Isolation of RRM-type RNA-Binding Protein Genes and the Analysis of Their Relatedness by Using a Numerical Approach

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

The Neutral Theory of Molecular Evolution

1983 • 6,141 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

1984 • 776 citations

RNA recognition: towards identifying determinants of specificity

1991 • 739 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

ALTERNATIVE SPLICING IN THE CONTROL OF GENE EXPRESSION

1989 • 701 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

Sex in flies: the splice of life

1989 • 468 citations

Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins

1988 • 461 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence.

1987 • 393 citations

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression

1986 • 389 citations

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

1991 • 381 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1989 • 355 citations

The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages

1988 • 351 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

1988 • 302 citations

The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster

1988 • 284 citations

Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B" and their cognate RNAs

1990 • 283 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.

1991 • 196 citations

On/off regulation of gene expression at the level of splicing

1988 • 186 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

Structure of rodent helix-destabilizing protein revealed by cDNA cloning.

1986 • 173 citations

A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex

1989 • 162 citations

A Single Domain of Yeast Poly(A)-Binding Protein Is Necessary and Sufficient for RNA Binding and Cell Viability

1987 • 158 citations

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

1989 • 156 citations

Isolation and analysis of cDNA clones expressing human lupus La antigen.

1985 • 147 citations

Nomenclature for incompletely specified bases in nucleic acid sequences

1985 • 139 citations

Purification and domain structure of core hnRNP proteins A1 and A2 and their relationship to single-stranded DNA-binding proteins.

1986 • 123 citations

The nucleotde sequence of therhogene ofE. coliK-12

1983 • 93 citations

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

1988 • 90 citations

pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.

1987 • 89 citations

Nucleotide sequences involved in bacteriophage T4 gene 32 translational self-regulation.

1982 • 88 citations

Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA.

1985 • 85 citations

Amino acid sequence of the UP1 calf thymus helix-destabilizing protein and its homology to an analogous protein from mouse myeloma.

1985 • 82 citations

A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody.

1988 • 67 citations

Saccharomyces Cerevisiae SSB1 Protein and its Relationship to Nucleolar RNA-Binding Proteins

1987 • 50 citations

A cDNA clone of the hnRNP C proteins and its homology with the single-stranded DNA binding protein UP2

1986 • 48 citations

Single stranded DNA binding proteins derive from hnRNP proteins by proteolysis in mammalian cells

1985 • 42 citations

Nucleocytoplasmic RNA transport

1985 • 37 citations

Binding of mRNA by an oligopeptide containing an evolutionarily conserved sequence from RNA binding proteins

1989 • 12 citations