Different molecular consequences of the 1;19 chromosomal translocation in childhood B-cell precursor acute lymphoblastic leukemia

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all

1990 • 726 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif

1990 • 478 citations

Four-Agent Induction and Intensive Asparaginase Therapy for Treatment of Childhood Acute Lymphoblastic Leukemia

1986 • 432 citations

Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy

1991 • 387 citations

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia

1984 • 365 citations

lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

1989 • 358 citations

Leukemia and the disruption of normal hematopoiesis

1991 • 357 citations

Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia

1990 • 354 citations

B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation.

1984 • 324 citations

Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study

1990 • 264 citations

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.

1991 • 237 citations

The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias

1991 • 218 citations

Pre-B cell leukemia associated with chromosome translocation 1;19

1984 • 203 citations

A direct bone marrow chromosome technique for acute lymphoblastic leukemia

1984 • 193 citations

Cytogenetics of pre-B-cell acute lymphoblastic leukemia with emphasis on prognostic implications of the t(1;19).

1990 • 188 citations

The Gene for Enhancer Binding Proteins E12/E47 Lies at the t(1;19) Breakpoint in Acute Leukemias

1989 • 159 citations

Consistent involvement of the bcr gene by 9;22 breakpoints in pediatric acute leukemias

1991 • 107 citations

Lack of association between abnormalities of the chromosome 9 short arm and either "lymphomatous" features or T cell phenotype in childhood acute lymphocytic leukemia

1987 • 79 citations

High‐dose methotrexate improves clinical outcome in children with acute lymphoblastic leukemia: St. Jude total therapy study X

1988 • 68 citations

Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia.

1989 • 67 citations

Molecular analysis of the t(1;19) breakpoint cluster region in pre‐b cell acute lymphoblastic leukemias

1990 • 56 citations

Transfer and expression of the gene encoding a human myeloid membrane antigen (gp150).

1985 • 48 citations

The human VAV proto-oncogene maps to chromosome region 19p12?19p13.2

1990 • 21 citations