Cytoplasmic Ca2+ oscillations evoked by receptor stimulation, G-protein activation, internal application of inositol trisphosphate or Ca2+: simultaneous microfluorimetry and Ca2+ dependent Cl- current recording in single pancreatic acinar cells.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Physiology of the Gastrointestinal Tract.

1987 • 1,948 citations

Calcium release from the sarcoplasmic reticulum

1977 • 1,580 citations

Single channel recording

1984 • 981 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

Calcium Induced Release of Calcium from the Sarcoplasmic Reticulum of Skinned Skeletal Muscle Fibres

1970 • 802 citations

Cytosolic calcium oscillators

1988 • 690 citations

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

1975 • 684 citations

Calcium-activated potassium channels and their role in secretion

1984 • 659 citations

Fluorescent Probes of Cell Signaling

1989 • 649 citations

Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels

1987 • 529 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Pancreozymin, a stimulant of the secretion of pancreatic enzymes in extracts of the small intestine

1943 • 441 citations

Calcium channels: Molecular pharmacology, structure and regulation

1988 • 382 citations

The Ca signal from fura‐2 loaded mast cells depends strongly on the method of dye‐loading

1985 • 356 citations

Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration

1989 • 338 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.

1988 • 294 citations

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

1989 • 259 citations

Localization and heterogeneity of agonist-induced changes in cytosolic calcium concentration in single bovine adrenal chromaffin cells from video imaging of fura-2.

1989 • 236 citations

Single-channel currents in isolated patches of plasma membrane from basal surface of pancreatic acini

1982 • 206 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

Relationship between secretagogue-induced Ca2+ release and inositol polyphosphate production in permeabilized pancreatic acinar cells.

1985 • 184 citations

P2-Purinergic Agonists Stimulate Phosphodiesteratic Cleavage of Phosphatidylcholine in Endothelial Cells

1989 • 180 citations

Cholecystokinin activation of single-channel currents is mediated by internal messenger in pancreatic acinar cells

1982 • 177 citations

Inositol trisphosphate-induced membrane potential oscillations in Xenopus oocytes.

1988 • 160 citations

Electrophysiology of Pancreatic and Salivary Acinar Cells

1988 • 140 citations

Oscillations of cytosolic calcium in single pancreatic acinar cells stimulated by acetylcholine

1988 • 132 citations

Characterization of inositol 1,4,5-trisphosphate-sensitive (IsCaP) and-insensitive (IisCaP) nonmitochondrial Ca2+ pools in rat pancreatic acinar cells

1989 • 129 citations

Multiple Sources of 1,2-Diacylglycerol in Isolated Rat Pancreatic Acini Stimulated by Cholecystokinin

1989 • 120 citations

Physiological localization of an agonist-sensitive pool of Ca2+ in parotid acinar cells.

1989 • 102 citations

Pancreatic acinar cells: ionic dependence of the membrane potential and acetylcholine‐induced depolarization

1973 • 92 citations

Inositol 1,3,4,5‐tetrakisphosphate and inositol 1,4,5‐trisphosphate act by different mechanisms when controlling C²⁺ in mouse lacrimal acinar cells

1989 • 89 citations

Calcium Transport Pathways of Pancreatic Acinar Cells

1989 • 89 citations

Potentiation of muscarinic and alpha-adrenergic responses by an analogue of guanosine 5'-triphosphate.

1986 • 83 citations

Pancreatic acinar cells: membrane potential and resistance change evoked by acetylcholine

1974 • 76 citations

Electrogenic properties of the sodium-alanine cotransporter in pancreatic acinar cells: I. Tight-seal whole-cell recordings

1986 • 73 citations

Modulation of intracellular free Ca2+ concentration by IP3-sensitive and IP3-insensitive nonmitochondrial Ca2+ pools

1989 • 71 citations

Acetylcholine and cholecystokinin receptors functionally couple by different G‐proteins to phospholipase C in pancreatic acinar cells

1988 • 62 citations

Messenger role of calcium in function of pancreatic acinar cells

1980 • 59 citations

Vasopressin directly closes ATP-sensitive potassium channels evoking membrane depolarization and an increase in the free intracellular Ca2+ concentration in insulin-secreting cells.

1989 • 57 citations

Calcium and secretagogues-induced conductances in rat exocrine pancreas

1988 • 49 citations

Measurement of cytosolic free Ca²⁺ in individual pancreatic acini

1988 • 47 citations

Patch-clamp study of single-channel and whole-cell K+ currents in guinea pig pancreatic acinar cells

1988 • 45 citations

Pancreatic acinar cells: effect of acetylcholine, pancreozymin, gastrin and secretin on membrane potential and resistance in vivo and in vitro.

1975 • 44 citations

Caffeine slows turn-off of calcium release in voltage clamped skeletal muscle fibers

1989 • 43 citations

Mouse pancreatic acinar cells: the anion selectivity of the acetylcholine‐opened chloride pathway.

1980 • 35 citations

Thyrotropin-releasing hormone-induced rise in cytosolic calcium and activation of outward K+ current monitored simultaneously in individual GH3B6 pituitary cells.

1988 • 27 citations

Effects of intracellular EGTA injection on stimulant-evoked membrane potential and resistance changes in pancreatic acinar cells

1980 • 17 citations

Mechanism of Action of Pancreozymin and Acetylcholine on Pancreatic Acinar Cells

1973 • 17 citations