Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Tumor suppressor genes

1991 • 775 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

A Yeast Gene That Is Essential for Release from Glucose Repression Encodes a Protein Kinase

1986 • 688 citations

A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae

1987 • 676 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 310 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

A SUPPRESSOR OF snf1 MUTATIONS CAUSES CONSTITUTIVE HIGH-LEVEL INVERTASE SYNTHESIS IN YEAST

1984 • 228 citations

Cooperative DNA binding of the yeast transcriptional activator GAL4.

1988 • 227 citations

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

1990 • 207 citations

Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae.

1990 • 178 citations

Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast.

1982 • 176 citations

Regulation of sugar utilization in Saccharomyces species

1987 • 172 citations

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.

1988 • 145 citations

Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes.

1984 • 129 citations

GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae

1986 • 127 citations

In vivo DNA-binding properties of a yeast transcription activator protein.

1987 • 112 citations

Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator.

1989 • 106 citations

Catabolite inactivation of the galactose uptake system in yeast.

1977 • 100 citations

Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases.

1988 • 94 citations

Use of lacZ Fusions to Delimit Regulatory Elements of the Inducible Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 90 citations

Isolation and characterization of a pleiotropic glucose repression resistant mutant of Saccharomyces cerevisiae

1984 • 88 citations

Characterization of TUP1, a Mediator of Glucose Repression in Saccharomyces cerevisiae

1990 • 63 citations

Two Systems of Glucose Repression of the GAL1 Promoter in Saccharomyces cerevisiae

1990 • 52 citations

Controlled transcription of the yeast regulatory gene GAL80

1985 • 50 citations

GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae

1988 • 43 citations

Disruption of Regulatory Gene GAL80 in Saccharomyces cerevisiae: Effects on Carbon-Controlled Regulation of the Galactose/Melibiose Pathway Genes

1984 • 43 citations

In Vivo DNA-Binding Properties of a Yeast Transcription Activator Protein

1987 • 38 citations

Yeast Regulatory Gene GAL3: Carbon Regulation; UAS_Gal Elements in Common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; Encoded Protein Strikingly Similar to Yeast and Escherichia coli Galactokinases

1988 • 26 citations