Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

1994 • 1,145 citations

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1993 • 1,049 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1995 • 976 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Prevention of Programmed Cell Death in Caenorhabditis elegans by Human bcl-2

1992 • 608 citations

The CARD domain: a new apoptotic signalling motif

1997 • 532 citations

An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs

1994 • 530 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus

1993 • 284 citations

Inhibition of Reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs)

1997 • 210 citations

Inhibition of interleukin 1β-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP

1996 • 105 citations

Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line

1997 • 45 citations