Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras-related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain.

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1991 • 785 citations

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1992 • 684 citations

The PH domain: a common piece in the structural pathcwork of signalling proteins

1993 • 536 citations

Molecular Cloning of Two Types of GAP Complementary DNA from Human Placenta

1988 • 492 citations

Bcr encodes a GTPase-activating protein for p21rac

1991 • 474 citations

Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator

1992 • 430 citations

Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus

1992 • 343 citations

Differential regulation of rasGAP and neurofibromatosis gene product activities

1991 • 338 citations

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1992 • 324 citations

Association between GTPase activators for Rho and Ras families

1992 • 322 citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1993 • 319 citations

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1991 • 273 citations

Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

1990 • 174 citations

Gap Domains Responsible for Ras P21-Dependent Inhibition of Muscarinic Atrial K ⁺ Channel Currents

1992 • 154 citations

The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation

1992 • 129 citations

Differential expression of two types of the neurofibromatosis type 1 (NF1) gene transcripts related to neuronal differentiation.

1991 • 119 citations

Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides.

1993 • 115 citations

Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes.

1993 • 95 citations

Different structural organization of Ras and Rho effector domains.

1993 • 83 citations

Diversity and versatility of GTPase activating proteins for the p21rho subfamily of ras G proteins detected by a novel overlay assay.

1992 • 76 citations

Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain

1993 • 70 citations

The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.

1993 • 69 citations

The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid.

1991 • 69 citations

The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1

1992 • 54 citations

Characterization of bcr gene products in hematopoietic cells.

1989 • 40 citations

Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence

1992 • 33 citations

Chronic Manganese Treatment of Rats Alters Synaptosomal Uptake of Dopamine and the Behavioural Response to Amphetamine Administration

1982 • 20 citations