Engagement of interleukin-7 receptor stimulates tyrosine phosphorylation, phosphoinositide turnover, and clonal proliferation of human T-lineage acute lymphoblastic leukemia cells

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

1980 • 1,668 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1989 • 978 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

1990 • 614 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Differentiation-Linked Leukemogenesis in Lymphocytes

1986 • 359 citations

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

1989 • 288 citations

Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells.

1989 • 230 citations

Acute lymphoblastic leukemia: recent advances in biology and therapy [see comments]

1989 • 203 citations

Regulation of human T cell proliferation by IL-7.

1990 • 183 citations

Effect of IL-7 on the growth of fetal thymocytes in culture.

1989 • 179 citations

Interleukin 7 enhances cytolytic T lymphocyte generation and induces lymphokine-activated killer cells from human peripheral blood.

1990 • 160 citations

Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia

1990 • 158 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

Tyrosine Phosphorylation of Phospholipase C-II in Vitro by the Epidermal Growth Factor Receptor

1989 • 145 citations

Interleukin 7: effects on early events in lymphopoiesis

1989 • 140 citations

IL-7 promotes thymocyte proliferation and maintains immunocompetent thymocytes bearing alpha beta or gamma delta T-cell receptors in vitro: synergism with IL-2.

1989 • 119 citations

Autologous bone marrow transplantation in high-risk remission T-lineage acute lymphoblastic leukemia using immunotoxins plus 4- hydroperoxycyclophosphamide for marrow purging

1990 • 88 citations

Marrow purging in autologous bone marrow transplantation for T-lineage acute lymphoblastic leukemia: efficacy of ex vivo treatment with immunotoxins and 4-hydroperoxycyclophosphamide against fresh leukemic marrow progenitor cells

1987 • 82 citations

In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B- and pro-T-lymphocyte clones and fetal thymocyte clones.

1989 • 80 citations

Two-dimensional Analysis of Interleukin 2-Regulated Tyrosine Kinase Activation Mediated by the p70-75 β Subunit of the Interleukin 2 Receptor

1989 • 79 citations

Interleukin-3 stimulates the tyrosine phosphorylation of the 140-kilodalton interleukin-3 receptor

1989 • 74 citations

Effects of recombinant human IL-7 on blast cell proliferation in acute lymphoblastic leukemia.

1990 • 49 citations

Antigen-independent regulation of cytoplasmic calcium in B cells with a 12-kDa B-cell growth factor and anti-CD19.

1988 • 49 citations

Use of colony assays and anti-T cell immunotoxins to elucidate the immunobiologic features of leukemic progenitor cells in T-lineage acute lymphoblastic leukemia.

1988 • 41 citations

The 75,000-Dalton Interleukin-2 Receptor Transmits a Signal for the Activation of a Tyrosine Protein Kinase

1989 • 32 citations

Accessory receptors regulate coupling of the T-cell receptor complex to tyrosine kinase activation and mobilization of cytoplasmic calcium in T- lineage acute lymphoblastic leukemia

1991 • 19 citations

Platelet-derived Growth Factor Induces Phosphorylation of a 64-kDa Nuclear Protein

1989 • 11 citations

Identification of an Adipocyte Protein that Binds to Calmodulin in the Absence of Ca2+ and is Phosphorylated in Response to Insulin and Tumor-Promoting Phorbol Esters

1989 • 10 citations