Simultaneous Expression of Two P-Glycoprotein Genes in Drug-Sensitive Chinese Hamster Ovary Cells

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1985 • 927 citations

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1985 • 843 citations

Isolation and expression of a complementary DNA that confers multidrug resistance

1986 • 808 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1986 • 680 citations

GENE AMPLIFICATION

1984 • 580 citations

Rapid duplication and loss of genes coding for the alpha chains of hemoglobin.

1980 • 531 citations

Molecular drive in multigene families: How biological novelties arise, spread and are assimilated

1986 • 478 citations

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

1986 • 410 citations

The molecular clock runs more slowly in man than in apes and monkeys

1987 • 383 citations

The current status and portability of our sequence handling software

1986 • 357 citations

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

1984 • 340 citations

Multidrug Resistance of DNA-Mediated Transformants is Linked to Transfer of the Human mdr1 Gene

1986 • 161 citations

Independent recombination events between the duplicated human α globin genes; implications for their concerted evolution

1984 • 157 citations

Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gets

1983 • 135 citations

Concerted evolution of the mouse immunoglobulin gamma chain genes.

1984 • 35 citations

Differential Expression of Three α-Tubulin Genes in Chinese Hamster Ovary Cells

1985 • 31 citations

Differential Amplification and Disproportionate Expression of Five Genes in Three Multidrug-Resistant Chinese Hamster Lung Cell Lines

1986 • 24 citations

Expression of Hamster P-Glycoprotein and Multidrug Resistance in Dna-Mediated Transformants of Mouse LTA Cells

1987 • 13 citations