Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy

Multiple-Drug Resistance in Human Cancer

1987 • 703 citations

Rationale for the use of alternating non-cross-resistant chemotherapy.

1982 • 545 citations

Secondary Acute Myeloid Leukemia in Children Treated for Acute Lymphoid Leukemia

1989 • 457 citations

Four-Agent Induction and Intensive Asparaginase Therapy for Treatment of Childhood Acute Lymphoblastic Leukemia

1986 • 432 citations

The Effectiveness of Combinations of Antileukemic Agents in Inducing and Maintaining Remission in Children with Acute Leukemia

1965 • 314 citations

Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study

1990 • 264 citations

Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study

1990 • 228 citations

A direct bone marrow chromosome technique for acute lymphoblastic leukemia

1984 • 193 citations

Results and Significance of Six Randomized Trials in Four Consecutive ALL-BFM Studies

1990 • 188 citations

Initial congestive heart failure, six to ten years after doxorubicin chemotherapy for childhood cancer

1990 • 170 citations

Prognostic factors in childhood T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 126 citations

Clinical pharmacology of intrathecal methotrexate. II. An improved dosage regimen derived from age-related pharmacokinetics.

1977 • 114 citations

Correlation of karyotype and immunophenotype in childhood acute lymphoblastic leukemia.

1988 • 105 citations

Prognostic factors in childhood T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 95 citations

Age at diagnosis in childhood acute lymphoblastic leukemia

1986 • 84 citations

Prognostic importance of the pre-B-cell immunophenotype and other presenting features in B-lineage childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study

1989 • 77 citations

Clinical and biologic features predict poor prognosis in acute lymphoid leukemias in children and adolescents: A pediatric oncology group review

1986 • 76 citations

High‐dose methotrexate improves clinical outcome in children with acute lymphoblastic leukemia: St. Jude total therapy study X

1988 • 68 citations

Molecular heterogeneity in acute leukemia lineage switch

1989 • 67 citations

Prognostic importance of the pre-B-cell immunophenotype and other presenting features in B-lineage childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study

1989 • 55 citations

Teniposide plus cytarabine improves outcome in childhood acute lymphoblastic leukemia presenting with a leukocyte count greater than or equal to 100 x 10(9)/L.

1987 • 45 citations

Clinical pharmacodynamics of anticancer drugs: a basis for extending the concept of dose-intensity

1988 • 43 citations

Intermediate dose methotrexate in childhood acute lymphocytic leukemia

1984 • 41 citations

Variation by race in presenting clinical and biologic features of childhood acute lymphoblastic leukaemia: Implications for treatment outcome

1985 • 40 citations

The Cytogenetics of Childhood Leukemia: Clinical and Biologic Implications

1988 • 25 citations

Early results of intensified remission induction chemotherapy for childhood acute lymphocytic leukemia

1986 • 21 citations

Limiting Toxicities During Intensified Remission Induction Chemotherapy for Childhood Acute Lymphocytic Leukemia

1987 • 8 citations

Rapidly rotating combination chemotherapy in childhood acute lymphoblastic leukemia: preliminary results of a randomized comparison with conventional treatment.

1988 • 8 citations