibroblast-like cells from embryonic chick cornea, heart, and skin are antigenically distinct
1979 • 34 citations
Comparative morphology of the marrow sac
2000 • 16 citations