Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Fusion between immunoglobulin‐secreting and nonsecreting myeloma cell lines

1976 • 729 citations

ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE

1961 • 576 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

[19] In Vitro packaging of λ and cosmid DNA

1979 • 537 citations

Interference of nonsense mutations with eukaryotic messenger RNA stability.

1979 • 454 citations

Rate of Somatic Mutation in Immunoglobulin Production by Mouse Myeloma Cells

1971 • 213 citations

Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences.

1982 • 150 citations

Somatic cell hybridization of mouse myeloma cells

1976 • 146 citations

Polarity and the Degradation of mRNA

1969 • 145 citations

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse.

1978 • 134 citations

Immunoglobulin chain loss in hybridoma lines.

1980 • 129 citations

Molecular analysis of spontaneous somatic mutants

1977 • 120 citations

Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain

1984 • 105 citations

Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class.

1980 • 101 citations

Mutations in Immunoglobulin-Producing Moose Myeloma Cells

1973 • 99 citations

Deletions in immunoglobulin mu chains.

1982 • 98 citations

Transcripts of the immunoglobulin C mu gene vary in structure and splicing during lymphoid development.

1980 • 89 citations

Molecular Basis of a Mutational Hot Spot in the Lysozyme Gene of Bacteriophage T4

1972 • 87 citations

Mutations affecting the structure and function of immunoglobulin M.

1982 • 69 citations

Roles of protein and carbohydrate in glycoprotein processing and secretion. Studies using mutants expressing altered IgM mu chains.

1981 • 42 citations

Hyper-labile messenger RNA in polar mutants of the tryptophan operon of Escherichia coli

1972 • 40 citations

Mutational events in mouse myeloma cells.

1981 • 37 citations

Mutant monoclonal antibodies with alterations in biological functions

1982 • 31 citations

Genetic Mechanism Accounting for Precise Immunoglobulin Domain Deletion in a Variant of MPC 11 Myeloma Cells

1979 • 23 citations

Mutations Affecting the Structure and Function of Immunoglobulin M

1982 • 22 citations

Nucleotide sequences of Immunoglobulin μ heavy chain deletion mutants

1983 • 14 citations