Expression of novel isoforms of carnitine palmitoyltransferase I (CPT-1) generated by alternative splicing of the CPT-Iβ gene

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis

1997 • 1,573 citations

Interpreting cDNA sequences: Some insights from studies on translation

1996 • 785 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

CARNITINE

1988 • 610 citations

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

1978 • 586 citations

IMPORT OF PROTEINS INTO MITOCHONDRIA

1991 • 583 citations

Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.

1993 • 392 citations

Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.

1987 • 242 citations

Alternative mRNA Splicing

1992 • 219 citations

Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase I. Direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function.

1993 • 219 citations

Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. I. Use of inhibitors.

1987 • 183 citations

Mitochondrial Carnitine Palmitoyltransferase I Isoform Switching in the Developing Rat Heart

1995 • 168 citations

Expression of a cDNA Isolated from Rat Brown Adipose Tissue and Heart Identifies the Product as the Muscle Isoform of Carnitine Palmitoyltransferase I (M-CPT I)

1996 • 155 citations

Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. II. Use of detergents and antibodies.

1987 • 149 citations

Cloning, sequencing, and expression of a cDNA encoding rat liver mitochondrial carnitine palmitoyltransferase II.

1990 • 144 citations

Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.

1995 • 140 citations

Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane

1997 • 133 citations

Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I. The minor component is identical to the liver enzyme.

1994 • 126 citations

High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone

1995 • 126 citations

cDNA cloning, sequence analysis, and chromosomal localization of the gene for human carnitine palmitoyltransferase.

1991 • 124 citations

Use of a selective inhibitor of liver carnitine palmitoyltransferase I (CPT I) allows quantification of its contribution to total CPT I activity in rat heart. Evidence that the dominant cardiac CPT I isoform is identical to the skeletal muscle enzyme

1994 • 121 citations

Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I

1996 • 120 citations

Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I

1995 • 100 citations

The ethanol-inducible YAT1 gene from yeast encodes a presumptive mitochondrial outer carnitine acetyltransferase.

1993 • 83 citations

Catalytically important domains of rat carnitine palmitoyltransferase II as determined by site-directed mutagenesis and chemical modification. Evidence for a critical histidine residue.

1994 • 67 citations

Structural features of the gene encoding human muscle type carnitine palmitoyltransferase I¹

1997 • 63 citations

Functional Characterization of Mitochondrial Carnitine Palmitoyltransferases I and II Expressed in the Yeast Pichia pastoris^,

1997 • 59 citations

Expression of a cDNA for rat liver carnitine palmitoyltransferase I in yeast establishes that catalytic activity and malonyl-CoA sensitivity reside in a single polypeptide

1994 • 49 citations

Cloning and sequencing of a cDNA encoding Saccharomyces cerevisiae carnitine acetyltransferase. Use of the cDNA in gene disruption studies.

1993 • 48 citations

Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes

1990 • 48 citations

Inhibitors of mitochondrial carnitine palmitoyltransferase I limit the action of proteases on the enzyme. Isolation and partial amino acid analysis of a truncated form of the rat liver isozyme.

1993 • 47 citations

Change in Expression of Heart Carnitine Palmitoyltransferase I Isoforms with Electrical Stimulation of Cultured Rat Neonatal Cardiac Myocytes

1996 • 46 citations

Characterization of the malonyl-CoA-sensitive carnitine palmitoyltransferase (CPTo) of a rat heart mitochondrial particle. Evidence that the catalytic unit is CPTi.

1994 • 43 citations

Yonetani-Theorell analysis of hepatic carnitine palmitoyltransferase-I inhibition indicates two distinct inhibitory binding sites.

1994 • 42 citations

Cloning, sequencing, and regulation of rat liver carnitine octanoyltransferase: transcriptional stimulation of the enzyme during peroxisome proliferation

1988 • 41 citations

Mature carnitine palmitoyltransferase I retains the N‐terminus of the nascent protein in rat liver

1993 • 36 citations

Kinetic Properties of Carnitine Palmitoyltransferase I in Cultured Neonatal Rat Cardiac Myocytes

1994 • 24 citations