Multiple Mechanisms Provide Rapid and Stringent Glucose Repression of GAL Gene Expression in Saccharomyces cerevisiae

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

A Yeast Gene That Is Essential for Release from Glucose Repression Encodes a Protein Kinase

1986 • 688 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

GENES AFFECTING THE REGULATION OF SUC2 GENE EXPRESSION BY GLUCOSE REPRESSION IN SACCHAROMYCES CEREVISIAE

1984 • 567 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA.

1983 • 415 citations

Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response.

1991 • 400 citations

The organization and transcription of the galactose gene cluster of Saccharomyces

1981 • 350 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

Cooperative DNA binding of the yeast transcriptional activator GAL4.

1988 • 227 citations

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1987 • 226 citations

Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression.

1991 • 211 citations

Induction of Galactokinase in Saccharomyces cerevisiae : Kinetics of Induction and Glucose Effects

1972 • 203 citations

A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription.

1986 • 162 citations

GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae

1986 • 127 citations

YeastSKO1gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription

1992 • 113 citations

Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator.

1989 • 106 citations

Catabolite inactivation of the galactose uptake system in yeast.

1977 • 100 citations

Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases.

1988 • 94 citations

Isolation and expression analysis of two yeast regulatory genes involved in the derepression of glucose-repressible enzymes

1987 • 78 citations

Extragenic suppressors of yeast glucose derepression mutants leading to constitutive synthesis of several glucose-repressible enzymes

1991 • 74 citations

GAL4 is phosphorylated as a consequence of transcriptional activation.

1991 • 71 citations

Genetic and molecular characterization of GAL83: its interaction and similarities with other genes involved in glucose repression in Saccharomyces cerevisiae.

1993 • 61 citations

GAL4 is regulated by a glucose-responsive functional domain.

1993 • 61 citations

Multiple mechanisms mediate glucose repression of the yeast GAL1 gene.

1992 • 54 citations

Analysis of URSG-mediated glucose repression of the GAL1 promoter of Saccharomyces cerevisiae.

1992 • 48 citations

Role of cyclic-AMP-dependent protein kinase in catabolite inactivation of the glucose and galactose transporters in Saccharomyces cerevisiae

1989 • 38 citations