The Novel Primary Response Gene MyD118 and the Proto-Oncogenes myb, myc, and bcl-2 Modulate Transforming Growth Factor β1-induced Apoptosis of Myeloid Leukemia Cells

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

Genes specifically expressed at growth arrest of mammalian cells

1988 • 954 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas

1992 • 705 citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 • 698 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

1992 • 675 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

The MYC protein activates transcription of the alpha-prothymosin gene.

1991 • 589 citations

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.

1989 • 285 citations

MAMMALIAN GENES INDUCED BY RADIATION; Activation of Genes Associated with Growth Control

1992 • 284 citations

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells.

1991 • 279 citations

Expression of a Ryanodine Receptor-Ca ²⁺ Channel that is Regulated by TGF-β

1992 • 247 citations

Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues

1982 • 241 citations

The Molecular Control of Blood Cell Development

1987 • 234 citations

G₁/S Transition in Normal Human T-Lymphocytes Requires the Nuclear Protein Encoded by c-myb

1989 • 226 citations

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents.

1992 • 224 citations

Genotoxic‐Stress‐Response Genes and Growth‐Arrest Genes

1992 • 183 citations

Programmed cell death by bcl-2-dependent and independent mechanisms in B lymphoma cells.

1993 • 147 citations

Cell Death Studies Yield Cancer Clues

1993 • 120 citations

Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6

1990 • 88 citations

Origins of human cancer revisited

1990 • 53 citations

The role of transforming growth factor-beta in hematopoiesis. A review

1991 • 45 citations

Role of Transforming Growth Factor‐β1 in Regulation of Hematopoiesis^ab

1991 • 29 citations

Myeloblastic leukemia cells conditionally blocked by myc-estrogen receptor chimeric transgenes for terminal differentiation coupled to growth arrest and apoptosis

1993 • 28 citations

Control of JunB and Extracellular Matrix Protein Expression by Transforming Growth Factor-β1 Is Independent of Simian Virus 40 T Antigen-Sensitive Growth-Inhibitory Events

1991 • 14 citations