Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Identification of an AUUUA-Specific Messenger RNA Binding Protein

1989 • 515 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.

1991 • 293 citations

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

1991 • 268 citations

Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases

1989 • 268 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene.

1985 • 207 citations

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

1991 • 184 citations

Determinants that contribute to cytoplasmic stability of human c-fos and beta-globin mRNAs are located at several sites in each mRNA.

1988 • 178 citations

Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions.

1990 • 163 citations

Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation

1989 • 129 citations

An A+U-Rich Element RNA-Binding Factor Regulates c-myc mRNA Stability In Vitro

1991 • 121 citations

Four novel U RNAs are encoded by a herpesvirus

1988 • 118 citations

The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype

1990 • 117 citations

Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization

1986 • 115 citations

A Region of the Herpesvirus saimiri Genome Required for Oncogenicity

1985 • 110 citations

Postinduction Turnoff of Beta-Interferon Gene Expression

1990 • 96 citations

A 32-Kilodalton Protein Binds to AU-Rich Domains in the 3′ Untranslated Regions of Rapidly Degraded mRNAs

1991 • 81 citations

An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

1991 • 74 citations

Poly(A) Shortening and Degradation of the 3′ A+U-Rich Sequences of Human c-myc mRNA in a Cell-Free System

1988 • 71 citations

Differential stability of c-myc mRNAS in a cell-free system.

1988 • 66 citations

Viral-encoded small RNAs in herpes virus saimiri induced tumors.

1986 • 59 citations

Postinduction repression of the beta-interferon gene is mediated through two positive regulatory domains.

1990 • 56 citations

Nucleotide sequence of HSUR 5 RNA from herpesvirus saimiri

1989 • 54 citations

Rapidc-mycmRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA

1991 • 43 citations

Determinants that Contribute to Cytoplasmic Stability of Human c-fos and β-Globin mRNAs are Located at Several Sites in Each mRNA

1988 • 42 citations

Herpesvirus saimiri U RNAs are expressed and assembled into ribonucleoprotein particles in the absence of other viral genes

1990 • 31 citations

Equal stabilities of normal beta globin and nontranslatable beta0 -39 thalassemic transcripts in cell-free extracts

1987 • 21 citations

Differential Stability of c-myc mRNAS in a Cell-Free System

1988 • 19 citations

Transformation by Herpesvirus Saimiri

1991 • 14 citations