Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3' noncoding region is mediated by a cotranslational mechanism.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

1988 • 1,884 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

1985 • 645 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo

1989 • 417 citations

Expression of the c-myb proto-oncogene during cellular proliferation

1986 • 360 citations

Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences

1989 • 347 citations

Translation is required for regulation of histone mRNA degradation

1987 • 345 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection.

1984 • 234 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse.

1985 • 193 citations

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences.

1987 • 182 citations

Complexity of the Early Genetic Response to Growth Factors in Mouse Fibroblasts

1988 • 159 citations

Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vectors.

1985 • 142 citations

U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation.

1992 • 135 citations

Absence of polyadenylate segment in globin messenger RNA accelerates its degradation in Xenopus oocytes.

1975 • 132 citations

Poly(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3' UTR of certain maternal mRNAs.

1990 • 128 citations

Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.

1991 • 127 citations

Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation.

1988 • 106 citations

c-myc RNA degradation in growing and differentiating cells: possible alternate pathways.

1989 • 98 citations

Effect of the tripartite leader on synthesis of a non-viral protein in an adenovirus 5 recombinant

1985 • 93 citations

Translation by the adenovirus tripartite leader: elements which determine independence from cap-binding protein complex

1990 • 88 citations

Premature Translation Termination Mediates Triosephosphate Isomerase mRNA Degradation

1988 • 82 citations

A 32-Kilodalton Protein Binds to AU-Rich Domains in the 3′ Untranslated Regions of Rapidly Degraded mRNAs

1991 • 81 citations

A change in the stability of globin mRNA during the induction of murine erythroleukemia cells

1978 • 79 citations

An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

1991 • 74 citations

Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.

1992 • 72 citations

Differential stability of c-myc mRNAS in a cell-free system.

1988 • 66 citations

Control of messenger RNA stability

1987 • 61 citations

Picornaviruses break the rules

1988 • 57 citations

Secondary Structure Analysis of Adenovirus Tripartite Leader

1989 • 38 citations