Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gets

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Repetitive Sequences in Eukaryotic DNA and their Expression

1982 • 575 citations

DOUBLE MINUTES AND HOMOGENEOUSLY STAINING REGIONS: Gene Amplification in Mammalian Cells

1982 • 357 citations

Cold Spring Harbor Laboratory

1982 • 278 citations

Polynucleotide Sequence Relationships among Members of Enterobacteriaceae

1969 • 260 citations

An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments.

1982 • 197 citations

Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.

1982 • 184 citations

Possible Synthesis of Polyribonucleotides of Known Base-triplet Sequences

1965 • 180 citations

Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion

1981 • 171 citations

Hybridization of labeled RNA to DNA in agarose gels

1975 • 140 citations

Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.

1981 • 127 citations

A chicken middle-repetitive DNA sequence which shares homology with mammalian ubiquitous repeats

1981 • 105 citations

[6] Specific labeling of 3′ termini with T4 DNA polymerase

1980 • 102 citations

Loss of reiterated DNA sequences during serial passage of human diploid fibroblasts

1980 • 96 citations

Gene-amplification model of carcinogenesis.

1981 • 86 citations

Cloning of DNA from double minutes of Y1 mouse adrenocortical tumor cells: Evidence for gene amplification

1981 • 56 citations

General Method for Cloning Amplified DNA by Differential Screening with Genomic Probes

1982 • 47 citations

A restriction endonuclease cleavage map of mouse mitochondria I DNA

1977 • 36 citations

Gene amplification in methotrexate-resistant mouse cells

1981 • 34 citations

Relationship of Amplified Dihydrofolate Reductase Genes to Double Minute Chromosomes in Unstably Resistant Mouse Fibroblast Cell Lines

1981 • 34 citations

Gene evolution in the chicken β-globin cluster

1982 • 28 citations

cDNA sequence of a new chicken embryonic rho-globin.

1981 • 22 citations

Hemoglobin switching in sheep. Cloning and characterization of the beta A and beta-like embryonic globin genes from genomic DNA.

1980 • 20 citations

Cleavage sites of restriction endonucleases EcoRI, BamHI and HindIII on chicken embryo rDNA

1979 • 4 citations

Chicken ribosomal DNA: Gene frequency and purification by R-loop hybridization

1978 • 3 citations