Survivin and Bcl-2 Expression in Prostatic Adenocarcinomas

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Histologic grading of prostate cancer: A perspective

1992 • 1,059 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene

1992 • 724 citations

Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.

1998 • 720 citations

Expression of survivin and its relationship to loss of apoptosis in breast carcinomas

2000 • 561 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

A Novel Anti-Apoptosis Gene: Re-expression of Survivin Messenger RNA as a Prognosis Marker in Non–Small-Cell Lung Cancers

1999 • 498 citations

Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

1998 • 473 citations

Control of programmed cell death by the baculovirus genes p35 and iap.

1994 • 357 citations

Expression of the antiapoptosis gene, Survivin, predicts death from recurrent colorectal carcinoma

2000 • 327 citations

Expression of survivin in esophageal cancer: Correlation with the prognosis and response to chemotherapy

2001 • 323 citations

Expression of bcl-2 in fetal tissues suggests a role in morphogenesis.

1993 • 320 citations

Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis

2001 • 285 citations

bcl-2: Role in epithelial differentiation and oncogenesis

1996 • 272 citations

Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors

2001 • 256 citations

Elevated Levels of Apoptosis Regulator Proteins P53 and BCL-2 are Independent Prognostic Biomarkers in Surgically Treated Clinically Localized Prostate Cancer

1996 • 231 citations

Androgen-repressed phenotype in human prostate cancer

1996 • 229 citations

Human IAP-Like Protein Regulates Programmed Cell Death Downstream of Bcl-x_L and Cytochrome c

1998 • 216 citations

The new american joint committee on cancer and international union against cancer tnm classification of prostate cancer

1994 • 205 citations

Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts

1998 • 204 citations

Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients

2001 • 180 citations

p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients.

1996 • 157 citations

Prognostic value of bcl-2 oncoprotein expression in stage II colon carcinoma.

1995 • 127 citations

Neuroendocrine cells in human prostate over‐express the anti‐apoptosis protein survivin

2001 • 119 citations

Immunohistochemical evaluation of bcl-2 protein expression in gastric adenocarcinomas

1995 • 100 citations

Bcl-2 Oncoprotein Positivity and High MIB-1 (Ki-67) Proliferative Rate Are Independent Predictive Markers for Recurrence in Prostate Carcinoma

1998 • 98 citations

Regulation of apoptosis in prostate cancer.

2001 • 98 citations

Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti-apoptosis factors IAP (inhibitory of apoptosis proteins)

2002 • 90 citations

Zonal variation of apoptosis and proliferation in the normal prostate and in benign prostatic hyperplasia

1998 • 75 citations

Contribution of HER-2/neu oncogene expression to tumor grade and DNA content analysis in the prediction of prostatic carcinoma metastasis

1993 • 67 citations

Expression of bcl-2 oncoprotein in gastrointestinal and uterine carcinomas and their premalignant lesions

1997 • 63 citations

Absence of prognostic significance of bcl-2 immunopositivity in non-small cell lung cancer: Analysis of 427 cases

1997 • 54 citations

Can Expression of Apoptosis Genes, bcl-2 and bax, Predict Survival and Responsiveness to Chemotherapy in Node-Negative Breast Cancer Patients?

2001 • 47 citations

Prognostic markers for colorectal cancer: Expression of P53 and BCL2

1997 • 46 citations

Expression of the Apoptosis suppressing protein bcl-2 in prostatic adenocarcinoma is related to tumor malignancy

1997 • 45 citations

Bcl-2 Is a Useful Prognostic Marker in Dukes? B Colon Cancer

2001 • 40 citations

Bcl2, p53 and clinical outcome in a series of 138 operable breast cancer patients.

2000 • 35 citations

Bcl-2 Expression in Non-Small Cell Lung Cancers: Higher Frequency of Expression in Squamous Cell Carcinomas with Earlier pT Status

1999 • 30 citations

Prognostic factors in prostate cancer.

1997 • 21 citations

Increased bcl-2 protein levels in prostatic adenocarcinomas are not associated with rearrangements in the 2.8 kb major breakpoint region or with p53 protein accumulation.

1996 • 19 citations

CD40 and Bcl2 expression in squamous cell carcinoma of the lung: correlation with apoptosis, survival, and other clinicopathological factors

1999 • 12 citations