Poly(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3' UTR of certain maternal mRNAs.

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Do the poly(A) tail and 3′ untranslated region control mRNA translation?

1990 • 618 citations

Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element.

1989 • 412 citations

Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

1987 • 370 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1989 • 355 citations

Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU.

1989 • 332 citations

Polyadenylic Acid Segment in mRNA Becomes Shorter with Age

1973 • 317 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

The Role of the Poly(A) Sequence in Mammalian Messenger RN

1981 • 254 citations

Glucocorticoids enhance stability of human growth hormone mRNA.

1987 • 250 citations

Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.

1989 • 248 citations

Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA.

1987 • 211 citations

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

1983 • 190 citations

Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos

1989 • 185 citations

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences.

1987 • 182 citations

H4 histone messenger RNA decay in cell-free extracts initiates at or near the 3′ terminus and proceeds 3′ to 5′

1986 • 179 citations

Vasopressin mRNA in the Suprachiasmatic Nuclei: Daily Regulation of Polyadenylate Tail Length

1988 • 172 citations

In the beginning is the end: regulation of poly(A) addition and removal during early development

1990 • 153 citations

Poly(A) metabolism and polysomal recruitment of maternal mRNAs during early Xenopus development

1990 • 147 citations

The Vasopressin mRNA Poly(A) Tract is Unusually Long and Increases during Stimulation of Vasopressin Gene Expression in Vivo

1988 • 144 citations

Xfin: an embryonic gene encoding a multifingered protein in Xenopus.

1987 • 139 citations

Possible relationship of poly(A) shortening to mRNA turnover.

1975 • 110 citations

An analysis of the rate of metallothionein mRNA POLY(A)-shortening using RNA blot hybridization

1985 • 108 citations

Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation.

1988 • 106 citations

The vasopressin mRNA poly(A) tract is unusually long and increases during stimulation of vasopressin gene expression in vivo.

1988 • 98 citations

Metabolism of the polyadenylate sequence of nuclear RNA and messenger RNA in mammalian cells

1975 • 91 citations

Changes in RNA titers and polyadenylation during oogenesis and oocyte maturation in Xenopus laevis

1985 • 89 citations

Post-transcriptional processing of simian virus 40 late transcripts in injected frog oocytes

1983 • 88 citations

Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis.

1985 • 86 citations

Changes in the polyadenylation of specific stable RNA during the early development of Xenopus laevis

1988 • 85 citations

Widespread changes in the translation and adenylation of maternal messenger RNAs following fertilization of Spisula oocytes

1987 • 83 citations

Regulation of insulin mRNA abundance and adenylation: dependence on hormones and matrix substrata.

1986 • 76 citations

Stability of Maternal mRNA in Xenopus Embryos: Role of Transcription and Translation

1990 • 65 citations

A functionally redundant downstream sequence in SV40 late pre-mRNA is required for mRNA 3'-end formation and for assembly of a precleavage complex in vitro.

1988 • 64 citations

Glucocorticoids Enhance Stability of Human Growth Hormone mRNA

1987 • 62 citations

Stability of maternal mRNA in Xenopus embryos: role of transcription and translation.

1990 • 53 citations

Relatively Stable Population of c-myc RNA that Lacks Long Poly(A)

1987 • 44 citations

Poly(A) shortening of coregulated transcripts in Drosophila

1986 • 43 citations

Localized Maternal mRNAs in Xenopus laevis Eggs

1985 • 41 citations

Regulation of Insulin mRNA Abundance and Adenylation: Dependence on Hormones and Matrix Substrata

1986 • 18 citations

Accumulation and Behavior of mRNA During Oogenesis and Early Embryogenesis of Xenopus Laevis

1984 • 6 citations

Changes in the polyadenylation of specific stable RNA during the early development of Xenopus laevis.

1988 • 1 citations