Activation of Peripheral Blood T Cells by Interaction and Migration Through Endothelium: Role of Lymphocyte Function Antigen-1/Intercellular Adhesion Molecule-1 and Interleukin-15

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

1994 • 1,423 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Preferential Migration of Activated CD4 ⁺ and CD8 ⁺ T Cells in Response to MIP-1α and MIP-1β

1993 • 737 citations

Lymphocyte interactions with endothelial cells

1992 • 689 citations

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.

1994 • 541 citations

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

1997 • 513 citations

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1996 • 492 citations

IL-15: A Pleiotropic Cytokine with Diverse Receptor/Signaling Pathways Whose Expression Is Controlled at Multiple Levels

1996 • 459 citations

Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes.

1992 • 395 citations

Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes.

1991 • 388 citations

Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin.

1992 • 309 citations

Chemoattraction of human blood T lymphocytes by interleukin-15.

1995 • 303 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers.

1986 • 289 citations

Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes.

1988 • 283 citations

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway.

1995 • 265 citations

Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis.

1988 • 249 citations

Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis

1988 • 248 citations

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo.

1998 • 234 citations

Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopes

1991 • 231 citations

Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis

1997 • 219 citations

Upregulated expression and function of VLA-4 fibronectin receptors on human activated T cells in rheumatoid arthritis.

1991 • 203 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Activation of naive and memory T cells by interleukin-15

1996 • 183 citations

Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms.

1997 • 182 citations

Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitis

1998 • 155 citations

Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia.

1993 • 150 citations

Activation of naive and memory T cells by interleukin-15

1996 • 141 citations

Differential Distribution of Intercellular Adhesion Molecules (ICAM–1, ICAM–2, and ICAM–3) and THE MS–1 Antigen in Normal and Diseased Human Synovia

1994 • 131 citations

Phenotypic characterization of CD4+ T cells that exhibit a transendothelial migratory capacity.

1995 • 129 citations

An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells.

1991 • 122 citations

Evidence for recent as well as long term activation of T cells migrating through endothelial cell monolayers in vitro.

1992 • 118 citations

Identification of subsets of human T cells capable of enhanced transendothelial migration.

1992 • 98 citations

ICAM-3 regulates lymphocyte morphology and integrin-mediated T cell interaction with endothelial cell and extracellular matrix ligands.

1994 • 86 citations

Evidence for the continuous recruitment and activation of T cells into the joints of patients with rheumatoid arthritis

1994 • 76 citations

The intrinsic migratory capacity of memory T cells contributes to their accumulation in rheumatoid synovium

1992 • 66 citations

Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis.

1993 • 55 citations

Interleukin‐15 induces adhesion receptor redistribution in T lymphocytes

1996 • 54 citations

Characterization and regulation of CD69 expression on rheumatoid arthritis synovial fluid T cells.

1995 • 37 citations

Phenotypic characterization of CD4-/alpha beta TCR+ and gamma delta TCR+ T cells with a transendothelial migratory capacity.

1994 • 37 citations

High avidity state of leukocyte function-associated antigen-1 on rheumatoid synovial fluid T lymphocytes.

1995 • 29 citations

Deleted Work

1955 • 0 citations