Interleukin-3 stimulates the tyrosine phosphorylation of the 140-kilodalton interleukin-3 receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

1983 • 559 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity.

1983 • 465 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C

1985 • 255 citations

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

1986 • 238 citations

Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines.

1988 • 222 citations

Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: Similarity in size, hydrophobicity, and charge

1982 • 207 citations

Characterization and partial purification of a haemopoietic cell growth factor in WEHI-3 cell conditioned medium

1983 • 192 citations

Phenotypic characteristics of cell lines requiring interleukin 3 for growth.

1982 • 158 citations

Interleukin 3: Possible Roles in the Regulation of Lymphocyte Differentiation and Growth

1982 • 157 citations

Evidence for specific receptors for interleukin 3 on lymphokine-dependent cell lines established from long-term bone marrow cultures.

1984 • 155 citations

Stimulation of hematopoiesis in patients with bone marrow failure and in patients with malignancy by recombinant human granulocyte-macrophage colony-stimulating factor

1988 • 132 citations

Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi-factor-dependent myeloid cell lines.

1987 • 129 citations

Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 alpha).

1986 • 122 citations

Stimulation of factor-dependent myeloid cell lines with interleukin 3 induces tyrosine phosphorylation of several cellular substrates.

1988 • 117 citations

Identification of distinct receptors for two hemopoietic growth factors (granulocyte colony-stimulating factor and multipotential colony-stimulating factor) by chemical cross-linking.

1986 • 113 citations

Interleukin 3 stimulates proliferation via protein kinase C activation without increasing inositol lipid turnover.

1988 • 108 citations

Interleukin 3 binds to a 140-kDa phosphotyrosine-containing cell surface protein.

1988 • 104 citations

Identification of the interleukin-3 receptor using an iodinatable, cleavable, photoreactive cross-linking agent.

1986 • 86 citations

Removal of dodecyl sulfate from protein solution

1988 • 82 citations

Interleukin-3, GM-CSF, and TPA induce distinct phosphorylation events in an interleukin 3-dependent multipotential cell line

1989 • 78 citations

Affinity isolation of the interleukin-3 surface receptor

1986 • 57 citations

Identification of a signal-transduction pathway shared by haematopoietic growth factors with diverse biological specificity

1987 • 47 citations

Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis

1988 • 42 citations

A preliminary report: preparations containing Interleukin-3 (IL-3) promote proliferation of multipotential stem cells (CFUs) in the mouse.

1983 • 40 citations

Interleukin-3 down-regulates its own receptor

1989 • 40 citations

Cloned lines on interleukin 2 producer human T lymphocytes.

1982 • 33 citations

Molecularly cloned and expressed murine T-cell gene product is biologically similar to interleukin-3.

1985 • 22 citations

Fluorescein and tetramethyl rhodamine as haptens in enzyme immunohistochemistry

1986 • 16 citations

Monoclonal antibody C3.1 is a platelet derived growth factor (PDGF) antagonist

1987 • 4 citations