Relationship between secretagogue-induced Ca2+ release and inositol polyphosphate production in permeabilized pancreatic acinar cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

1983 • 1,104 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

ENZYME SECRETION AND THE INCORPORATION OF P32 INTO PHOSPHOLIPIDES OF PANCREAS SLICES

1953 • 757 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

The second messenger linking receptor activation to internal Ca release in liver

1984 • 557 citations

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones

1983 • 547 citations

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

1982 • 541 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate

1984 • 410 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary artery

1984 • 389 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

Phosphatidyldmositol hydrolysis: A multifunctional transducing mechanism

1981 • 341 citations

Rapid decrease of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets.

1982 • 323 citations

Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreas

1984 • 305 citations

Inositol trisphosphates in carbachol-stimulated rat parotid glands

1984 • 296 citations

Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone action.

1983 • 292 citations

Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes.

1983 • 232 citations

Breakdown of polyphosphoinositides and not phosphatidylinositol accounts for muscarinic agonist-stimulated inositol phospholipid metabolism in rat parotid glands

1983 • 226 citations

Hormone-stimulated metabolism of inositol lipids and its relationship to hepatic receptor function

1981 • 205 citations

Phosphatidylinositol-4,5-bisphosphate phosphodiesterase and phosphomonoesterase activities of rat brain. Some properties and possible control mechanisms

1984 • 194 citations

Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils

1983 • 188 citations

Receptor-mediated net breakdown of phosphatidylinositol 4,5-bisphosphate in parotid acinar cells

1982 • 182 citations

Structural and Functional Characterization of Isolated Pancreatic Exocrine Cells

1972 • 160 citations

Effects of secretagogues on [32P]phosphatidylinositol 4,5-bisphosphate metabolism in the exocrine pancreas

1983 • 128 citations

Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in hepatocytes by vasopressin.

1983 • 123 citations

Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle

1980 • 122 citations

A simple system for the measurement of ion activities with solvent polymeric membrane electrodes

1979 • 120 citations

The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin

1981 • 109 citations

Intracellular free calcium concentrations in isolated pancreatic acini; Effects of secretagogues

1983 • 107 citations

Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate

1984 • 74 citations

Effects of carbachol and pancreozymin (cholecystokinin-octapeptide) on polyphosphoinositide metabolism in the rat pancreas in vitro

1984 • 44 citations